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Full-Text Articles in Medicine and Health Sciences
Does Hand Grip Strength Decrease In Chronic Obstructive Pulmonary Disease Exacerbation? A Cross-Sectional Study, Zeynep Turan, Özden Özyemi̇şci̇ Taşkiran, Zeynep Erden, Nurdan Köktürk, Gülçi̇n Kaymak Karataş
Does Hand Grip Strength Decrease In Chronic Obstructive Pulmonary Disease Exacerbation? A Cross-Sectional Study, Zeynep Turan, Özden Özyemi̇şci̇ Taşkiran, Zeynep Erden, Nurdan Köktürk, Gülçi̇n Kaymak Karataş
Turkish Journal of Medical Sciences
Background/aim: Respiratory and peripheral muscle strength are reduced in chronic obstructive pulmonary disease (COPD). There is a well-known correlation between handgrip strength (HGS) and strenght extremity muscles. Our aim in this study was to measure HGS and investigate the related factors in COPD patients with exacerbation.Materials and methods: Subjects with COPD exacerbation (n = 101) and stable COPD (n = 22), and subjects without COPD (n = 201), were enrolled in this study. Age, sex, and body mass index were similar. HGS was measured using a Vigorimeter. Pulmonary function tests and 6-min walk tests were performed.Results: The mean HGS was …
Diaphragmatic Thickness In Chronic Obstructive Lung Disease And Relationship With Clinical Severity Parameters, Nalan Ogan, Yusuf Aydemi̇r, Togay Evri̇n, Gökçe Kaan Ataç, Ayşe Baha, Burak Kati̇poğlu, Banu Süzen, Evri̇m Eylem Akpinar
Diaphragmatic Thickness In Chronic Obstructive Lung Disease And Relationship With Clinical Severity Parameters, Nalan Ogan, Yusuf Aydemi̇r, Togay Evri̇n, Gökçe Kaan Ataç, Ayşe Baha, Burak Kati̇poğlu, Banu Süzen, Evri̇m Eylem Akpinar
Turkish Journal of Medical Sciences
Background/aim: Sonographic assessment of diaphragm structure and function would be a useful clinical tool in patients with chronic obstructive pulmonary disease (COPD). Our aim was to determine the muscle thickness of the diaphragm and the usefulness of clinical practice in patients with COPD.Materials and methods: The diaphragmatic thickness of 34 COPD patients and 34 healthy subjects was measured during tidal volume (Tmin) and deep inspiration (Tmax) on both sides using a B-mode ultrasound. The body mass index and the modified Medical Research Council (mMRC) index values were reported.Results: There was no correlation among TminR (P = 0.134), TminL (P = …
The Effect Of Hypoxia On Hearing Function, Nevreste Di̇dem Sonbay Yilmaz, Cem Saka, Burcu Arslan, Nurdan Aygener Yeşi̇lyurt, Di̇lek Saka, Sadik Ardiç, İstemi̇han Akin
The Effect Of Hypoxia On Hearing Function, Nevreste Di̇dem Sonbay Yilmaz, Cem Saka, Burcu Arslan, Nurdan Aygener Yeşi̇lyurt, Di̇lek Saka, Sadik Ardiç, İstemi̇han Akin
Turkish Journal of Medical Sciences
Background/aim: This study was conducted to determine the critical partial oxygen pressure (pO2) value that would impair hearing function by evaluating the effects of hypoxia on hearing function in subjects diagnosed with chronic obstructive pulmonary disease (CPOD).Materials and methods: The study included 25 male and 5 female patients referred to our clinic who were diagnosed with COPD, according to spirometry and PaO2 values, and who did not show pathology upon autoscopic examination. The control group consisted of 14 female and 16 male patients who had no lung disease and were in the same age range as the COPD group. Results: …
8-Hydroxy-2'-Deoxyguanosine As A Biomarker Of Oxidative Stress In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease, Xing Liu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng
8-Hydroxy-2'-Deoxyguanosine As A Biomarker Of Oxidative Stress In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease, Xing Liu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng
Turkish Journal of Medical Sciences
8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a biomarker of oxidative stress and has been implicated in many diseases. The aim of this study was to investigate the clinical value of plasma 8-OHdG level in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Materials and methods: A total of 154 subjects were enrolled in this study, including 20 healthy volunteers, 24 COPD patients in the stable phase, and 110 AECOPD patients. Peripheral blood samples, demographic information, and clinical characteristics were collected from all subjects at the time of being recruited into the study. Plasma 8-OHdG level was detected by enzyme-linked immunosorbent assay.Results: 8-OHdG …