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Effects Of Endurance Training On Skeletal Muscle Mass And Inflammation In A Rat Model Of Heart Failure, Aaron Garcia, Dillon Harris, Quinten Pigg, Daniela Sayuri Inoue, Mariana Janini Gomes

International Journal of Exercise Science: Conference Proceedings

Chronic disease states including heart failure (HF) often lead to reduced physical activity, resulting in disuse and low-level systemic inflammation, which contribute to the decline in muscle mass and function. An important goal of therapy in HF patients is to counteract or prevent the development of skeletal muscle alterations in order to restore a normal functional capacity. Exercise is an established means of improving exercise capacity and quality of life in patients with HF. Therefore, we aimed to evaluate the impact of an endurance program on skeletal muscle mass and inflammation in a rat model of pulmonary arterial hypertension (PAH)-induced …