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Articles 1 - 13 of 13
Full-Text Articles in Medicine and Health Sciences
Does Sertraline Decrease Depression In Patients Who Suffered A Traumatic Brain Injury (Tbi)?, Christina Costantino
Does Sertraline Decrease Depression In Patients Who Suffered A Traumatic Brain Injury (Tbi)?, Christina Costantino
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Does sertraline decrease depression in patients who suffered a traumatic brain injury (TBI)?”
STUDY DESIGN: Review of three randomized controlled trials (RCTs) published in English between 2009-2016.
DATA SOURCES: One RCT and two double-blind, placebo-controlled, RCTs found via PubMed evaluated the benefit of the antidepressant drug, sertraline (Zoloft), in decreasing depression in patients who suffered a TBI.
OUTCOMES MEASURED: Main outcomes were measured using the DSM-IV, Hamilton Rating Score for Depression (HAM-D)6 , Beck Anxiety Inventory (BAI)6 , and the Life-3 quality of life (QOL)6 , …
Does Transcutaneous Vagal Nerve Stimulation (T-Vns) Reduce Seizure Frequency In Adult Patients With Pharmacoresistent Epilepsy?, Scott Poirier
Does Transcutaneous Vagal Nerve Stimulation (T-Vns) Reduce Seizure Frequency In Adult Patients With Pharmacoresistent Epilepsy?, Scott Poirier
PCOM Physician Assistant Studies Student Scholarship
Objective The objective of this selective EBM review is to determine whether or not transcutaneous vagal nerve stimulation is an effective measure in reducing seizure frequency in adult patients with pharmacoresistant epilepsy.
Study Design This systematic review comprises a randomized controlled trial and an observational pilot study, both published in 2014, as well as a double-blind randomized control trial published in 2016.
Data Sources All articles were published and displayed in English. The articles were obtained via the PubMed database.
Outcomes Measured Reductions in average seizure frequency were analyzed based on data from patient seizure diaries. Secondary outcomes, including quality …
Is Methylphenidate Effective In Reducing Apathy Among Alzheimer’S Disease Patients?, Jeremy Rinaldi
Is Methylphenidate Effective In Reducing Apathy Among Alzheimer’S Disease Patients?, Jeremy Rinaldi
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE The objective of this selective EBM review is to determine whether or not “Is methylphenidate effective in reducing apathy among Alzheimer’s disease patients?”
STUDY DESIGN Systematic review of two randomized controlled trials published in 2008 and 2013 and one open label study published in 2010.
DATA SOURCES Two randomized controlled trials and one open label study were obtained using PubMed and Medline.
OUTCOMES MEASURED The focus of this review is to determine the efficacy of methylphenidate in decreasing symptoms of apathy in Alzheimer’s disease patients. The efficacy of methylphenidate was assessed in all three studies by using the Apathy …
Does Yoga Improve Symptoms In Patients With Parkinson’S Disease?, Victoria L. Starner
Does Yoga Improve Symptoms In Patients With Parkinson’S Disease?, Victoria L. Starner
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not yoga improved symptoms in patients with Parkinson’s disease.
STUDY DESIGN: A systematic review of three peer-reviewed primary studies published between 2014 and 2018.
DATA SOURCES: Two randomized control trials and one before and after case study evaluating if yoga can improve symptoms for patients who are diagnosed with Parkinson’s disease.
OUTCOMES MEASURES: The outcomes that were measured were balance and movement speed. Balance was measured using single leg balance test, single leg stance, and Berg Balance Scale. Movement speed, bradykinesia, was measured using the Unified Parkinson’s …
Is The Use Of Methylcobalamin Alone Or In Combination With Lidocaine Clinically More Effective Than Lidocaine Alone In Relieving Herpes Zoster Related Neuropathic Pain With Subcutaneous Injections?, Rachel N. Todd
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not Methylcobalamin alone or in combination with Lidocaine is clinically more effective than Lidocaine alone in relieving Herpes Zoster related neuropathic pain with subcutaneous injections.
STUDY DESIGN: This is a systematic review of three peer-reviewed primary studies. All were randomized, controlled trials published between the years of 2014 and 2016.
DATA SOURCES: Data sources obtained for this review were published in peer reviewed journals and selected from PubMed Database.
OUTCOME MEASURED: The outcomes measured reflected the effectiveness of incorporating subcutaneous Methylcobalamin in the treatment regimen for neuropathic …
Is Cannabis Effective In Reducing Muscle Spasticity And Body Pain Amongst Patients With Multiple Sclerosis?, William E. Johnson
Is Cannabis Effective In Reducing Muscle Spasticity And Body Pain Amongst Patients With Multiple Sclerosis?, William E. Johnson
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not cannabis is effective in reducing muscle spasticity and body pain amongst patients with Multiple Sclerosis (MS).
STUDY DESIGN: A systematic review of three peer-reviewed studies published between the years of 2003 and 2012.
DATA SOURCES: Three randomized control trials (RCTs) evaluating if cannabis can reduce muscle spasticity and body pain for patients diagnosed with Multiple Sclerosis. All three sources were selected from PubMed and examined for outcomes that were patient oriented.
OUTCOMES MEASURED: The two primary outcomes measured include: muscle spasticity measured by the Ashworth scale, …
Is Treadmill Training Effective In Improving Postural Instability, Balance, And Gait In Patients With Parkinson Disease?, Katelyn A. Matekovic
Is Treadmill Training Effective In Improving Postural Instability, Balance, And Gait In Patients With Parkinson Disease?, Katelyn A. Matekovic
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not treadmill training is effective in improving postural instability, balance, and gait in patients with Parkinson disease.
STUDY DESIGN: A systematic review of three peer-reviewed primary studies published between the years of 2013 and 2017.
DATA SOURCES: Three randomized controlled trials comparing the efficacy of treadmill training for improving postural instability, balance, and gait for patients with Parkinson Disease. Sources were selected from PubMed based off of the relevance to the clinical question and if they include patient oriented outcome measures.
OUTCOMES MEASURED: The outcomes measured in …
Does Music Therapy Intervention Have An Effect On The Emotional Behavior Of Alzheimer Patients?, Alexandra P. Lahurd
Does Music Therapy Intervention Have An Effect On The Emotional Behavior Of Alzheimer Patients?, Alexandra P. Lahurd
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not music therapy intervention have an effect on emotional behavior of Alzheimer patients. Behavior variables measuring are agitation and anxiety.
STUDY DESIGN: Systematic review of two randomized, controlled trials published in 2009 and 2014, respectively, and one randomized control case study published in 2006.
DATA SOURCE: Three published studies comparing music therapy intervention on behavioral modifications with Alzheimer patients were found using PubMed and Medline
OUTCOMES MEASURES: All three studies measure behavior in Alzheimer patients based on a variety of well validated …
Is The Use Of Kinesio Tape (Kt) Effective In Improving Gross Motor Functionality Throughout The Sit-To-Stand Transfer Activity In Children With Cerebral Palsy (Cp)?, Rachel L. Dodies
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not Kinesio tape (KT) is effective in improving gross motor functionality throughout the sit-to-stand transfer activity in children with cerebral palsy (CP).
Study Design: Review of three English language primary studies published between 2011 and 2015.
Data Sources: One not-blinded randomized controlled trial (RCT), one single-blind RCT, and one cross-sectional study were found using the PubMed database.
Outcomes Measured: The outcomes that were measured were improvement in gross motor function, sitting posture, functional independence, balance, ambulation, and agility from sitting to standing. This …
Is The Use Of The Chinese Herbal Medicine, Ningdong Granule, A Safe And Effective Alternative To Haloperidol For The Treatment Of Tic Symptoms In Pediatric Patients With Tourette Syndrome (Ts)?, Vincent Russell
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE The objective of this selective EBM review is to determine whether the Chinese herbal supplement, Ningdong granule, is a safe and effective alternative to haloperidol for the treatment of tic symptoms in pediatric patients with Tourette Syndrome.
STUDY DESIGN Systematic review of three randomized controlled trials published in 2009, 2010, and 2012.
DATA SOURCES Three randomized controlled trials were obtained using PubMed.
OUTCOMES MEASURED Efficacy of Ningdong granule (NDG) as compared to control groups based on decrease in tic severity and frequency as reported by Yale Global Tic Severity Scale as well as safety, as evidenced by prevalence of …
Is Droxidopa Safe And Effective In Reducing Symptoms Of Neurogenic Orthostatic Hypotension?, Nicholas W. Longo
Is Droxidopa Safe And Effective In Reducing Symptoms Of Neurogenic Orthostatic Hypotension?, Nicholas W. Longo
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not droxidopa is safe and effective in reducing the symptoms of neurogenic orthostatic hypotension.
Study Design: Systemic review of three English-language primary studies, conducted in 2014 or later.
Data Sources: Three double-blind, randomized trials comparing the safety and efficacy of droxidopa to placebo in patients with diagnosed neurogenic orthostatic hypotension, found via PubMed in peer-reviewed journals.
Outcomes Measured: Improvement of symptoms was measured utilizing patient responses to the Orthostatic Hypotension Questionnaire (OHQ), which consists of a six item Orthostatic Hypotension Symptom Assessment (OSHA) …
Does Etravirine Decrease Central Nervous System (Cns)/Neuropsychiatric (Nps) Adverse Events Compared To Efavirenz, In Hiv Positive Patients?, Angelo D. T. Smith
Does Etravirine Decrease Central Nervous System (Cns)/Neuropsychiatric (Nps) Adverse Events Compared To Efavirenz, In Hiv Positive Patients?, Angelo D. T. Smith
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not Etravirine (ETR) decreases adverse reactions on the central nervous system (CNS) compared to Efavirenz (EFV) in Human Immunodeficiency Virus (HIV) positive patients.
STUDY DESIGN: Review of three, English language, primary randomized controlled trial studies published in 2011.
DATA SOURCES: Three randomized controlled trials studying the possible decrease of ADR’s in HIV positive patients who are taking Efavirenz compared to study medication Etravirine.
OUTCOME(S) MEASURED: Outcomes measured were by surveys from patients that assess the development or cessation of CNS ADR’s. The self …
Is Pramipexole Safe And Effective In Reducing Depressive Symptoms In Patients With Mild To Moderate Parkinson’S Disease And Depression?, Corinne J. Kern
Is Pramipexole Safe And Effective In Reducing Depressive Symptoms In Patients With Mild To Moderate Parkinson’S Disease And Depression?, Corinne J. Kern
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not pramipexole (Mirapex) is a safe and effective drug to treat depression in patients with mild to moderate Parkinson’s Disease (PD).
STUDY DESIGN: Review of three English language primary randomized controlled trials and one randomized prospective, observational study published between 2003-2010.
DATA SOURCES: Three randomized controlled trials and one randomized prospective, observational study comparing the efficacy of pramipexole to placebo, sertraline (an SSRI) and other dopamine agonists (pergolide) in the treatment of PD related depression symptoms were found using PubMed.
OUTCOME(S) MEASURED: Each of the …