Medicine and Health Sciences Commons^™

Catatonia In An Adolescent With Velo-Cardio-Facial Syndrome, Gianni Faedda, Lee Wachtel, Anne Marie Higgins, Robert Shprintzen

Robert J. Shprintzen

Velo-cardio-facial syndrome (VCFS) is the most common microdeletion syndrome in humans and is probably the most frequent genetic cause of psychosis currently known. Many psychiatric disorders have been reported to occur in people with VCFS including, but not limited to schizophrenia, unipolar and bipolar mood disorders (with or without psychotic features), schizoaffective disorder, psychosis NOS, social phobia, generalized and separation anxiety, obsessive-compulsive disorder, autism spectrum disorder, cognitive impairment, and ADHD. This report describes the psychiatric onset and development of catatonia in an adolescent female with VCFS that was undiagnosed until 15 years of age. Catatonia may be a relatively common …

Differences In The Prevalence, Severity And Symptom Profiles Of Depression In Boys And Adolescents With An Autism Spectrum Disorder Versus Normally Developing Controls, Vicki Bitsika, Christopher Sharpley

Vicki Bitsika

The prevalence, severity and symptom profiles for major depressive disorder (MDD) were compared in samples of boys and adolescents with and without an autism spectrum disorder (ASD). Self-reports were obtained on the Depression subscale of the Child and Adolescent Symptoms Inventory (CASI-D) with 70 ASD and 50 non-ASD male participants between the ages of 8 and 18 from Queensland, Australia who were matched for age and IQ. Results indicated that the ASD participants had significantly higher total CASI-D scores, a greater proportion of participants who qualified for a diagnosis of MDD, and over 50% higher scores for 8 of the …

Eight-Month Test-Retest Agreement In Morning Salivary Cortisol, Self- And Parent-Rated Anxiety In Boys With An Autism Spectrum Disorder, Christopher Sharpley, Vicki Bitsika, Linda Agnew, Nicholas Andronicos

Vicki Bitsika

The agreement over time in morning salivary cortisol concentrations and also self- and parent-rated anxiety was investigated in a sample of 16 boys with an ASD. Cortisol and anxiety data were collected eight months apart. Results indicated that there were significant correlations between each pair of measures from the two occasions, suggesting that cortisol concentrations and anxiety did not vary much at all over that time, challenging the assumption that cortisol needs to be measured over multiple days to obtain reliable data from children with an ASD. Implications for research into the ways these children respond to chronic stressors are …

Frontal Alpha Asymmetry As A Pathway To Behavioural Withdrawal In Depression: Research Findings And Issues, Emmanuel Jesulola, Christopher Sharpley, Vicki Bitsika, Linda Agnew, Peter Wilson

Vicki Bitsika

Depression has been described as a process of behavioural withdrawal from overwhelming aversive stressors, and which manifests itself in the diagnostic symptomatology for Major Depressive Disorder (MDD). The underlying neurobiological pathways to that behavioural withdrawal are suggested to include greater activation in the right vs the left frontal lobes, described as frontal EEG asymmetry. However, despite a previous meta-analysis that provided overall support for this EEG asymmetry hypothesis, inconsistencies and several methodological confounds exist. The current review examines the literature on this issue, identifies inconsistencies in findings and discusses several key research issues that require addressing for this field to …

The Saint Of Worcester: Why Pilgrims Visit Audrey Santo, Mathew Schmalz

Mathew Schmalz

No abstract provided.

Use Of Medications Of Questionable Benefit In Advanced Dementia, Jennifer Tjia, Becky Briesacher, Daniel Peterson, Qin Liu, Susan Andrade, Susan Mitchell

Jennifer Tjia

IMPORTANCE: Advanced dementia is characterized by severe cognitive impairment and complete functional dependence. Patients' goals of care should guide the prescribing of medication during such terminal illness. Medications that do not promote the primary goal of care should be minimized. OBJECTIVES: To estimate the prevalence of medications with questionable benefit used by nursing home residents with advanced dementia, identify resident- and facility-level characteristics associated with such use, and estimate associated medication expenditures. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study of medication use by nursing home residents with advanced dementia using a nationwide long-term care pharmacy database linked to the Minimum Data …

Predictors Of Depression In Prostate Cancer Patients: A Comparison Of Psychological Resilience Versus Pre-Existing Anxiety And Depression, Christopher Sharpley, Vicki Bitsika, Addie Wootten, David Christie

Vicki Bitsika

Background: Previous anxiety and depression can influence current anxiety and depression, and psychological resilience may be a buffer against current anxiety and depression. However, despite the relevance of these two sets of predictors of anxiety and depression, and their potential in treatment planning, no reports have been published on their role in post-diagnosis anxiety and depression among prostate cancer (PCa) patients. Therefore, this study aimed to determine the roles of these predictors in a sample of men with prostate cancer. Method: Retrospective self-reports of anxiety and depression for how they were before receiving their diagnosis of PCa and at the …

Rationales That Providers And Family Members Cited For The Use Of Antipsychotic Medications In Nursing Home Residents With Dementia, Alice Bonner, Terry Field, Celeste Lemay, Kathleen Mazor, Daniel Andersen, Christina Compher, Jennifer Tjia, Jerry Gurwitz

Jennifer Tjia

OBJECTIVES: To describe the rationales that providers and family members cite for the use of antipsychotic medications in people with dementia living in nursing homes (NHs). DESIGN: Qualitative, descriptive study. SETTING: Twenty-six medium-sized and large facilities in five Centers for Medicare and Medicaid Services regions. PARTICIPANTS: Individuals diagnosed with dementia who received an antipsychotic medication. MEASUREMENTS: Data were collected from medical record abstraction and interviews with prescribers, administrators, direct care providers, and family members. Textual data from medical record abstraction and responses to open-ended interview questions were analyzed using directed content analysis techniques. A coding scheme was developed, and coded …

Statin Discontinuation In Nursing Home Residents With Advanced Dementia, Jennifer Tjia, Sarah Cutrona, Daniel Peterson, George Reed, Susan Andrade, Susan Mitchell

Jennifer Tjia

OBJECTIVES: To describe patterns of, and factors associated with, statin use and discontinuation in nursing home (NH) residents progressing to advanced dementia and followed for at least 90 days.

DESIGN: Retrospective inception cohort using a dataset linking 2007 to 2008 Minimum Data Set (MDS) to Medicare denominator and Part D files.

SETTING: All NHs in five states (Minnesota, Massachusetts, Pennsylvania, California, Florida).

PARTICIPANTS: NH residents with dementia.

MEASUREMENTS: Residents who developed advanced dementia were observed from baseline (date of progression to very severe cognitive impairment with eating problems) and followed for at least 90 days to statin discontinuation or death. …

Personality Disorder Risk Factors For Suicide Attempts Over 10 Years Of Follow-Up, Emily B. Ansell, Aidan G. C. Wright, John C. Markowitz, Charles A. Sanislow, Christopher J. Hopwood, Mary C. Zanarini, Shirley Yen, Anthony Pinto, Thomas H. Mcglashan, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

Identifying personality disorder (PD) risk factors for suicide attempts is an important consideration for research and clinical care alike. However, most prior research has focused on single PDs or categorical PD diagnoses without considering unique influences of different PDs or of severity (sum) of PD criteria on the risk for suicide-related outcomes. This has usually been done with cross-sectional or retrospective assessment methods. Rarely are dimensional models of PDs examined in longitudinal, naturalistic prospective designs. In addition, it is important to consider divergent risk factors in predicting the risk of ever making a suicide attempt versus the risk of making …

The Phenomenology Of Intersubjectivity In Jaspers And Husserl: On The Capacities And Limits Of Empathy And Communication In Psychiatric Praxis, Sebastian Luft, J. Schlimme

Sebastian Luft

In this article, we present two accounts of intersubjectivity in Jaspers and Husserl, respectively. We argue that both can be brought together for a more satisfying account of empathy and communication in the context of psychiatric praxis. But while we restrict ourselves for the most part to this praxis, we also indicate the larger agenda that drives Jaspers and Husserl, despite all disagreement. Here we spell out, in particular, how a phenomenologically inspired account of empathy and intersubjectivity can have larger ramifications for a theory of social life and interaction. Finally, we argue for a ‘relaxed' view concerning the relation …

Introduction: A Changing Indonesia, Maribeth Erb, Kathleen M. Adams

Kathleen M. Adams

No abstract provided.

Interactions Of Borderline Personality Disorder And Anxiety Disorders Over Ten Years, Alex S. Keuroghlian,, John G. Gunderson, Maria E. Pagano, John C. Markowitz, Emily B. Ansell, M. Tracie Shea, Leslie C. Morey, Charles A. Sanislow, Carlos M. Grilo, Robert L. Stout, Mary C. Zanarini, Thomas H. Mcglashan, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

Ptsd/Sud In Individuals With Physical Disabilities: Identifying Problems And Promising Interventions, Melissa L. Anderson, Douglas M. Ziedonis, Lisa M. Najavits

Melissa L. Anderson

Co-occurring posttraumatic stress disorder (PTSD) and substance use disorder (SUD) is common, affects multiple domains of functioning, and presents complex challenges to recovery. Initial research indicates that individuals with physical disabilities experience higher rates of lifetime trauma and PTSD, and exhibit more severe SUD compared to non-disabled individuals. To expand upon these initial findings, we conducted a series of two studies on PTSD and SUD among individuals with physical disabilities.

Internal Consistency And Factor Structure Of The Revised Conflict Tactics Scales In A Sample Of Deaf Female College Students, Melissa Anderson, Irene Leigh

Melissa L. Anderson

The Revised Conflict Tactics Scales (CTS2) is currently the most widely used measure for identifying cases of intimate partner violence within the hearing population. The CTS2 has been used successfully with individuals from various countries and cultural backgrounds. However, the CTS2 had not yet been used with Deaf individuals. The goal of the present study was to investigate the internal consistency reliability and the factor structure of the CTS2 within a sample of Deaf female college students. Psychometric analyses indicated that subscales measuring Victimization of Negotiation, Psychological Aggression, Physical Assault, and Injury proved both reliable and valid in the current …