Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Comparison Of Estrogen Receptors, Progesterone Receptors And Her-2/Neu Expression Between Primary And Metastatic Breast Carcinoma, Muhammad Azam, Asim Qureshi, Samina Mansoor
Comparison Of Estrogen Receptors, Progesterone Receptors And Her-2/Neu Expression Between Primary And Metastatic Breast Carcinoma, Muhammad Azam, Asim Qureshi, Samina Mansoor
Department of Pathology and Laboratory Medicine
OBJECTIVE: To determine whether receptor status and HER-2/neu status remains same in primary and metastatic breast carcinoma to corresponding lymph nodes of individual patients.
METHODS: Estrogen receptors, progesterone receptors and HER-2/neu immunohistochemical stains were performed on primary and metastatic breast carcinoma to axillary lymph nodes in 100 patients. Data was collected on a Performa and age, tumour size, type, grade and expression of ER, PR and HER-2/neu on primary and metastatic tumours were recorded.
RESULTS: Hormone receptor status was compared between primary and metastatic tumours. Estrogen receptor positivity was observed in 28% primary tumours which were reduced to 25% in …