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Full-Text Articles in Medicine and Health Sciences
The Effects Of Nicotine Conditioned Place Preference In D2 Primed Adolescent Rats: Age-Related And Gender Effects., Yoko Emily Ogawa
The Effects Of Nicotine Conditioned Place Preference In D2 Primed Adolescent Rats: Age-Related And Gender Effects., Yoko Emily Ogawa
Electronic Theses and Dissertations
This study investigated nicotine conditioned place preference (CPP) in two different ages of adolescence using a rodent model of schizophrenia. Both 2- and 3-chambered CPP apparatuses were used to test whether the CPP was due to an aversion to the white chamber. Animals were neontally treated with the dopamine D2/D3 agonist, quinpirole, or saline and raised to either early postweanling age (P 22) or adolescence (P 29). Rats were conditioned to prefer the white chamber using nicotine. Results showed that nicotine induced CPP and appeared to alleviate an increased stress response in D2 primed animals, which …
Posttraumatic And Parent Stress In Parents Of Infant Heart Transplant Recipients, Jessie Rose Stevens
Posttraumatic And Parent Stress In Parents Of Infant Heart Transplant Recipients, Jessie Rose Stevens
Loma Linda University Electronic Theses, Dissertations & Projects
Heart transplantation during infancy is a life-threatening event, and when successful, the treatment is a life-long process and the potential for life-threatening consequences never ceases. As a result, parents can be impacted in many ways by this traumatic and demanding experience that begins with the initial diagnosis of their infant and continues into the long-term life course of these children. This life-long process has the potential to cause symptoms of posttraumatic stress disorder as well as elevated levels of stress in parents. This study examined parental self-reported post-traumatic stress symptoms and parental stress in parents of children who received a …
Effects Of Distress On Health Care Utilization In Cancer Survivors (Nhis 2004), Natalie Christine Kaiser
Effects Of Distress On Health Care Utilization In Cancer Survivors (Nhis 2004), Natalie Christine Kaiser
Loma Linda University Electronic Theses, Dissertations & Projects
Distress rates have been found to be around 43%, as indicated by a study of five comprehensive cancer centers and as measured by the Distress Thermometer (Jacobsen, et ah, 2005). Furthermore, few studies have examined the current health care utilization among cancer patients as predicted by distress. Thus, population-based data from the NHIS (2004) was analyzed using SUDAAN software 1) to ascertain the current levels of distress as measured by the Kessler 6 scale experienced by cancer survivors based upon demographic characteristics, family structure, physical comorbitities, and cancer-related variables, and 2) to determine whether distress rates reported among cancer survivors …
The Relations Of Pain, Religious Coping, And Depression In Fibromyalgia Patients, Derek O. Bacchus
The Relations Of Pain, Religious Coping, And Depression In Fibromyalgia Patients, Derek O. Bacchus
Loma Linda University Electronic Theses, Dissertations & Projects
This study attempted to examine the relationship between Fibromyalgia Syndrome (FMS) pain, religious coping, and depression. The Fibromyalgia Impact Questionnaire (FIQ), Short-Form McGill Pain Questionnaire (SF-MPQ), RCOPE, and the Center for Epidemiologic Studies Depression Scale (CES-D) were used to assess these constructs in 50 participants. The sample was primarily middle aged and female, which is typical of the FMS population. This study used multiple regression to make assumptions about the causal progression of the variables. Study findings show that religious coping does not appear to significantly mediate the strong relationship between FMS pain and depression. This research served to uncover …
An Analysis Of Nicotine Exacerbation Of Reductions In Ppi In A Rodent Model Of Schizophrenia., Amanda Marie Maple
An Analysis Of Nicotine Exacerbation Of Reductions In Ppi In A Rodent Model Of Schizophrenia., Amanda Marie Maple
Electronic Theses and Dissertations
Prepulse inhibition (PPI) is an operational measure of sensorimotor gating and is known to be reduced when the dopamine D2 receptor is activated. We used a rodent model of psychosis in which increases in dopamine D2 receptor sensitivity are produced through neonatal quinpirole (a dopamine D2 / D3 agonist) treatment to rats. Rats were administered quinpirole (1mg/kg) or saline from postnatal day (P) 1-21. Rats were raised to adulthood and tested on PPI. Results showed that neonatal quinpirole treatment produced a significant reduction in PPI, and nicotine exacerbated this reduction. This reduction was partially blocked by …
Nicotine Sensitization In A Rodent Model Of Schizophrenia: A Comparison Of Adolescents, Adults, And Neurotrophic Factors., Marla Kay Perna
Nicotine Sensitization In A Rodent Model Of Schizophrenia: A Comparison Of Adolescents, Adults, And Neurotrophic Factors., Marla Kay Perna
Electronic Theses and Dissertations
The behavioral effects of nicotine on locomotor activity in a rodent model of psychosis were analyzed. This model is based on neonatal quinpriole treatment (a dopamine D2/D3 agonist) which causes increased D2 receptor sensitivity, a phenomenon known as D2 priming that is common in schizophrenia. D2-primed adolescent rats did not demonstrate nicotine-induced hypoactivity early in training, and males demonstrated more rapid sensitization to nicotine as compared to controls administered nicotine. D2-primed females administered nicotine demonstrated increased stereotypic behavior. D2-primed adult rats given nicotine demonstrated significantly more robust sensitization to nicotine than controls given nicotine. Brain-derived neurotrophic factor (BDNF) was analyzed …
Binge Eating, Emotion Regulation, And Cognitive Resources, Jennifer A. Tucker
Binge Eating, Emotion Regulation, And Cognitive Resources, Jennifer A. Tucker
Loma Linda University Electronic Theses, Dissertations & Projects
Research has shown that individuals with binge eating disorder (BED) have difficulty coping with negative emotions, although no research to date has directly investigated emotion regulation and binge eating. In the current study individuals with varying amounts of BED characteristics were measured for accuracy on a computerized task involving attention and working memory. Subsequent to the task, participants were given three self-report measures: the Eating Disorder Examination Questionnaire (EDEQ-I; Fairbum & Celio, 2004), the Positive and Negative Affect Schedule (PANAS; Watson, Clark & Tellgen, 1988), and the Emotion Regulation Questionnaire (ERQ; Gross & John, 2003). It was hypothesized that in …