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Atrial fibrillation

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Safety And Long-Term Efficacy Of Thoracoscopic Epicardial Ablation In Patients With Paroxysmal Atrial Fibrillation: A Retrospective Study, John Johnkoski, Bryan Miles, Anna Sudbury, Mohammed Osman, Muhammad Bilal Munir, Sudarshan Balla, Mina M. Benjamin Jan 2019

Safety And Long-Term Efficacy Of Thoracoscopic Epicardial Ablation In Patients With Paroxysmal Atrial Fibrillation: A Retrospective Study, John Johnkoski, Bryan Miles, Anna Sudbury, Mohammed Osman, Muhammad Bilal Munir, Sudarshan Balla, Mina M. Benjamin

Faculty & Staff Scholarship

Background: The aim of this study is to report the long-term efficacy and safety of thoracoscopic epicardial left atrial ablation (TELA) in patients with paroxysmal atrial fibrillation (AF). Methods: This was a retrospective review of medical records. We included all patients diagnosed with paroxysmal AF who underwent TELA at our institution between 04/2011 and 06/2017. TELA included pulmonary vein isolation, LA dome lesions and LA appendage exclusion. All (n = 55) patients received an implantable loop recorder (ILR), 30 days post-operatively. Antiarrhythmic and anticoagulation therapy were discontinued at 90 and 180 days postoperatively, respectively, if patients were free of AF …


Trial Sequential Analysis Comparing Bleeding And Major Adverse Cardiovascular Events In Patients With Atrial Fibrillation And Acute Coronary Syndrome On Dual Versus Triple Therapy, Muhamad B. Munir, Khansa Osman, Maryam Saleem, Kinjan Patel, Sudarshan Balla Jan 2019

Trial Sequential Analysis Comparing Bleeding And Major Adverse Cardiovascular Events In Patients With Atrial Fibrillation And Acute Coronary Syndrome On Dual Versus Triple Therapy, Muhamad B. Munir, Khansa Osman, Maryam Saleem, Kinjan Patel, Sudarshan Balla

Faculty & Staff Scholarship

Objective To assess efficacy and safety of dual therapy (DT) and triple therapy (TT) in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) with or without percutaneous coronary intervention (PCI) and evaluate the quality of evidence with respect to said outcomes based on contemporary randomized trials (RCTs). The efficacy outcome taken was major adverse cardiovascular events (MACE) while safety outcome was major bleeding events. Introduction Appropriate anti-thrombotic therapy is still controversial in patients with AF and concomitant ACS or PCI. We conducted a conventional meta-analysis pooling data from major RCTs to assess the efficacy and safety of DT …


Racial Disparities In The Utilization And Outcomes Of Structural Heart Disease Interventions In The United States, Mohamad Alkhouli, Fahad Alqahtani, David R. Holmes, Chalak Berzingi Jan 2019

Racial Disparities In The Utilization And Outcomes Of Structural Heart Disease Interventions In The United States, Mohamad Alkhouli, Fahad Alqahtani, David R. Holmes, Chalak Berzingi

Faculty & Staff Scholarship

Background-—Data on race- and ethnicity-based disparities in the utilization and outcomes of structural heart disease interventions in the United States are scarce. Methods and Results-—We used the National Inpatient Sample (2011-2016) to examine racial and ethnic differences in the utilization, in-hospital outcomes, and cost of structural heart disease interventions among patients ≥65 years of age. A total of 106 119 weighted hospitalizations for transcatheter aortic valve replacement, transcatheter mitral valve repair, and left atrial appendage occlusion were included. The utilization rates (defined as the number of procedures performed per 100 000 US people >65 years of age) were higher in …