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Full-Text Articles in Medicine and Health Sciences
The Efficacy And Safety Of Targeted Narrowband Uvb Therapy: A Retrospective Cohort Study, Kübra Esen Salman, İlknur Altunay, Andaç Salman
The Efficacy And Safety Of Targeted Narrowband Uvb Therapy: A Retrospective Cohort Study, Kübra Esen Salman, İlknur Altunay, Andaç Salman
Turkish Journal of Medical Sciences
Background/aim: Phototherapy is a safe and effective treatment modality for numerous dermatological conditions. Recently, targeted phototherapy modalities have gained importance due to their advantages over conventional phototherapy.This retrospective study aimed to evaluate the safety and efficacy of targeted narrowband UVB phototherapy in patients with dermatological disorders.Materials and methods: This single-center study included 173 patients who were treated with targeted narrowband UVB phototherapy. Demographic features, phototherapy parameters, and adverse effects were evaluated in all patients, and the treatment response was assessed in patients who attended at least one follow-up visit. Results: A total of 173 patients (102 females; 71 males) with …
Association Of Serum Cortisol And Dehydroepiandrosterone Sulfate (Dheas) Levels With Psychological Stress In Patients With Vitiligo, Ahmet Gurpinar, Si̇bel Doğan Günaydin, Cengi̇z Kiliç, Ayşen Karaduman
Association Of Serum Cortisol And Dehydroepiandrosterone Sulfate (Dheas) Levels With Psychological Stress In Patients With Vitiligo, Ahmet Gurpinar, Si̇bel Doğan Günaydin, Cengi̇z Kiliç, Ayşen Karaduman
Turkish Journal of Medical Sciences
Background/aim: Vitiligo is a depigmentation disorder that leads to serious psychological burden in patients, who are frequently reported to have depression and anxiety. The aim of this study was to investigate the association between stress-related hormone levels and psychological stress in vitiligo. Materials and methods: In this study46 vitiligo patients and 46 controls were enrolled; their cortisol, dehydroepiandrosterone sulfate (DHEAS),and cortisol/DHEAS levels were measured. Psychological burden was assessed by the Beck Depression Inventory and Perceived Stress Scale. Results: Patients and controls did not differ in terms of cortisol, DHEAS, or cortisol/DHEAS. Patients had higher perceived stress than controls but did …
The Role Of Ifih1 Gene Rs1990760 And Rs2111485 Single-Nucleotide Polymorphisms In Generalized Vitiligo Predisposition, Duru Onan, Ahu Yorulmaz, Fati̇h Süheyl Ezgü, Kadi̇r Mutlu Hayran, Seray Külcü Çakmak, Refi̇ka Ferda Artüz, Başak Yalçin
The Role Of Ifih1 Gene Rs1990760 And Rs2111485 Single-Nucleotide Polymorphisms In Generalized Vitiligo Predisposition, Duru Onan, Ahu Yorulmaz, Fati̇h Süheyl Ezgü, Kadi̇r Mutlu Hayran, Seray Külcü Çakmak, Refi̇ka Ferda Artüz, Başak Yalçin
Turkish Journal of Medical Sciences
Interferon-induced helicase (IFIH1) is a gene locus that has been recently defined as a candidate for susceptibility to generalized vitiligo (GV). The objectives of this study were to assess the association of IFIH1 gene, rs2111485, and rs1990760 single-nucleotide polymorphisms (SNP) with susceptibility to GV and the autoimmune diseases accompanying GV.Materials and methods: We prospectively studied GV patients and frequency-matched healthy controls by age and sex. The genotypes of the participants were determined for rs1990760 and rs2111485 SNPs of IFIH1. Dominant, recessive, and additive models were evaluated for each SNP adjusted for age and sex. Results: The patients and their controls …