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Meta-Analysis Of Randomized Clinical Trials Comparing Open And Laparoscopic Anti-Reflux Surgery, Matthew Peters, Athar Mukhtar, Rossita Yunus, Shahjahan Khan, Juanita Pappalardo, Breda Memon, Muhammed Memon
Meta-Analysis Of Randomized Clinical Trials Comparing Open And Laparoscopic Anti-Reflux Surgery, Matthew Peters, Athar Mukhtar, Rossita Yunus, Shahjahan Khan, Juanita Pappalardo, Breda Memon, Muhammed Memon
Muhammed Ashraf Memon
OBJECTIVES: The aim of this study was to conduct a meta-analysis of randomized evidence to determine the relative merits of laparoscopic anti-reflux surgery (LARS) and open anti-reflux surgery (OARS) for proven gastro-esophageal reflux disease (GERD).
METHODS: A search of the Medline, Embase, Science Citation Index, Current Contents, and PubMed databases identified all randomized clinical trials that compared LARS and OARS and that were published in the English language between 1990 and 2007. A meta-analysis was carried out in accordance with the QUOROM (Quality of Reporting of Meta-Analyses) statement. The six outcome variables analyzed were operating time, hospital stay, return to …