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Protocol For A Longitudinal Study To Evaluate The Use Of Tenofovir-Based Prep For Safer Conception And Pregnancy Among Women In South Africa, Lynn T. Matthews, Manjeetha Jaggernath, Yolandie Kriel, Patricia Smith, Kasey O’Neil, David Bangsberg, Multiple Additional Authors
Protocol For A Longitudinal Study To Evaluate The Use Of Tenofovir-Based Prep For Safer Conception And Pregnancy Among Women In South Africa, Lynn T. Matthews, Manjeetha Jaggernath, Yolandie Kriel, Patricia Smith, Kasey O’Neil, David Bangsberg, Multiple Additional Authors
OHSU-PSU School of Public Health Faculty Publications and Presentations
Introduction Women who choose to conceive a baby with a partner living with HIV or a partner whose HIV serostatus is unknown in HIV-endemic settings need prevention strategies to mitigate HIV acquisition during conception and pregnancy.
Methods and analysis We are conducting a single-arm longitudinal study offering oral tenofovirdisoproxil fumarate/emtricitabine (TDF/FTC) as pre-exposure prophylaxis (PrEP) for periconception use to 350 HIV-uninfected women in KwaZulu-Natal, South Africa. PrEP is offered as part of woman-centred safer conception programme that promotes couples-based HIV counselling and testing, antiretroviral therapy for partners who are HIV-infected, treatment for sexually transmitted infections and safer conception strategies, such …