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2011

Doping in sports

Articles 1 - 3 of 3

Full-Text Articles in Medicine and Health Sciences

Assessment Of Immune Function After Short-Term Administration Of Recombinant Human Growth Hormone In Healthy Young Males, Sandra B. Ramos, Ekua W. Brenu, Rhys Christy, A. Bon Gray, Lars Mcnaughton, Lotti Tajouri, Mieke Van Driel, Sonya M. Marshall-Gradisnik Sep 2011

Assessment Of Immune Function After Short-Term Administration Of Recombinant Human Growth Hormone In Healthy Young Males, Sandra B. Ramos, Ekua W. Brenu, Rhys Christy, A. Bon Gray, Lars Mcnaughton, Lotti Tajouri, Mieke Van Driel, Sonya M. Marshall-Gradisnik

Sonya Marshall-Gradisnik

Growth hormone (GH) is a commonly used drug aimed at improving sport performance. The aim of this study is to evaluate the immunomodulatory effects of short-term administration of recombinant GH (rhGH) in healthy young males. NK cell number, activity and phenotype, T cell number, CD4+ (Th1/Th2) cytokine production of IL2, IL4, IL6, IL10, TNF-a and IFN-y and CD4+/CD8+ ratio with particular attention to the possible correlation to IGF-I production were investigated. 30 males (27 ± 9 years) were randomly assigned to placebo (n = 15) or drug (rhGH) 1 mg/day groups (n = 15) with daily injection for 7 days. …


Assessment Of Immune Function After Short-Term Administration Of Recombinant Human Growth Hormone In Healthy Young Males, Sandra B. Ramos, Ekua W. Brenu, Rhys Christy, A. Bon Gray, Lars Mcnaughton, Lotti Tajouri, Mieke Van Driel, Sonya M. Marshall-Gradisnik Sep 2011

Assessment Of Immune Function After Short-Term Administration Of Recombinant Human Growth Hormone In Healthy Young Males, Sandra B. Ramos, Ekua W. Brenu, Rhys Christy, A. Bon Gray, Lars Mcnaughton, Lotti Tajouri, Mieke Van Driel, Sonya M. Marshall-Gradisnik

Lotti Tajouri

Growth hormone (GH) is a commonly used drug aimed at improving sport performance. The aim of this study is to evaluate the immunomodulatory effects of short-term administration of recombinant GH (rhGH) in healthy young males. NK cell number, activity and phenotype, T cell number, CD4+ (Th1/Th2) cytokine production of IL2, IL4, IL6, IL10, TNF-a and IFN-y and CD4+/CD8+ ratio with particular attention to the possible correlation to IGF-I production were investigated. 30 males (27 ± 9 years) were randomly assigned to placebo (n = 15) or drug (rhGH) 1 mg/day groups (n = 15) with daily injection for 7 days. …


Assessment Of Immune Function After Short-Term Administration Of Recombinant Human Growth Hormone In Healthy Young Males, Sandra B. Ramos, Ekua W. Brenu, Rhys Christy, A. Bon Gray, Lars Mcnaughton, Lotti Tajouri, Mieke Van Driel, Sonya M. Marshall-Gradisnik Sep 2011

Assessment Of Immune Function After Short-Term Administration Of Recombinant Human Growth Hormone In Healthy Young Males, Sandra B. Ramos, Ekua W. Brenu, Rhys Christy, A. Bon Gray, Lars Mcnaughton, Lotti Tajouri, Mieke Van Driel, Sonya M. Marshall-Gradisnik

A. Bon Gray

Growth hormone (GH) is a commonly used drug aimed at improving sport performance. The aim of this study is to evaluate the immunomodulatory effects of short-term administration of recombinant GH (rhGH) in healthy young males. NK cell number, activity and phenotype, T cell number, CD4+ (Th1/Th2) cytokine production of IL2, IL4, IL6, IL10, TNF-a and IFN-y and CD4+/CD8+ ratio with particular attention to the possible correlation to IGF-I production were investigated. 30 males (27 ± 9 years) were randomly assigned to placebo (n = 15) or drug (rhGH) 1 mg/day groups (n = 15) with daily injection for 7 days. …