Medicine and Health Sciences Commons^™

Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions Of Src Family Tyrosine Kinases To Feeding Triggered Either By Nmda Injection Or By Food Deprivation, Arshad Khan, Herman H. Cheung, Elizabeth R. Gillard, Jennifer A. Palarca, Derek S. Welsbie, James W. Gurd, B. Glenn Stanley

Arshad M. Khan, Ph.D.

No abstract provided.

Biochemical Enrichment And Biophysical Characterization Of A Taste Receptor For L-Arginine From The Catfish, Ictalurus Puntatus., William Grosvenor, Yuri Kaulin, Andrew I Spielman, Douglas L Bayley, D Lynn Kalinoski, John H Teeter, Joseph G Brand

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: The channel catfish, Ictalurus punctatus, is invested with a high density of cutaneous taste receptors, particularly on the barbel appendages. Many of these receptors are sensitive to selected amino acids, one of these being a receptor for L-arginine (L-Arg). Previous neurophysiological and biophysical studies suggested that this taste receptor is coupled directly to a cation channel and behaves as a ligand-gated ion channel receptor (LGICR). Earlier studies demonstrated that two lectins, Ricinus communis agglutinin I (RCA-I) and Phaseolus vulgaris Erythroagglutinin (PHA-E), inhibited the binding of L-Arg to its presumed receptor sites, and that PHA-E inhibited the L-Arg-stimulated ion conductance …

Ionizing Radiation And Endostatin Gene Therapy Against Lung Tumor, Xian Luo

Loma Linda University Electronic Theses, Dissertations & Projects

Although many advances have been made in radiotherapy, tumor radioresistance and normal tissue damage continue to always be important issues for radiation oncologists. Numerous reports have also documented that radiation exposure increases the risk for malignancy and suppresses immune mechanisms. However, increasing evidence has suggested that anti-angiogenic therapy that targets tumor blood supply may alter abnormal tumor vasculature, thus synergizing radiotherapy. The governing hypothesis of the present study was that modification of tumor vasculature by antiangiogenic gene therapy can increase the efficacy of radiotherapy and that radiation can also improve DNA transfection efficiency by increasing expression of the administered gene. …

Update - March 2004, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Christians Contemplating New Developments in Biomedicine
-- Editorial
-- Christian Principals of Genetic Intervention
-- Statement on Ethical Considerations Regarding Human Cloning
-- Honoring the Religious Impulse Within the Arena of Genetic Counseling

Detection And Mapping Of Quantitative Trait Loci That Determine Responsiveness, Janet L. Mueller, E. A. Ellenberger, Linda K. Vaughn, John K. Belknap, Raymond M. Quock

Biomedical Sciences Faculty Research and Publications

Exposure to 70% N₂O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N₂O. Offspring from the F₂ generation bred from B6 and D2 progenitors exhibited a broad range of responsiveness to N₂O antinociception as determined by the acetic acid-induced abdominal constriction test. QTL analysis was then used to dissect this continuous trait distribution into component loci, and to map them to broad chromosomal regions. To this end, …

Health Professions Division Catalog 2004-2005, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Asymmetric Maxillary First Molar Distalization With The Transpalatal Arch, Serhat Eyüboğlu, Ali̇ Osman Bengi̇, Ari̇f Ümi̇t Gürton, Erol Akin

Turkish Journal of Medical Sciences

The purpose of this study was to determine the dentoalveolar and skeletal effects of a Goshgarian transpalatal arch (TPA) in unilateral maxillary first molar distalization. The treatment group consisted of 15 patients (6 females and 9 males) between 10.8 and 12.1 years of age. The maxillary first molars, which were in a dental Class I relationship (anchorage molars), were the anchorage units, while the molars in Class II relationship (distalized molars) were distalized using a TPA with 150 g. of force. Lateral head films, study models and clinical photographs of all the patients were taken before and after distalization. The …

Evaluation Of Pulsed Electromagnetic Fields On Bone Healing After Implant Placement In The Rabbit Mandibular Model, Jüli̇de Özen, Arzu Atay, Selçuk Oruç, Mehmet Dalkiz, Bedri̇ Beydemi̇r, Sali̇h Develi̇

Turkish Journal of Medical Sciences

Although bone healing around titanium implants has already been evaluated, the effect of pulsed electromagnetic fields (PEMF) during the period of bone maturation around titanium dental implants has not yet been investigated. The aim of this study was to evaluate the effects of PEMFs on bone formation following the insertion of titanium-dental implants in the rabbit mandibular model. Ti-6Al-4V (Sulzer Calcitek, California, USA) dental implants were inserted into the mandibulae of 28 New Zealand rabbits (6 weeks old). Fourteen were stimulated with PEMFs for 2 consecutive weeks, 4 h/day, at a magnetic intensity of 0.2 milli Tesla (mT), while the …

Reconstruction Of Localized Defects Of The Anterior Maxillary Ridge With Autogenous Bone Graft Before Insertion Of A Single Implant, Yilmaz Günaydin, Yavuz Si̇nan Aydintuğ, Keri̇m Ortakoğlu, Meti̇n Şençi̇men, Mehmet Dalkiz

Turkish Journal of Medical Sciences

ÜNAYDIN^1, Yavuz Sinan AYDINTUĞ^1, Kerim ORTAKOĞLU^1, Metin ŞENÇİMEN^1, Mehmet DALKIZ^2 ^1Department of Oral and Maxillofacial Surgery, Gülhane Military Medical Academy, Ankara - Turkey ^2Department of Prosthetic Dentistry, Gülhane Military Medical Academy, Ankara - Turkey

Molecular Genetic Investigation Of Autosomal Dominant Hemifacial Microsomia, Rebecca Watt

Theses: Doctorates and Masters

The overall purpose of this project was to explore the underlying pathogenesis of Hemifacial microsomia (HFM), investigate treatment and management options identify likely candidate genes and screen candidate genes for mutation(s) causing the form of HFM segregating on chromosome 11 in a West Australian family. Hemifacial microsomia is a congenital malformation arising from the derivatives of the first and second branchial arches. It is both clinically and genetically heterogeneous and can occur sporadically or segregate within families in an autosomal fashion. HFM is characterised by significant undergrowth to one side of the face and is a common birth defect with …