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Integrated Guidance On The Care Of Familial Hypercholesterolaemia From The International Fh Foundation., Gerald F Watts, Samuel Gidding, Anthony S Wierzbicki, Peter P Toth, Rodrigo Alonso, W Virgil Brown, Eric Bruckert, Joep Defesche, Khoo Kah Lin, Michael Livingston, Pedro Mata, Klaus G Parhofer, Frederick J Raal, Raul D Santos, Eric J G Sijbrands, William G Simpson, David R Sullivan, Andrey V Susekov, Brian Tomlinson, Albert Wiegman, Shizuya Yamashita, John J P Kastelein

Division of Cardiology Faculty Papers

Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth that markedly elevates plasma low-density lipoprotein (LDL) cholesterol and causes premature coronary heart disease. There are at least 20million people with FH worldwide, but the majority remain undetected and current treatment is often suboptimal. To address this major gap in coronary prevention we present, from an international perspective, consensus-based guidance on the care of FH. The guidance was generated from seminars and workshops held at an international symposium. The recommendations focus on the detection, diagnosis, assessment and management of FH in adults and children, and set guidelines for clinical …