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Full-Text Articles in Medicine and Health Sciences
Research Department Of Radiation Oncology
Research Department Of Radiation Oncology
Bodine Journal
Listing of Basic Research Studies/Grants and Clinical Research Studies/Grants.
Evolving Role Of Vorinostat Combined With Radiation Therapy In The Treatment Of Brain Tumors, From The Lab To The Clinic, Y. R. Lawrence, P. Wachsberger, Y. Liu, B. Andersen, A. P. Dicker
Evolving Role Of Vorinostat Combined With Radiation Therapy In The Treatment Of Brain Tumors, From The Lab To The Clinic, Y. R. Lawrence, P. Wachsberger, Y. Liu, B. Andersen, A. P. Dicker
Bodine Journal
Purpose/Objective(s): Radiation therapy (RT) is a critical element in the treatment of both brain metastases and glioblastoma (GBM). Temozolomide (TMZ) has an established role in the upfront treatment of GBM. Down-regulated mismatch repair (MMR) is a known mechanism of resistance to TMZ. Vorinostat (SAHA), an HDAC inhibitor, has successfully been combined with a number of cytotoxic agents, including ionizing radiation (IR). We performed a series of preclinical and clinical studies to examine the role of SAHA in the treatment of brain tumors.
American Society for Therapeutic Radiation Oncology (ASTRO) 52nd Annual Meeting October 31 - November 4, San Diego, CA
Performance Study Of Novel Accelerationenhanced Filters In The Prediction Of Normal And Irregular Respiration Motion, K. Huang, I. Buzurovic, M. Werner-Wasik, T. Biswas, A. Dicker, J. Galvin, Y. Yu, T. Podder
Performance Study Of Novel Accelerationenhanced Filters In The Prediction Of Normal And Irregular Respiration Motion, K. Huang, I. Buzurovic, M. Werner-Wasik, T. Biswas, A. Dicker, J. Galvin, Y. Yu, T. Podder
Bodine Journal
Purpose: To study the performance of the novel acceleration-enhanced (AE) filters in the prediction of normal and irregular respiration motion and compare them with those of traditional adaptive normalized least mean squares (nLMS) and adaptive neuron network (ANN) filters. This facilitates the real-time tumor tracking and dynamic delivery of radiation dose to the tumor.
American Association of Physicists in Medicine (AAPM) 52nd Annual Meeting July 18-22, Philadelphia, PA
Is Phonophobia Associated With Cutaneous Allodynia In Migraine?, Avi Ashkenazi, Irene Yang, Aamir Mushtaq, Michael L. Oshinsky
Is Phonophobia Associated With Cutaneous Allodynia In Migraine?, Avi Ashkenazi, Irene Yang, Aamir Mushtaq, Michael L. Oshinsky
Department of Neurology Faculty Papers
ABSTRACT
Objective
To determine whether phonophobia and dynamic mechanical (brush) allodynia are associated in episodic migraine (EM).
Methods
Adult patients with EM were prospectively recruited. A structured questionnaire was used to obtain demographic and migraine related data. Phonophobia was tested quantitatively using a real time sound processor and psychoacoustic software. Sound stimuli were pure tones at frequencies of 1000 Hz, 4000 Hz and 8000 Hz, delivered to both ears at increasing intensities, until an aversive level was reached. Allodynia was assessed by brushing the patient’s skin with a gauze pad at different areas. Patients were tested both between and during …
Pregnancy Outcomes In Female Lung Transplant Recipients, Julie Shaner, Faith Carlin, Lisa A. Coscia, Carolyn H. Mcgrory, Dawn Armenti, Vincent T. Armenti
Pregnancy Outcomes In Female Lung Transplant Recipients, Julie Shaner, Faith Carlin, Lisa A. Coscia, Carolyn H. Mcgrory, Dawn Armenti, Vincent T. Armenti
Department of Surgery Faculty Papers
Conclusions:
Female lung recipients appear to face higher risks related to pregnancy when compared to other solid organ transplant recipients.
Although successful pregnancies have been reported in female lung recipients, analyses of larger numbers of cases may help to identify pre-pregnancy factors predictive of adverse outcomes.
Centers are encouraged to report all pregnancies in transplant recipients to the NTPR.
The Use Of The Use Of Negative Pressure Wound Therapy In Vulvar Wounds, E. K. Ricci, Md, J. Brace, Phd, Crn, Bc, Cwocn, Aprn, N. G. Rosenblum, Md, Phd
The Use Of The Use Of Negative Pressure Wound Therapy In Vulvar Wounds, E. K. Ricci, Md, J. Brace, Phd, Crn, Bc, Cwocn, Aprn, N. G. Rosenblum, Md, Phd
Department of Obstetrics and Gynecology Faculty Papers
Patients with severe HS or Necrotizing Fasciitis often require extensive surgical debridement.
Traditionally, these wounds have been closed using split-thickness skin grafts with or without the use of the VAC device.
Our case study demonstrates good outcomes using the VAC device alone to achieve complete closure when applied immediately following debridement with frequent VAC changes.