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Medicine and Health Sciences Commons

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Maternal and Child Health

Aga Khan University

Institute for Human Development

Neurodevelopment

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Full-Text Articles in Medicine and Health Sciences

Emotional And Behavioural Outcomes In Childhood For Survivors Of Group B Streptococcus Invasive Disease In Infancy: Findings From Five Low And Middle-Income Countries, Jaya Chandna, Wan-Hsin Liu, Ziyaad Dangor, Shannon Leahy, Santhanam Sridhar, Hima B. John, Humberto Mucasse, Quique Bassat, Azucena Bardaji, Amina Abubakar Jan 2022

Emotional And Behavioural Outcomes In Childhood For Survivors Of Group B Streptococcus Invasive Disease In Infancy: Findings From Five Low And Middle-Income Countries, Jaya Chandna, Wan-Hsin Liu, Ziyaad Dangor, Shannon Leahy, Santhanam Sridhar, Hima B. John, Humberto Mucasse, Quique Bassat, Azucena Bardaji, Amina Abubakar

Institute for Human Development

Background: Survivors of invasive Group B streptococcus (iGBS) disease, notably meningitis, are at increased risk of neurodevelopment impairment (NDI). However, the limited studies to date have a median follow-up to 18 months and mainly focused on moderate/severe NDI, with no previous studies on emotional-behavioural problems among iGBS survivors.

Methods: In this multi-country, matched cohort study, we included children aged 18 months to 17 years with infant iGBS sepsis and meningitis from health demographic surveillance systems, or hospital records in Argentina, India, Kenya, Mozambique and South Africa. Children without iGBS history were matched to iGBS survivors on sex and …