Medicine and Health Sciences Commons^™

Cytokine Variations And Mood Disorders: Influence Of Social Stressors And Social Support, Marie-Claude Audet, Robyn J. Mcquaid, Zul Merali, Hymie Anisman

Brain and Mind Institute

Stressful events have been implicated in the evolution of mood disorders. In addition to brain neurotransmitters and growth factors, the view has been offered that these disorders might be provoked by the activation of the inflammatory immune system as well as by de novo changes of inflammatory cytokines within the brain. The present review describes the impact of social stressors in animals and in humans on behavioral changes reminiscent of depressive states as well as on cytokine functioning. Social stressors increase pro-inflammatory cytokines in circulation as well as in brain regions that have been associated with depression, varying with the …

Stress And Depression During Pregnancy Among Hispanic Women: Risk For Adverse Birth Outcomes And The Role Of Physical Activity, Kathleen Szegda

Doctoral Dissertations

Preterm birth and low birth weight are among the leading causes of infant mortality and morbidity in the United States. Puerto Rican women are at increased risk for these adverse birth outcomes and elevated levels of depression and psychosocial stress during pregnancy when compared to non-Hispanic Whites. Therefore, it is important to understand whether these psychological factors increase risk for these adverse birth outcomes and mechanisms to prevent/reduce depression in this high-risk population. The first study of this dissertation examined associations between perceived stress during pregnancy and preterm birth, low birth weight, and birth of a small-for-gestational age infant (SGA) …

Modeling Hedonic Processing And Anhedonia In Depression, Kevin Mercado

Honors College Theses

Depression is characterized by low positive emotion and a lack of pleasurable experiences, or anhedonia. Past studies have emphasized controlling negative affect, but there is an emerging trend in the depression literature to focus on positive emotion. The current study employed several psychophysiological tools, postauricular reflex, startle blink reflex, and event-related potential (ERP) components such as P3 and the late positive potential (LPP), to assess the dissociable components in positive emotion (consummatory and anticipatory processes). In addition, several different hypotheses of emotional dysfunction were evaluated to accurately model deficits in positive emotionality. A majority of the psychophysiological tools used supported …

Using The Minority Stress Model To Understand Depression In Lesbian, Gay, Bisexual, And Transgender Individuals In Nebraska, Molly Mccarthy, Christopher M. Fisher, Jay A. Irwin, Jason D. Coleman, Aja D. Kneip Pelster

Sociology and Anthropology Faculty Publications

Previous studies demonstrated the utility of the minority stress model in understanding health disparities for lesbian, gay, bisexual, and transgender (LGBT) populations. Since most research has considered large metropolitan areas, predominantly in coastal regions of the United States, this research focuses on a midwestern state, Nebraska. This study sought to assess the relationships between depressive symptoms experienced by participants (N = 770) and minority stress variables, including experiences with violence, perceptions of discrimination, and respondents’ degree of self-acceptance of their LGBT identity. Regression analysis revealed that after controlling for demographic variables, self-acceptance, and perceived discrimination were correlated with depressive symptoms. …

Treatment Outcomes For Mood Disorders With Concurrent Partner Relational Distress: A Comparison By Treatment Modality And Profession, Holly Pack

Theses and Dissertations

Mood disorders are often linked with concurrent partner relational distress. The present study compared the cost effectiveness of treating mood disorder alone versus when the condition is comorbid with partner relational distress. Cigna, a leading health insurance management company in the US, provided outpatient data. Participants included patients with solely a mood disorder diagnosis (n = 72,712) and those with both a mood disorder and a comorbid partner relational distress diagnosis (n = 113, including 69 females and 44 males). These participants were treated in outpatient settings throughout the US. These numbers are surprisingly low considering the extensive literature showing …

The Impact Of Parentification On Depression Moderated By Self-Care: A Multiple Group Analysis By Gender For South Korea And The U.S., Sunnie Giles

Theses and Dissertations

Parentification, the process of role reversal between parent and child, has long-term deleterious consequences. Using 500 men and 501 women, ranging from 18 years to 55 years old, residing in Korea and the U.S., this study examined the relationship of parentification experienced during childhood and depression in adulthood. The moderating impact of gender and self-care was examined in both the Korean and U.S. samples. Multiple-group analysis showed that the relationship between parentification and depression was statistically significant in all groups (U.S., Korean, male, and female), and self-care was negatively linked to depression. However, self-care did not moderate the relationship between …

Testing A Model Of Maladaptive Perfectionism And Depression Symptoms: The Roles Of Emotional Disclosure, Emotion Regulation Strategies, Adult Attachment, And Shame, Angela M. Garrison

Dissertations

Previous research has supported a link between maladaptive perfectionism and higher levels of depression symptoms. However, researchers have not yet investigated the ways in which emotion regulation processes may mediate this relationship. Therefore, the primary purpose of this study was to evaluate emotional disclosure, emotional avoidance, and rumination as mediators of the relation between maladaptive perfectionism and depression symptoms. Additionally, this study also investigated the role that insecure attachment orientations play in the relationship between maladaptive perfectionism and use of particular emotion regulation strategies. Further, the role of shame in the emotion regulation processes of individuals with higher levels of …

Women's Experiences Living With Depression, Susan Marie Jarchow

Theses and Dissertations

In the United States, depression affects many Americans at different levels. Depression among women is a major public health problem. According to the National Alliance on Mental Illness), about 1 in 5 women develop depression at some point in their lives, and are nearly twice as likely as men to have depression. Much of the research about depression in women are quantitative studies aimed mostly at collecting epidemiological or survey data that focus on rates of mental illness, while not taking into account the qualitative subjective and contextual illness perspectives of women living with depression.

The purpose of this study …

Physical Activity Helping To Reduce Depression, Ellen Margaret Bier

Chancellor’s Honors Program Projects

No abstract provided.

A Pilot Study Of Qigong For Reducing Cocaine Craving Early In Recovery, David A. Smelson, Kevin W. Chen, Douglas M. Ziedonis, Ken Andes, Amanda Lennox, Lanora Callahan, Stephanie Rodrigues, David Eisenberg

Douglas M. Ziedonis

OBJECTIVES: This pilot study examined the feasibility, preliminary efficacy, and determined the effect sizes of external qigong therapy (EQT) in reducing cue-elicited cocaine craving and associated symptoms among recently abstinent cocaine-dependent (CD) individuals. METHODS: This study randomized 101 CD subjects to either a real EQT (n=51) or sham EQT control (n=50) group. Subjects underwent a baseline assessment and a weekly cue-exposure session for 2 weeks. Total EQT or sham treatments ranged from 4 to 6 sessions in 2 weeks. RESULTS: EQT-treated subjects displayed a greater reduction in cue-elicited craving (p=0.06) and symptoms of depression (p<0.05) with medium effect sizes. …

Depression Is More Prevalent Throughout Pregnancy And The First Six Months Postpartum In Women Low In Religious Commitment And Social Support, Andrea D. Clements, Tifani A. Fletcher, Beth A. Bailey

ETSU Faculty Works

Abstract available through the Annals of Behavioral Medicine.

Religiosity, Spirituality, And Depressive Symptoms In Older Adults In An Active Living Community, Monica D'Adrianne Solomon

USF Tampa Graduate Theses and Dissertations

The population of older adults in the United States is steadily rising. The Centers for Disease Control and Prevention (CDC) recently released a call to reduce mental distress in older adults. Research shows that mental distress is associated with depressive symptoms, which are significantly related to many chronic medical conditions, functional impairment, suicide, and all-cause mortality. Depression is a major public health concern. There is an interest in gerontology research on the buffering role of engagement against depressive symptoms such as volunteering, social activities, and religion. Certain religious beliefs and behaviors contribute to maintaining or improving mental health and research …

Evolutionary Cognitive Therapy Versus Standard Cognitive Therapy For Depression: A Protocol For A Blinded, Randomized, Superiority Clinical Trial, Cezar Giosan, Oana Cobeanu, Cristina Mogoase, Vlad Muresan, Loretta S. Malta, Katarzyna Wyka, Aurora Szentagotai

Publications and Research

Background: Depression is estimated to become the leading cause of disease burden globally by 2030. Despite existing efficacious treatments (both medical and psychotherapeutic), a large proportion of patients do not respond to therapy. Recent insights from evolutionary psychology suggest that, in addition to targeting the proximal causes of depression (for example, targeting dysfunctional beliefs by cognitive behavioral therapy), the distal or evolutionary causes (for example, inclusive fitness) should also be addressed. A randomized superiority trial is conducted to develop and test an evolutionary-driven cognitive therapy protocol for depression, and to compare its efficacy against standard cognitive therapy for depression.

Methods/design: …

Firesetting Behavior And Psychiatric Disorders, Stephanie Stockburger, Hatim A. Omar

Pediatrics Faculty Publications

Firesetting behavior results in serious damage to lives and property every year. Firesetting has been linked to a number of comorbid psychiatric disorders including depression, substance abuse, conduct disorder, antisocial personality disorder, obsessive compulsive disorder, psychotic disorder, schizoid personality disorder, and schizophrenia. Psychiatric disorders differ by gender. In addition, juvenile firesetters have history of a separate set of psychiatric comorbidities. The strong correlation between psychiatric comorbidities and firesetting behavior illustrates the need for fire service and mental health collaboration.

A Pilot Study On The Effects Of Exercise On Depression Symptoms Using Levels Of Neurotransmitters And Eeg As Markers, Timothy H. Barclay, Scott Richards, James Schoffstall, Chad Magnuson, Christine Mcphee, Josh Price, Stephen Aita, Audrey Anderson, Dan Johnson, Jerry Price

Faculty Publications and Presentations

Context: The prescribing of exercise by physicians has become a popular practice, yet the effectiveness of exercise on symptoms of depression is difficult to determine due to a lack of randomized controlled trials with clinical populations. Reports also indicate that only a small percentage of physicians advise their patients regarding exercise and confusion still exists as to how much and what types are best. Aims: To understand the mechanisms that make exercise a viable treatment in depression. Settings and Design: This study employed a six‑week, two group, single‑level trial, pre‑ and posttest design using self‑report of symptoms, blood …

Severe Depressive Symptoms Predict Individual And Partner Infertility-Related Distress At One-Year Follow-Up, Brennan Peterson, Camilla Sejbaek, Matthew Pirritano, Lone Schmidt

Marriage and Family Therapy Faculty Presentations

Poster presentation on whether severe depressive symptoms at baseline are a predictor of individual and partner infertility-related distress after one-year of unsuccessful fertility treatments.

Coping Responses And Mental Health Symptoms In Incarcerated Juvenile Males, Jennifer Renae Newhard

Antioch University Full-Text Dissertations & Theses

Coping responses develop throughout the lifespan of an individual. Unfortunately for some, difficult life circumstances may lead to the use of maladaptive forms of coping. This study investigated coping responses amongst male incarcerated juvenile offenders and examined which specific mental health symptoms may occur with specific coping responses. The goal of this study was to determine whether male incarcerated juvenile offenders utilize avoidant coping responses over approach coping responses. Also, this study investigated whether specific mental health symptoms, such as depression, anxiety, anger, and disruptive behaviors, were more prevalent amongst those who utilize avoidant coping responses. De-identified, archival data for …

Effects Of Parental Alcoholism And Trauma Exposure On Depressive Symptoms: A Path Model With Resilience, Social Support, And Family Satisfaction, Erin Doty Kurtz

Psychology Theses & Dissertations

The goal of this study was to explore the different effects of parental alcoholism and history of trauma exposure on depressive symptoms in an emerging adult, college population. In particular, mediating effects of resilience, social support, and family satisfaction were evaluated for both parental alcoholism and previous interpersonal trauma exposure using structural equation modeling (SEM). Participants were 708 students (217 male, 491 female) attending a large mid-Atlantic state university. It was . anticipated that social support and family satisfaction would be key mediators between parental alcoholism and depressive symptoms, while resilience and social support would be significant mediators between interpersonal …