Medicine and Health Sciences Commons^™

Effects And Moderators Of Psychosocial Interventions On Quality Of Life, And Emotional And Social Function In Patients With Cancer: An Individual Patient Data Meta-Analysis Of 22 Rcts, J. Kalter, I. M. Verdonck-De Leeuw, M. G. Sweegers, N. K. Aaronson, P. B. Jacobsen, R. U. Newton, K. S. Courneya, J. F. Aitken, J. Armes, C. Arving, L. J. Boersma, A. M.J. Braamse, Y. Brandberg, S. K. Chambers, J. Dekker, K. Ell, R. J. Ferguson, M. F.M. Gielissen, B. Glimelius, M. M. Goedendorp, K. D. Graves, Sue P. Heiney, R. Horne, M. S. Hunter, B. Johansson, M. L. Kimman, H. Knoop

Faculty Publications

Objective: This individual patient data (IPD) meta-analysis aimed to evaluate the effects of psychosocial interventions (PSI) on quality of life (QoL), emotional function (EF), and social function (SF) in patients with cancer, and to study moderator effects of demographic, clinical, personal, and intervention-related characteristics. Methods: Relevant studies were identified via literature searches in 4 databases. We pooled IPD from 22 (n = 4217) of 61 eligible randomized controlled trials. Linear mixed-effect model analyses were used to study intervention effects on the post-intervention values of QoL, EF, and SF (z-scores), adjusting for baseline values, age, and cancer type. We studied …