Medicine and Health Sciences Commons^™

Merkel Cell Carcinoma Of The Skin, Patricia Tai, Edward Yu, Jon Tonita, James Gilchrist

Edward Yu

Background: Neuroendocrine/Merkel cell carcinoma (MCC) of the skin is an uncommon tumour. Currently, there are only limited data available on the natural history, prognostic factors, and patient management of MCC. Objective: To review our experience and build the largest database from the literature. Methods: Twenty-eight cases from the London Regional Cancer Center were combined with 633 cases obtained from the literature searched in English, French, German, and Chinese for the years 1966 to 1998. The database included age, sex, initial disease status at presentation to the clinic, site of primary, any coexisting disease, any previous irradiation, sizes of primary/nodal/distant metas-tases, …

Factor Analysis Of The Dsm-Iii-R Borderline Personality Disorder Criteria In Psychiatric Inpatients, Charles A. Sanislow, Carlos M. Grilo, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

Objective: The goal of this study was to examine the factor structure of the DSM-III-R criteria for borderline personality disorder in young adult psychiatric inpatients.

Method: The authors assessed 141 acutely ill inpatients with the Personality Disorder Examination, a semistructured diagnostic interview for DSM-III-R personality disorders. They used correlational analyses to examine the associations among the different criteria for borderline personality disorder and performed an exploratory factor analysis.

Results: Cronbach’s coefficient alpha for the borderline personality disorder criteria was 0.69. A principal components factor analysis with a varimax rotation accounted for 57.2% of the variance and revealed three homogeneous factors. …

Chemotherapy In Neuroendocrine/Merkel Cell Carcinoma Of The Skin: Case Series And Review Of 204 Cases, Patricia Tai, Edward Yu, Eric Winquist, Alex Hammond, Larry Stitt, Jan Tonita, Jim Gilchrist

Edward Yu

Purpose: To study the use of chemotherapy for Merkel cell carcinoma (MCC) of the skin. Patients and methods: Twenty-five cases of MCC were treated at the London Regional Cancer Center between 1987 and 1997. Thirteen cases treated with chemotherapy were reviewed with 191 cases from the literature. Results: At presentation, 24 patients had localized skin lesions (stage I) and one had locoregional involvement (stage II). Among the nine cases with recurrent nodal disease, six had chemotherapy as a component of salvage treatment. They were all free of disease at a median of 19 months (range, 12 to 37 months). In …

Radiation Treatment For Cervical Esophagus: Patterns Of Practice Study In Canada, 1996, Patricia Tai, Jake Van Dyk, Edward Yu, Jerry Battista, Matthew Schmid, Larry Stitt, Jon Tonita, Terry Coad

Edward Yu

PURPOSE: To assess the patterns of practice among Canadian radiation oncologists who treat esophageal cancers, using a trans-Canada survey, completed at the end of 1996. METHODS AND MATERIALS: One of 3 case presentations of different stages of cervical esophageal cancer was randomly assigned and sent to participating radiation oncologists by mail. Respondents were asked to fill in questionnaires regarding treatment techniques and to outline target volumes for the boost phase of radiotherapy. Radiation oncologists from 26 of 27 (96%) of all Canadian centers participated. RESULTS: High-energy X-rays (>/= 10 MV) were employed by 68% of the respondents in part …

Functional Infrared Imaging Of The Breast, J. Keyserlingk, P. Ahlgren, E. Yu, N. Belliveau, M. Yassa

Edward Yu

In order to re-assess the potential contribution of infrared (IR) imaging as a first-line component of a multi-imaging strategy using currently available technology, we first review the history of its introduction and clinical application, including the results of the Breast Cancer Detection Demonstration Projects (BCDDP). We then discuss experiments with a new high-resolution, computerized IR station and software program acquired by the Ville Marie Breast Center to assess IR imaging's ability to complement clinical examination and mammography in the early detection of breast cancer. Our goal is to show that high-resolution IR imaging provides additional safe, practical, and objective information …

The Collaborative Longitudinal Personality Disorders Study: Reliability Of Axis I And Ii Diagnoses., Mary C. Zanarini, Andrew E. Skodol, Donna S. Bender, Regina T. Dolan, Charles A. Sanislow, Elizabeth Schaefer, Leslie C. Morey, Carlos M. Grilo, M. Tracie Shea, Thomas H. Mcglashan, John G. Gunderson

Charles A. Sanislow, Ph.D.

Both the interrater and test-retest reliability of axis I and axis II disorders were assessed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and the Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV). Fair-good median interrater K (.40-.75) were found for all axis II disorders diagnosed five times or more, except antisocial personality disorder (1.0). All of the test-retest K for axis II disorders, except for narcissistic personality disorder (1.0) and paranoid personality disorder (.39), were also found to be fair-good. Interrater and test-retest dimensional reliability figures for axis II were generally higher than those for their categorical …

Verpleegkundiges Se Kommunikasie-Stimulasie Van Hoë-Risiko Babas In Die Neonatale Sorgeenheid : Oorsig, Elmien Kraamwinkel, Brenda Louw

Brenda Louw

Relation Of Therapeutic Alliance And Perfectionism To Outcome In Brief Outpatient Treatment Of Depression, David C. Zuroff, Sidney J. Blatt, Stuart M. Sotsky, Janice L. Krupnick, Daniel J. Martin, Charles A. Sanislow, Sam Simmens

Charles A. Sanislow, Ph.D.

Prior analyses of the National Institute of Mental Health Treatment of Depression Collaborative Research Program demonstrated that perfectionism was negatively related to outcome, whereas both the patient's perception of the quality of the therapeutic relationship and the patient contribution to the therapeutic alliance were positively related to outcome across treatment conditions (S. J. Blatt, D. C. Zuroff, D. M. Quinlan, & P. A. Pilkonis, 1996; J. L. Krupnick et al., 1996). New analyses examining the relations among perfectionism, perceived relationship quality, and the therapeutic alliance demonstrated that (a) the patient contribution to the alliance and the perceived quality of the …

Alcohol Consumption And Risk Of Coronary Heart Disease By Diabetes Status, Paulo A. Lotufo

Paulo A Lotufo

Background—An inverse association between moderate alcohol consumption and coronary heart disease (CHD) has been observed in several epidemiological studies. To assess whether a similar association exists among diabetics, we examined the relation between light to moderate alcohol consumption and CHD in men with and without diabetes mellitus in a prospective cohort study. Methods and Results—A total of 87 938 US physicians (2790 with diagnosed diabetes mellitus) who were invited to participate in the Physicians’ Health Study and were free of myocardial infarction, stroke, cancer, or liver disease at baseline were followed for an average of 5.5 years for death with …

Short And Long-Term Effects Of Medication And Psychotherapy In The Brief Treatment Of Depression: Further Analyses Of Data From The Nimh Tdcrp, Sidney J. Blatt, David C. Zuroff, Colin M. Bondi, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

Prior analyses of data from the NIMH sponsored Treatment for Depression Collaborative Research Program (TDCRP; e.g., I. Elkin, 1994) indicated greater reduction of symptoms at midtreatment (8th wk) with Imipramine (IMI-CM) than with Cognitive-behavioral therapy (CBT) and Interpersonal therapy (IPT), but no significant differences in symptom reduction among these 3 active treatments at termination. Current analyses of previously unanalyzed data from ratings by therapists, clinical evaluators, and 162 patients (mean age 35 yrs) at termination and at 18-mo follow-up also indicated no significant differences among these treatments in symptom reduction or ratings of current clinical condition. But significant treatment differences …

Canadian Medical Officers In The Royal Navy -- World War Ii By Harry Stafford Morton., Vivian C. Mcalister

Vivian C. McAlister

CANADIAN MEDICAL OFFICERS IN THE ROYAL NAVY -- WORLD WAR II. Harry Stafford Morton. 112 pp. Illust. Canadian Naval Memorial Trust, HMCS Sackville, PO Box 99000, Stn Forces, Halifax NS B3K 5X5. 2000. Can$18.00

At the beginning of the Second World War, the Royal Canadian Navy offered 90 medical officers on loan to the Royal Navy. The author was among that group, which included leaders in Canadian surgery such as Surgeon Lieutenant McLachlin of London, Ont. The history of these medical officers has not been written because it fell between histories of the Royal Canadian Navy and the Royal Navy. …

Sirolimus-Tacrolimus Combination Immunosuppression., Vivian C. Mcalister, Zu-Hua Gao, Kevork Peltekian, Javier Domingues, Kamran Mahalati, Allan S. Macdonald

Vivian C. McAlister

A series of 32 recipients of liver, kidney, or pancreas transplants who were treated with sirolimus and low-dose tacrolimus experienced a low rate of rejection and excellent graft function without drug-related toxic effects.

Altered Fractionation Of Radical Radiation Therapy In The Management Of Unresectable Non-Small Cell Lung Cancer, E. Yu, K. Lochrin, P. Dixon, Y. Ung, A. Gagliardi, W. K. Evans

Edward Yu

No abstract provided.