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Full-Text Articles in Medicine and Health Sciences

Incremental Dialysis For Preserving Residual Kidney Function—Does One Size Fit All When Initiating Dialysis?, A. T. Mathew, Y. Obi, C. M. Rhee, J. A. Chou, K. Kalantar-Zadeh Dec 2017

Incremental Dialysis For Preserving Residual Kidney Function—Does One Size Fit All When Initiating Dialysis?, A. T. Mathew, Y. Obi, C. M. Rhee, J. A. Chou, K. Kalantar-Zadeh

Journal Articles

© 2018 Wiley Periodicals, Inc. While many patients have substantial residual kidney function (RKF) when initiating hemodialysis (HD), most patients with end stage renal disease in the United States are initiated on 3-times per week conventional HD regimen, with little regard to RKF or patient preference. RKF is associated with many benefits including survival, volume control, solute clearance, and reduced inflammation. Several strategies have been recommended to preserve RKF after HD initiation, including an incremental approach to HD initiation. Incremental HD prescriptions are personalized to achieve adequate volume control and solute clearance with consideration to a patient's endogenous renal function. …


Glecaprevir And Pibrentasvir For 12 Weeks For Hepatitis C Virus Genotype 1 Infection And Prior Direct-Acting Antiviral Treatment, F. Poordad, F. Felizarta, A. Asatryan, M. S. Sulkowski, R. W. Reindollar, C. S. Landis, S. C. Gordon, S. L. Flamm, D. E. Bernstein, F. J. Mensa, +6 Additional Authors Jan 2017

Glecaprevir And Pibrentasvir For 12 Weeks For Hepatitis C Virus Genotype 1 Infection And Prior Direct-Acting Antiviral Treatment, F. Poordad, F. Felizarta, A. Asatryan, M. S. Sulkowski, R. W. Reindollar, C. S. Landis, S. C. Gordon, S. L. Flamm, D. E. Bernstein, F. J. Mensa, +6 Additional Authors

Journal Articles

No abstract provided.


Neurovascular Unit Dysfunction And Blood-Brain Barrier Hyperpermeability Contribute To Schizophrenia Neurobiology: A Theoretical Integration Of Clinical And Experimental Evidence, S. Najjar, S. Pahlajani, V. De Sanctis, J. N.H. Stern, A. Najjar, D. Chong Jan 2017

Neurovascular Unit Dysfunction And Blood-Brain Barrier Hyperpermeability Contribute To Schizophrenia Neurobiology: A Theoretical Integration Of Clinical And Experimental Evidence, S. Najjar, S. Pahlajani, V. De Sanctis, J. N.H. Stern, A. Najjar, D. Chong

Journal Articles

No abstract provided.


Combined-Modality Hypofractionated Radiotherapy For Elderly Patients With Glioblastoma: Setting A New Standard., B. A. Vellayappan, L. M. Halasz, J. P. S. Knisely, E. L. Chang, S. S. Lo Jan 2017

Combined-Modality Hypofractionated Radiotherapy For Elderly Patients With Glioblastoma: Setting A New Standard., B. A. Vellayappan, L. M. Halasz, J. P. S. Knisely, E. L. Chang, S. S. Lo

Journal Articles

No abstract provided.


Novel Wavelet-Based Segmentation Of Prostate Cbct Images With Implanted Calypso Transponders., Y. Liu, Z. Saleh, Y. Song, M. Chan, X. Li, C. Shi, X. Qian, X. Tang Jan 2017

Novel Wavelet-Based Segmentation Of Prostate Cbct Images With Implanted Calypso Transponders., Y. Liu, Z. Saleh, Y. Song, M. Chan, X. Li, C. Shi, X. Qian, X. Tang

Journal Articles

Segmentation of prostate Cone Beam CT (CBCT) images is an essential step towards real-time adaptive radiotherapy (ART). It is challenging for Calypso patients, as more artifacts generated by the beacon transponders are present on the images. We herein propose a novel wavelet-based segmentation algorithm for rectum, bladder, and prostate of CBCT images with implanted Calypso transponders. For a given CBCT, a Moving Window-Based Double Haar (MWDH) transformation is applied first to obtain the wavelet coefficients. Based on a user defined point in the object of interest, a cluster algorithm based adaptive thresholding is applied to the low frequency components of …


Microtubule-Targeting Agents Can Sensitize Cancer Cells To Ionizing Radiation By An Interphase-Based Mechanism, D. Markowitz, G. Ha, R. Ruggieri, M. Symons Jan 2017

Microtubule-Targeting Agents Can Sensitize Cancer Cells To Ionizing Radiation By An Interphase-Based Mechanism, D. Markowitz, G. Ha, R. Ruggieri, M. Symons

Journal Articles

No abstract provided.


Repurposing Mebendazole As A Replacement For Vincristine For The Treatment Of Brain Tumors, M. De Witt, A. Gamble, D. Hanson, D. Markowitz, C. Powell, S. Al Dimassi, M. Atlas, J. Boockvar, R. Ruggieri, M. Symons Jan 2017

Repurposing Mebendazole As A Replacement For Vincristine For The Treatment Of Brain Tumors, M. De Witt, A. Gamble, D. Hanson, D. Markowitz, C. Powell, S. Al Dimassi, M. Atlas, J. Boockvar, R. Ruggieri, M. Symons

Journal Articles

No abstract provided.


Long-Term Outcome Of 487 Patients With Early-Stage Extra-Nodal Marginal Zone Lymphoma, S. Teckie, S. Qi, M. Chelius, S. Lovie, M. Hsu, A. Noy, C. Portlock, J. Yahalom Jan 2017

Long-Term Outcome Of 487 Patients With Early-Stage Extra-Nodal Marginal Zone Lymphoma, S. Teckie, S. Qi, M. Chelius, S. Lovie, M. Hsu, A. Noy, C. Portlock, J. Yahalom

Journal Articles

No abstract provided.


The More Igrt Systems, The Merrier?, B. Sun, J. Chang, Y. Rong Jan 2017

The More Igrt Systems, The Merrier?, B. Sun, J. Chang, Y. Rong

Journal Articles

No abstract provided.


Screening For Depression In Cancer Patients Receiving Radiotherapy: Feasibility And Identification Of Effective Tools In The Nrg Oncology Rtog 0841 Trial, L. I. Wagner, S. L. Pugh, W. Small, J. Kirshner, K. Sidhu, M. J. Bury, A. S. Denittis, T. E. Alpert, B. F. Bloom, D. W. Bruner, +6 Additional Authors Jan 2017

Screening For Depression In Cancer Patients Receiving Radiotherapy: Feasibility And Identification Of Effective Tools In The Nrg Oncology Rtog 0841 Trial, L. I. Wagner, S. L. Pugh, W. Small, J. Kirshner, K. Sidhu, M. J. Bury, A. S. Denittis, T. E. Alpert, B. F. Bloom, D. W. Bruner, +6 Additional Authors

Journal Articles

No abstract provided.


Anesthesia Duration As An Independent Risk Factor For Early Postoperative Complications In Adults Undergoing Elective Acdf., K. Phan, J. S. Kim, J. H. Kim, S. Somani, J. Di'capua, J. E. Dowdell, S. K. Cho Jan 2017

Anesthesia Duration As An Independent Risk Factor For Early Postoperative Complications In Adults Undergoing Elective Acdf., K. Phan, J. S. Kim, J. H. Kim, S. Somani, J. Di'capua, J. E. Dowdell, S. K. Cho

Journal Articles

Study Design: Retrospective study.

Objective: To determine the presence of any potential associations between anesthesia time with postoperative outcome and complications following elective anterior cervical discectomy and fusion (ACDF).

Methods: Patients who underwent elective ACDF were identified in the American College of Surgeons National Quality Improvement Program database. Patient demographics, medical comorbidities, and perioperative and postoperative complications up to 30 days were analyzed by univariate and multivariate analysis.

Results: A total of 3801 patients undergoing elective ACDF were identified. Patients were subdivided into quintiles of anesthesia time: Group 1, 48 to 129 minutes (n = 761, 20%); Group 2, 129 …


Developing And Implementing A Multisource Feedback Tool To Assess Competencies Of Emergency Medicine Residents In The United States., J. Lamantia, L. M. Yarris, K. Sunga, M. Weizberg, D. Hart, G. Farina, E. Rodriguez, R. Lucas, Z. Mahmooth, J. Lockyear, +1 Additional Author Jan 2017

Developing And Implementing A Multisource Feedback Tool To Assess Competencies Of Emergency Medicine Residents In The United States., J. Lamantia, L. M. Yarris, K. Sunga, M. Weizberg, D. Hart, G. Farina, E. Rodriguez, R. Lucas, Z. Mahmooth, J. Lockyear, +1 Additional Author

Journal Articles

Objectives: Multisource feedback (MSF) has potential value in learner assessment, but has not been broadly implemented nor studied in emergency medicine (EM). This study aimed to adapt existing MSF instruments for emergency department implementation, measure feasibility, and collect initial validity evidence to support score interpretation for learner assessment. Methods: Residents from eight U.S. EM residency programs completed a self-assessment and were assessed by eight physicians, eight nonphysician colleagues, and 25 patients using unique instruments. Instruments included a five-point rating scale to assess interpersonal and communication skills, professionalism, systems-based practice, practice-based learning and improvement, and patient care. MSF feasibility was measured …


Nfatc3 And Vip In Idiopathic Pulmonary Fibrosis And Chronic Obstructive Pulmonary Disease, A. M. Szema, E. Forsyth, B. Ying, S. A. Hamidi, J. J. Chen, S. Hwang, J. C. Li, D. S. Dwyer, J. M. Ramiro-Diaz, L. V. Gonzalez Bosc, +1 Additional Author Jan 2017

Nfatc3 And Vip In Idiopathic Pulmonary Fibrosis And Chronic Obstructive Pulmonary Disease, A. M. Szema, E. Forsyth, B. Ying, S. A. Hamidi, J. J. Chen, S. Hwang, J. C. Li, D. S. Dwyer, J. M. Ramiro-Diaz, L. V. Gonzalez Bosc, +1 Additional Author

Journal Articles

No abstract provided.