Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Differential Effects Of Isoflurane And Propofol Anesthesia On Neurogenesis In Young And Aged Rats, Diana Marcela Erasso Jan 2011

Differential Effects Of Isoflurane And Propofol Anesthesia On Neurogenesis In Young And Aged Rats, Diana Marcela Erasso

USF Tampa Graduate Theses and Dissertations

Worldwide, millions of young and elderly patients receive procedures that could not be performed without the use of anesthetics. Unfortunately, emerging animal and human data suggest an association between exposure to general anesthesia and impairment of cognitive function in pediatric and geriatric patients. Recent laboratory data have shown that general anesthetics are potentially damaging to the developing and aging brain. However, the mechanism by which this happens is still unknown. General anesthetics affect learning and memory, a brain function involving neural plasticity. An important form of neural plasticity receiving attention is postnatal neurogenesis. This process is highly regulated and involved …


Nitrous Oxide Anesthesia In Children For Mri: A Comparison With Isoflurane And Halothane, Mehmet Emi̇n Orhan, Ferruh Bi̇lgi̇n, Oğuz Kiliçkaya, Abdulkadi̇r Atim, Ercan Kurt Jan 2011

Nitrous Oxide Anesthesia In Children For Mri: A Comparison With Isoflurane And Halothane, Mehmet Emi̇n Orhan, Ferruh Bi̇lgi̇n, Oğuz Kiliçkaya, Abdulkadi̇r Atim, Ercan Kurt

Turkish Journal of Medical Sciences

To compare the anesthetic effects of nitrous oxide, isoflurane, and halothane on hemodynamic stability and recovery characteristics in pediatric patients during magnetic resonance imaging (MRI). Materials and methods: The present study includes 60 ASA I-II children aged 1-12 years undergoing MRI. After endotracheal intubation, patients were randomly assigned into 1 of 3 anesthetic groups. Group N (n = 20) received nitrous oxide and oxygen (N_2O:O_2 60:40), Group I (n = 20) received 0.5% isoflurane and oxygen, Group H (n = 20) received 0.5% halothane and oxygen to maintain anesthesia. At the completion of the procedure, inhalation anesthetic was discontinued. Extubation, …