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Full-Text Articles in Medicine and Health Sciences
Localized Cytokine Responses To Total Knee Arthroplasty And Total Knee Revision Complications, Nicole Prince, Julia A. Penatzer, Matthew J. Dietz, Jonathan W. Boyd
Localized Cytokine Responses To Total Knee Arthroplasty And Total Knee Revision Complications, Nicole Prince, Julia A. Penatzer, Matthew J. Dietz, Jonathan W. Boyd
Faculty & Staff Scholarship
Background
The study of localized immune-related factors has proven beneficial for a variety of conditions, and one area of interest in the field of orthopaedics is the impact of implants and localized infections on immune response. Several cytokines have shown increased systemic concentrations (in serum/plasma) in response to implants and infection, but tissue-level cytokines have not been investigated as thoroughly.
Methods
This exploratory study investigated tissue-level cytokines in a cohort of patients (N = 17) in response to total knee arthroplasty and total knee revision to better understand the immune response to implants and localized infection (e.g., prosthetic joint infection). …
A Medial Congruent Polyethylene Offers Satisfactory Early Outcomes And Patient Satisfaction In Total Knee Arthroplasty, Benjamin M. Frye, Caitlyn Patton, Jason A. Kinney, T. Ryan Murphy, Adam E. Klein, Matthew J. Dietz
A Medial Congruent Polyethylene Offers Satisfactory Early Outcomes And Patient Satisfaction In Total Knee Arthroplasty, Benjamin M. Frye, Caitlyn Patton, Jason A. Kinney, T. Ryan Murphy, Adam E. Klein, Matthew J. Dietz
Faculty & Staff Scholarship
Background
Although a successful operation, almost 20% of patients are dissatisfied with total knee arthroplasty (TKA). The purpose of this retrospective cohort study was to see if a medial congruent (MC) polyethylene would offer satisfactory early outcomes and patient satisfaction after TKA.
Methods
We reviewed prospectively collected data on 327 TKAs using multiple bearings within the same implant system. Ninety-six received an MC bearing, 70 received a cruciate-retaining (CR) bearing, and 161 received a posterior-stabilized (PS) bearing. We evaluated the visual analog scale pain scores and range of motion (ROM) at 2 weeks, 6 weeks, 3 months, and 1 year; …