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Full-Text Articles in Medicine and Health Sciences

Knowledge Of Management Of Musculoskeletal Problems: Assessment Of Students Enrolled In Four Professional Programs At The University Of Alabama At Birmingham, Patricia Lee Perez Jan 2011

Knowledge Of Management Of Musculoskeletal Problems: Assessment Of Students Enrolled In Four Professional Programs At The University Of Alabama At Birmingham, Patricia Lee Perez

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Background: Previous studies point to inadequate knowledge of musculoskeletal medicine for both student and practicing physicians and physical therapists. Professions with practice regulations that allow direct access by the consumer to healthcare should be assessed to determine competence in managing musculoskeletal conditions. Objective: The objective of this study was to determine if there is a difference in knowledge of the management of musculoskeletal conditions in students enrolled in four professional programs at the University of Alabama at Birmingham (UAB). Methods: Students enrolled in the last semester of medical school (MD), adult nurse practitioner (NP), physical therapy (PT) and physician assistant …


Vitamin D And Insulin Sensitivity Among African American And European American Adolescents And Adults, Jessica Alejandra Alvarez Jan 2011

Vitamin D And Insulin Sensitivity Among African American And European American Adolescents And Adults, Jessica Alejandra Alvarez

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Adequate vitamin D status is associated with a reduced risk for type 2 diabetes (T2DM); the relationship may be mediated by insulin sensitizing effects of vitamin D. African Americans (AA) are at a greater risk for T2DM and insulin resistance, as well as vitamin D deficiency, compared to European Americans (EA). The primary objective of this dissertation was to investigate the independent relationships of vitamin D with various measures of insulin sensitivity. Investigations were performed in a series of studies involving adolescent and adult female cohorts. The intravenous glucose tolerance test-derived insulin sensitivity index (SI) or the oral glucose tolerance …


Altered Dna Methylation Of Repetitive Elements May Explain The Modified Risk Of Cervical Intraepithelial Neoplasia (Cin) Associated With Genetic Polymorphisms Of The Folate Metabolic Pathway In The Us Post Folic Acid Fortification Era, Suguna Badiga Jan 2011

Altered Dna Methylation Of Repetitive Elements May Explain The Modified Risk Of Cervical Intraepithelial Neoplasia (Cin) Associated With Genetic Polymorphisms Of The Folate Metabolic Pathway In The Us Post Folic Acid Fortification Era, Suguna Badiga

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Despite the controversy regarding the adverse effects of exposure to higher folate concentrations on health outcomes particularly cancer, there has been paucity of research to understand the biological mechanisms affected by such exposures in relation to the risk of developing pre-cancer or cancer. We have recently addressed this concern by demonstrating that higher plasma folate concentrations were not associated with greater risk of being diagnosed with higher grades of cervical intraepithelial neoplasia (CIN 2+) especially in women with sufficient plasma vitamin B12 concentrations. Higher plasma folate was also associated with a pre-cancer protective level of peripheral blood mononuclear cells (PBMC) …


Effects Of Growth Factor Induced Pathways On Differentiation Of The Human Neuronal Cell Line Sh-Sy-5y., Ashish D. Dwary Jan 2011

Effects Of Growth Factor Induced Pathways On Differentiation Of The Human Neuronal Cell Line Sh-Sy-5y., Ashish D. Dwary

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Background: The VSNL1 gene product, Visinin-like-protein-1 (VILIP-1), is a member of the neuronal EF-hand Ca2+-sensor protein family. Previously, VILIP-1 mRNA and protein expression were shown to be altered in animal models and in schizophrenia patients. VILIP-1 influences cytosolic cAMP levels, cell migration, exocytotic processes and differentiation in the periphery. This raises the question, whether similar to other potential schizophrenia susceptibility genes, such as Disc1, PDE4B and Akt, VILIP-1 may be associated with schizophrenia-related measures, and if it could mechanistically affect cAMP signaling and neurite outgrowth in neurons. Methods: 627 people with schizophrenia and 541 control subjects were ascertained and the …


"The Role Of Health Promotion In Physical Therapy Survey" Reliability And Validity Testing", Jaca Stephens Jan 2011

"The Role Of Health Promotion In Physical Therapy Survey" Reliability And Validity Testing", Jaca Stephens

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ABSTRACT Purpose: Physical therapists (PTs) have a unique opportunity to play a meaningful role in educating patients on health and wellness to prevent chronic conditions, such as cardiac disease, cerebrovascular disease, pulmonary disease, cancer, diabetes, and obesity. No instrument has been validated to measure physical therapists' views on health promotion and their practices. The purpose of this study was to evaluate the validity and reliability of a health promotion survey designed for physical therapists. Method: An expert panel of 9 physical therapists assessed the content validity of "The Role of Health Promotion in Physical Therapy Survey." as developed by Rea …


Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton Jan 2011

Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton

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Nuclear receptor NR4A3 (NOR-1, MINOR) mediates transcriptional responses to ß-adrenergic signaling, is increased in insulin sensitive mice and humans, and enhances insulin-stimulated glucose transport in cultured adipocytes and myocytes. We therefore sought to determine the role of NR4A3 in in vivo adipose tissue and skeletal muscle physiology. Following adipose-specific NR4A3 over-expression in mice, we observed reduced circulating epinephrine due to enhanced catabolism of catecholamines in adipose tissue. Furthermore, this reduction in circulating epinephrine produced broad physiological consequences, including poor glucose tolerance, reduced insulin sensitivity, dyslipidemia, poor cardiac function, and behavioral alterations. In skeletal muscle, we show that NR4A3 protein associates …


The Association Between The Body Mass Index (Bmi) Of African American College Women And Their Exposure To Magazine Advertisements, Candice P. Prince Jan 2011

The Association Between The Body Mass Index (Bmi) Of African American College Women And Their Exposure To Magazine Advertisements, Candice P. Prince

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The primary purpose of this study was to examine the association between body mass index (BMI) and exposure to magazine advertisements among African-American college women aged 19 to 29. This study also sought to determine how personal, behavioral, and environmental factors affect the BMI of African-American college women. A sample of 252 African-American college women enrolled in undergraduate degree programs in the Southeast United States completed a web-based survey on their weight-related health behaviors and magazine usage. Descriptive statistics, bivariate correlations, and multivariable regression analysis were used to analyze the data. Bivariate correlations showed significant associations between BMI and several …


Organizational Configurations And Strategies Related To Financial Performance In Medical Group Practices: A Test Of Porter's Generic Strategies, Todd Brenton Smith Jan 2011

Organizational Configurations And Strategies Related To Financial Performance In Medical Group Practices: A Test Of Porter's Generic Strategies, Todd Brenton Smith

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Research in the field of organizational configurations (OC) involves the formation of groups of firms that are similar to each other on certain characteristics, and dissimilar from other groups, and explores organizational performance differences between the groups (Ketchen & Shook, 1996; Short, Payne, and Ketchen, 2008). However, OC is replete with literature lacking in common key terms, measurement methods, and specification of variables, and too few empirical articles with a strong theoretical basis have been published (Short, Payne, & Ketchen, 2008). Porter's (1980, 1985) generic strategies are a specific typology within the field of OC that have been used extensively …


Calciotropic Hormonal Influence On Energy Homeostasis, Lynae J. Hanks Jan 2011

Calciotropic Hormonal Influence On Energy Homeostasis, Lynae J. Hanks

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Energy balance exists when intake is equivalent to expenditure. It has become evident that beyond quantitative aspects of intake, dietary components also have directive impact. On the expenditure side, an underappreciated yet key contributor is resting energy expenditure (REE). As the largest constituent of overall energy output, REE encompasses physiologic, dietary and genetic influence on body composition. While cellular and overall systemic contribution cannot be ignored, the relative proportion of adipose, bone and lean body tissue (i.e., body composition) represents the primary determinant underlying REE. It is possible that the mineral calcium is a common denominator encompassing energy balance influenced …


Comparison Of Vitamin D Supplementation Regimens In Pediatric Patients With Cystic Fibrosis, Julianna Bailey Jan 2011

Comparison Of Vitamin D Supplementation Regimens In Pediatric Patients With Cystic Fibrosis, Julianna Bailey

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COMPARISON OF VITAMIN D SUPPLEMENTATION REGIMENS IN PEDIATRIC PATIENTS WITH CYSTIC FIBROSIS JULIANNA BAILEY CLINICAL NUTRITION ABSTRACT The objective of this randomized prospective study was to determine the most efficacious form of vitamin D supplementation for pediatric patients with Cystic Fibrosis (CF). We hypothesized that 50,000 IU monthly cholecalciferol would be as effective in raising serum 25-hyrdroxyvitamin D [25(OH)D] concentrations as routine daily supplementation of 1000-2000 IU cholecalciferol in pediatric patients with CF, birth to 20 years of age, over a period of 3 months. Data collected at baseline included serum 25(OH)D concentration, gender, genotype, race, age, FEV1, height, weight, …