Medicine and Health Sciences Commons^™

Testing The Effect Of Acetaminophen Overdose On The Liver And The Role Of Biomarkers To Predict Death Or Survival, Christine Brasic

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Animal-Assisted With Nursing Home Residents, Kierstyn Stevens

Scholars Week

This study was conducted to evaluate the use of animal-assisted therapy in nursing home residents, particularly a Nursing and Rehabilitation center in Paducah, KY. Residents of long term care facilities, like a nursing home, face many challenges due to physical and mental changes. Factors contributing to these changes may include financial changes, loss of autonomy, mobility changes, etc. Various articles concerning animal-assisted therapy in elders, residents of hospitals, and residents of long-term care facilities were gathered to examine potential benefits. Findings indicated significant improvement in variables found often in elders, such as anxiety, depression, aggression, and loneliness. Many of these …

International Conference Medicine And Nursing, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 9th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

Crnas And Sugammadex Use: A Qualitative Analysis, Natalia Izquierdo Bsn, Rn, Emily Mancewicz Bsn, Rn

Grace Peterson Nursing Research Colloquium

Background: The availability of Sugammadex has increased options for Certified Registered Nurse Anesthetists’ (CRNAs) and their choice of neuromuscular reversal agents, however administration is impacted by a variety of provider and institutional factors.

Objectives: The purpose of this study was to examine and describe the personal and institutional factors impacting the use of Sugammadex in Illinois by CRNAs.

Method: A qualitative study design using an open-ended survey yielded 209 responses. The three main themes that emerged were 1) Why CRNAs choose to use or avoid Sugammadex 2) How CRNAs dose Sugammadex and 3) Practice variations existing within the clinical setting. …

A Mathematical Model To Explore The Potential Of Combinations Of Adt And Immunotherapies, Johnna Barnaby

Biology and Medicine Through Mathematics Conference

No abstract provided.

Similac Special Care And Elecare Cause Neonatal Gut Injury In Mice, Karishma Rao, Heather L. Menden, Wei Yu, Inamul Haque, Susana Chavez-Bueno, Alain C. Cuna, Shahid Umar, Venkatesh Sampath

Research Days

No abstract provided.

Clinical Validation And Diagnostic Rate/Outcomes Of A Dual Molecular Diagnostic Assay For Myotonic Dystrophy 1., Maxime Cadieux-Dion, Isabelle Thiffault, Midhat S. Farooqi, Joseph Alaimo

Research Days

No abstract provided.

A Reinforcement Learning Based Control Approach For Propofol-Induced Burst Suppression, Jason C. Huang, Scott C. Tadler, Brian J. Mickey, Keith Jones

Utah Space Grant Consortium

High-dose propofol is being investigated for its potential antidepressant effect. Propofol is titrated to induce burst suppression, a specific EEG pattern. However, propofol is difficult to dose due to uncertainty in each patient’s pharmacokinetics (PK) and pharmacodynamics (PD), and the lack of a commercially available monitor of propofol concentration. Clinicians currently infer the proper drug dose after observing the EEG response to the given dose. In this report we share our development of an automated controller to optimally administer propofol-induced burst suppression. We designed a deep deterministic policy gradient (DDPG) algorithm, which includes two deep neural networks and relates a …

452— Potential Impacts Of Basic Reproduction Number On The Covid-19 Epidemic, Marisa Presutto

GREAT Day Posters

The basic reproduction number (R₀) of a disease can be thought of as the number of cases that one case will directly generate if the rest of the population is susceptible to infection. The R₀ of COVID-19 has recently become clearer; toward the beginning of the outbreak, the Imperial College Group estimated it to be somewhere between 1.5 and 3.5 (Imai et al. 2020), but they have now assumed a value of 2.4 (Ferguson et al. 2020). Using the Watts-Strogatz small-world model, I examined the effects of different R₀ values within the original range on the …

Outcomes Of Neuropace Rns Vs Surgery Among Patients With Epilepsy In Eloquent Foci, Erica Hartmann

Galileo-W Conference

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Say What You Mean To Say: Unpacking The Complexities Of Communication Between Patients And Their Providers, Kate Timony

Galileo-W Conference

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A Comparative Policy Analysis Of The United Kingdom And India Regarding The Reuse Of Medical Devices., Shamaa Vora

Galileo-W Conference

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Hospital Characteristics And Hospital Acquired Infections In The United States, Cassidy Prewitt

Galileo-W Conference

Cassidy Prewitt's Oral Presentation given at the 2020 APHA Annual Meeting

"APHA's Annual Meeting and Expo is the largest and most influential annual gathering of public health professionals."

View the Presentation HERE

Submit a Question for Cassidy

Tetralogy Of Fallot: A Clinical Review, Jacob Wooten, Joshua Bahos Silva

Student Scholar Showcase

Tetralogy of Fallot is a congenital heart disease that is associated with structural abnormalities during fetal development 1. The incidence of Tetralogy of Fallot in the United States is approximately 3-5 cases per 10,000 live births and is considered one of the most common cyanotic congenital heart diseases 2. The exact etiology of Tetralogy of Fallot is unknown, however it is thought to be associated with untreated maternal diabetes, maternal use of retinoids, as well as chromosomal abnormalities 2. The main components of this disease state include a right ventricular outflow obstruction, interventricular communication in the form of a ventricular …

Apple Cider Vinegar Weight Loss Drinks On Pinterest, Sydney Chamberlain, Jana Mitchell, Davis Major, Lena Elimam, Cassandra Cleland

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Background: More than a third of adults in the U.S. are currently trying to lose weight. Social media, specifically Pinterest with more than 322 million users, has changed the way people seek health information specifically weight loss. Apple cider vinegar has shown great promise for weight loss in controlled lab settings, yet these claims are widely shared on social media and may not yield the same benefits.

Purpose: This study used directed content analysis to examine how apple cider vinegar weight loss drinks were portrayed on Pinterest, a social media website used to bookmark online content. Methods: Using the search …

Regenerative Medicine Therapy: Adipose Derived Extracellular Vesicles In Viral Myocarditis, David Gorelov, Damian N. Di Florio, Gary R. Salomon, Angita Jain, Nick E. Saikaili, Danielle J. Beetler, Swikriti Shrestha, Ming Tian, Joy Wolfram Phd, Delisa Fairweather Phd, Katelyn Bruno Phd, Judith D. Ochrietor Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Objective: Myocarditis, inflammation of the heart muscle, is an autoimmune heart disease that can be caused by viruses, bacteria and toxins. Myocarditis can lead to dilated cardiomyopathy (DCM) and heart failure. Currently there are no disease-specific therapies for treating myocarditis or preventing progression to DCM. Adipose Extracellular Vesicles (AEVs) are lipid bilayer nanoparticles that are released into the outside environment of adipocytes and provide promising regenerative potential for inflammatory diseases like myocarditis.

Methods: Lipoaspirate was obtained from women and men and AEVs isolated from the lipoaspirate using tangential flow filtration. We injected wild type male BALB/c mice with 250uL AEVs …

Using Active Learning To Build A Foundation For Bioinformatics Training., Stacey E. Wahl Ph.D., Amy L. Olex Ms

Transforming Libraries for Graduate Students

As Health Sciences Libraries evolve, the support they offer graduate students has evolved to incorporate many aspects of the research life cycle. At Tompkins-McCaw Library for the Health Sciences, we have partnered with the Wright Center for Clinical and Translational Research to offer training workshops for graduate students who are interested in using bioinformatics to plan, analyze, or execute scientific experiments. We offer two series: 1) an 8-week, 1-hour per week seminar series providing a general overview of available techniques and 2) a week-long intensive, two hours per session, series on utilizing free databases from the National Center for Biotechnology …

Students As Investigators: Utilizing Active Learning To Engage Genetic Counseling Students, Stacey E. Wahl Ph.D., Dana L. Ladd Ph.D.

Transforming Libraries for Graduate Students

Providing one-shot instruction sessions can be difficult, particularly in the graduate learning environment. As librarians, we want to provide students with the skills to search effectively for health information without overwhelming or confusing them. In health science graduate programs, we are expected to connect literature searching skills with the content of the courses in a manner that is engaging to students. This challenge can be exacerbated when students are new to graduate school and have not yet become familiar with scientific literature searching or the research process. Two medical librarians sought to overcome these challenges by empowering genetic counseling students …

Utilizing Chemical Mutagenesis To Determine U21 Mechanism Of Action In Toxoplasma Gondii, Andrew Pham

UNO Student Research and Creative Activity Fair

The abstract has been removed to protect intellectual property of the project.

Longitudinal Analysis Of Gait In People With Parkinson’S Disease To Improve The Detection Of Risk Of Falls, Ryan Meidinger

UNO Student Research and Creative Activity Fair

Within 3 years of diagnosis, more than 85% of people with Parkinson’s disease (PD) develop gait problems, which may lead to falls resulting in serious injury and reduced quality of life. The evolution of gait impairments with PD progression and the relationship between locomotor performance and falls in PD are unclear. In addition, large individual variations exist at the level of gait performances corresponding to specific levels of disease severity. Deficits in cognitive and sensory-motor functions in PD also impair the ability to walk while doing another task (i.e., dual-tasking). When attentional resources in PD patients are allocated to more …

Oral Contraceptives As Possible Acl Injury Prevention Method, Haley Schweizer

Capstone Showcase

ABSTRACT

Introduction: Anterior Cruciate Ligament (ACL) injuries are an upsetting setback for many athletes that require a long and costly recovery process. The injury rates are four times greater in women than men. Preventative measures that help to prevent ACL injuries are limited to stretching and strengthening. Therefore, this review aims to investigate if oral contraceptive [I] usage provides a possible new avenue for prevention of ACL injury [O] in young female athletes (ages 18-30) [P] compared to those that do not take oral contraceptives [C].

Methods: A literature review was performed though PubMed, Google Scholar, SCOPUS Database, and ClinicalKey …

Manipulation Of Ar-V7 In Castrate Resistant Prostate Cancer, Sean Simpson

Capstone Showcase

Abstract

Introduction: Prostate cancer is the leading cancer affecting men of all races in the United States, and the second leading cause of cancer death in men. If caught early, many have had success in combating the disease, but if the cancer metastasizes, the 5-year survival rate drops to only 30%. Current treatment options heavily involve hormone therapy, radiation therapy, chemotherapy, and surgery. While these treatments can be effective for early stage prostate cancer, they can fall short in preventing the spread of the cancer to other parts of the body. This review analyzes a new potential way of preventing …

The Efficacy Of Ketamine In Adult Patients With Obsessive Compulsive Disorder With Symptoms Refractory To Standard Of Care Treatment., Brooke Thornton

Capstone Showcase

First line pharmacologic treatments for adult patients with Obsessive Compulsive Disorder (OCD) involve selective serotonin/norepinephrine reuptake inhibitors (SSRI/SNRIs). These drug classes often fail to deliver timely relief of symptoms as well as maintain longevity of symptom recurrence. This research analyzed the use of ketamine in adult patients suffering with OCD for the purposes of more efficacious management of symptoms. Although ketamine demonstrated a timelier relief of symptoms in some small clinical studies, its effects were ultimately unable to be sustained long term. Additionally, a wide range of adverse effects including dissociation, and rebound symptoms were observed. As a result, large …

The Comparative Efficacy Of Amantadine Vs. Lcig Therapy For The Treatment Of Levodopa-Induced Dyskinesia In Patients With Advanced Parkinson's Disease, Katelynn Timony

Capstone Showcase

Introduction: Though levodopa-carbidopa therapy remains the gold standard of Parkinson’s disease (PD) treatment to this day, patients often experience increased dyskinetic activity as a result of long-term treatment; known as levodopa-induced dyskinesia (LID); the mechanism of which is not completely understood. In this review, the efficacy of two adjunct treatments for LID are compared: 1) the concomitant administration of amantadine, an antiviral medication with antidyskinetic properties; and 2) a new form of levodopa administration in the form of an intestinal gel delivered straight via a device much like an insulin pump.

Methods: Two systematic literature searches of primary, peer-reviewed articles …

Ketamine Vs Placebo For Depression, Austin Strosser

Capstone Showcase

Depression is a disease that effects millions of patients and has a variety of symptoms. It is primarily defined by depressed mood and anhedonia. The first line treatment for depression is SSRI medications. These medications have several side effects and are not effective for a large number of patients. Therefore, this study was done to review ketamine as a new treatment option for depression and see how it compares to a placebo.

The Efficacy Of Aquablation In The Treatment Of Large Volume Benign Prostatic Hypertrophy, Jessica Greenwood

Capstone Showcase

Introduction:

Benign Prostatic Hypertrophy (BPH) is a condition affecting adult males causing symptoms including urinary frequency, incontinence, and urinary retention. While first line treatment methods include lifestyle modifications and pharmacologic therapies, many patients elect for surgical procedures for symptomatic relief. In patients with extremely large volume prostates the surgical method most commonly used has been an open prostatectomy, which is associated with both long-term efficacy and more surgical complications than minimally invasive techniques. Therefore, this review analyzes Aquablation (I) for symptom management (O) in patients diagnosed with BPH (P) compared to open prostatectomy (C).

Methods:

A literature search was conducted …

Delayed Umbilical Cord Clamping (Dcc) Compared To Early Cord Clamping (Ecc) In Preterm Infants, Madelynn Fretto

Capstone Showcase

Early cord clamping (ECC) versus delayed cord clamping (DCC) has been studied in preterm infants. The question that was researched is, in pregnant women who are giving birth [P], does delayed umbilical cord clamping (DCC) [I] as compared to early cord clamping [C] improve outcome of preterm infants born before 37 weeks gestation [O]? Results showed preterm infants with DCC had increased hematocrit and hemoglobin, decreasing their risk of anemia. There was not a significant difference in the incidence of jaundice between the two groups. Results suggested DCC has long-term neuroprotective effects. There were no significant differences in intraventricular hemorrhage …