Medicine and Health Sciences Commons^™

Development Of A Food Composition Database For The Estimation Of Dietary S-Methyl Cysteine Sulfoxide From Vegetables, Caroline R. Hill, Emma L. Connolly, Armaghan Shafaei, Lois Balmer, Liezhou Zhong, Taulant Muka, Antonietta Hayhoe, Shikha Saha, Richard J. Woodman, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

A food composition database estimating S-methyl cysteine sulfoxide (SMCSO) was created following a systematic literature search. SMCSO data (705 entries) from 19 vegetables were summarised: brassicas (n = 10) and alliums (n = 9). The highest SMCSO in brassicas was reported in Brussels sprouts (median [range]: 318 [68−420] mg/100 g fresh weight (FW)) whilst the lowest was in radish (19 [4–45] mg/100 g FW). Brussels sprouts were almost twice as concentrated in SMCSO as cauliflower, followed by cabbage, kale, broccoli, kohlrabi, swede, Chinese cabbage, and turnips. The alliums highest in SMCSO were Chinese chives (271 [185−413] mg/100 g FW) followed …

Positron Emission Tomography In Oncology And Environmental Science, Samantha Delaney

Dissertations, Theses, and Capstone Projects

The last half century has played witness to the onset of molecular imaging for the clinical assessment of physiological targets. While several medical imaging modalities allow for the visualization of the functional and anatomical properties of humans and living systems, few offer accurate quantitation and the ability to detect biochemical processes with low-administered drug mass doses. This limits how physicians and scientists may diagnose and treat medical issues, such as cancer, disease, and foreign agents.

A promising alternative to extant invasive procedures and suboptimal imaging modalities to assess the nature of a biological environment is the use of positron emission …

Flanker Task Performance In Young And Older Adults: A Behavioral And Erp Study, Fatima Medrano

Dissertations, Theses, and Capstone Projects

Research suggests that as we get older, executive function abilities decline (Hasher & Zacks, 1988; Salthouse, 1996). One affected ability is that of inhibitory control, which aids in monitoring our responses to non-target stimuli or information. Current research on inhibition reveals inconsistencies across studies. Monitoring brain responses during the Flanker (used to measure inhibitory control) task may add valuable insight into the processes underlying group differences behaviorally, by studying the N200 and P300 event-related potentials which have been associated with inhibitory control processes. This study investigated whether there are differences between older and younger adults in inhibitory control and whether …

Naturify 2300, Yarina Yiwei Dai

Masters Theses

In my art practice, I explore the interplay between human desires to manipulate and anthropomorphize nature, as seen in the technological augmentation of plants and living entities. This investigation delves into how this intersection, alongside empathy towards these creations, contributes to fears of uncontrollability and the risks of addiction and excessive dependence on technology.

Bioengineering and genetic modification have cultivated unprecedented developments, allowing humans to manipulate the fundamental building blocks of life. My research speculates on this technology further, modifying the genetic code of organisms and creating bioengineered wearable entities with enhanced traits or entirely new functionalities. The primary objective …

Environmental Magnesium Ion Affects Global Gene Expression, Motility, Biofilm Formation And Virulence Of Vibrio Parahaemolyticus, Xue Li, Xiaobai Zhang, Miaomiao Zhang, Xi Luo, Tingting Zhang, Xianjin Liu, Renfei Lu, Yiquan Zhang

Journal Articles

No abstract provided.

Innovation In Bioinformatics: Recent Tools, Database And Involvement Of Artificial Intelligence, Aziz Ahmed, Mohd Shuaib, Abdulbasid Banga, Rizwan Ahmad

Indonesian Journal of Medical Chemistry and Bioinformatics

Bioinformatics has evolved in recent years into a crucial subject and a well-liked research area that is interconnected with many approaches and disciplines. The capacity of bioinformatics and its approaches to tackle challenging biological problems and promote research and development. There are various tools and database which are used in bioinformatics. AI is the capacity of a computational system to carry out various activities associated with intellectual beings and as a computer system's imitation of human intelligence processes. The bioinformatics applications with artificial intelligence have the capacity to annotate the data in the direction of logical conclusions. By combining AI …

Nature Of The Evidence Base And Approaches To Guide Nutrition Interventions For Individuals: A Position Paper From The Academy Of Nutrition Sciences, Mary Hickson, Constantina Papoutsakis, Angela M Madden, Mary Anne Smith, Kevin Whelan

Journal Articles

This Position Paper from the Academy of Nutrition Sciences is the third in a series which describe the nature of the scientific evidence and frameworks that underpin nutrition recommendations for health. This paper focuses on evidence which guides the application of dietary recommendations for individuals. In some situations, modified nutrient intake becomes essential to prevent deficiency, optimise development and health, or manage symptoms and disease progression. Disease and its treatment can also affect taste, appetite and ability to access and prepare foods, with associated financial impacts. Therefore, the practice of nutrition and dietetics must integrate and apply the sciences of …

Smear Layer Removal Using Two Different Ni-Ti Instruments With Two Different Irrigating Systems. An Invitro Study, Tasneem Mohamed Reyad, Wael Ahmed Hessein, Ahmed Abdelrahman Hashem Ah, Said Abd Elhafiz

Future Dental Journal

Objectives: To evaluate and compare smear layer removal in root canals instrumented with two single Ni-Ti rotary instruments with two different irrigating systems. Materials and Methods: Sixty recently extracted single-rooted mandibular premolars teeth were decoronated to a standardized length of 14 mm. Roots were divided into two main groups (n=30) according to the rotary NiTi file used for instrumentation either with One Shape (OS) file or with One Curve file (OC). Each main group was subdivided into three subgroups according to the methods used to agitate the irrigating solutions either sonically or ultrasonically as following: Group A was subdivided into …

Caffeine’S Impact On Heart Rate Variability During Short-Term Exercise In University Students, Maya J. Spinler, Morgan M. Payne, Christopher Carroll Dr.

Human Kinetics & Applied Health Sciences Student Works

The primary objective is to explore the physiological effects of caffeine on intra-bout exercise-induced blood pressure (BP) and heart rate (HR) deceleration resulting from repeated anaerobic exercise cycling in active university students. Use of caffeinated stimulants has increased in recent years, particularly in the exercise setting. The cardiovascular system (CS) is an essential piece of exercise physiology and is controlled by the autonomic nervous system (ANS). Caffeine has a known effect on the CS during acute exercise. What is not well solidified is the connection between caffeine and exercise-induced markers, such as heart rate recovery (HRR) and BP. Participants underwent …

Ankle Mobility And Balance In A Healthy College-Aged Population: A Correlational Study, Anna G. Johnson, Madelyn M. Roiger, Elisa M. Stewart

Human Kinetics & Applied Health Sciences Student Works

A review of current literature shows a relationship between ankle mobility and balance in an older population, with limited evidence in younger, healthy populations. To bridge this gap, this study aims to explore this relationship in a healthy, college-aged population. Maintaining upright balance is an integrated effort by the vestibular, somatosensory, and visual systems. Regaining a loss of balance happens with three strategies: an ankle strategy for small perturbations, a hip strategy for moderate perturbations, and a stepping strategy for the largest loss to regain a new base of support. Taking these sequential responses into account, the investigators specifically looked …

Proteomic Characterization And Cytotoxic Potential Of Proteins From Cuscuta (Cuscuta Epithymum (L.) Crude Herbal Product Against Mcf-7 Human Breast Cancer Cell Line, Umaima Akhtar, Yamna Khurshid, Bishoy El-Aarag, Basir Syed, Ishtiaq A. Khan, Keykavous Parang, Aftab Ahmed

Pharmacy Faculty Articles and Research

Background

The burden of breast cancer, the second leading cause of death worldwide, is increasing at an alarming rate. Cuscuta, used in traditional medicine for different ailments, including cancer, is known for containing phytochemicals that exhibit anticancer activity; however, the bioactivities of proteins from this plant remain unexplored. This study aimed to screen the cytotoxic potential of proteins from the crude herbal product of Cuscuta epithymum(L.) (CE) harvested from the host plants Alhagi maurorum and Medicago sativa.

Methods

The proteins from CE were extracted using a salting-out method, followed by fractionation with a gel filtration chromatography column. Gel-free shotgun …

A Potential Of Watercress Nasturtium Officinale Bioactive Compounds In Inhibiting Infectious Myonecrosis Virus (Imnv) By Targeting Rna-Dependent Rna Polymerase (Rdrp) Virus From Several Countries: In Silico Approach, Qurrota A’Yunin, Fatchiyah Fatchiyah, Maftuch Maftuch, Feri Eko Hermanto, Muhammad Hermawan Widyananda, Narendra Santika Hartana, Muhaimin Rifa’I, Yoga Dwi Jatmiko

Karbala International Journal of Modern Science

Infectious myonecrosis virus (IMNV) disease causes mass mortality and decreased shrimp production. The RdRp region projects to the interior, where it may function in transcription. The focus of this study was to determine the effect of amino acid polymorphisms from several countries on the structure of RdRp and identify the potential of watercress in inhibiting IMNV by targeting the RdRp protein of IMNV through an in silico approach. The results showed that the structure of the IMNV RdRp protein from Indonesia was similar to Mexico, and the protein structure from India_QDN was identical to India_QIL. Ligand binding affinity values showed …

Lyme Disease In The Northeast: The Unintended Consequence Of Suburban Development, Hayden Neubert

Student Theses 2015-Present

This paper addresses the role of suburban development in the suburbs of the Northeastern United States in increasing human Lyme disease infection. Over the past 50 years, Lyme disease has become the most common vector-borne disease in the United States. In 2021, the two states with the most Lyme disease cases were New York and New Jersey, with a collective 6,524 cases, with Connecticut still representing 541 total cases. It is not a coincidence that case numbers are concentrated in suburban areas with high forest fragmentation. Chapter 1 of this essay analyzes how human land development disrupts bioregulatory ecosystem actors …

Exploring The Design Space Of Antifungal Peptides, Miryam Kikhwa

Seton Hall University Dissertations and Theses (ETDs)

The synthesis, characterization, and evaluation of antifungal activity of peptides FQ15 and FG10 will be conducted to address the hypothesis. The hypothesis of this thesis is that a peptide with similar properties to AS15 would have similar activity against Cryptococcus neoformans. This study addresses the challenge of drug- resistant microbes by developing inhibitors targeting lipid flippase and exploring their potential as antimicrobial agents against Cryptococcus neoformans. Chapter 1 provides a historical context of the background on the development of antimicrobials and common antifungal treatments, as well as an introduction about C. neoformans and its resistance mechanism. Chapter 2 introduces the …

Impact Of Temperature On Children’S Nutrition: A Comparative Study Of Three Ecological Regions Of Nepal, Prakriti Shakya

Master's Theses

Nutrition obtained during the growth period of childhood significantly influences long-term well-being and overall productivity, ultimately contributing to the economy of a society. However, weather shocks can wreak havoc by damaging crops, changing yields of important crops and disrupting market access, which directly impacts the food intake of both adults and children. When these adverse events occur during childhood, short term and long term inadequacy in nutrition as well as disease incidence can cause malnutrition leading to stunted growth and cognitive impairment that may persist into adulthood, affecting the labor market and increasing health expenditure. To address this issue, we …

Towards A New Role Of Mitochondrial Hydrogen Peroxide In Synaptic Function, Cliyahnelle Z. Alexander

Student Theses and Dissertations

Aerobic metabolism is known to generate damaging ROS, particularly hydrogen peroxide. Reactive oxygen species (ROS) are highly reactive molecules containing oxygen that have the potential to cause damage to cells and tissues in the body. ROS are highly reactive atoms or molecules that rapidly interact with other molecules within a cell. Intracellular accumulation can result in oxidative damage, dysfunction, and cell death. Due to the limitations of H₂O₂ (hydrogen peroxide) detectors, other impacts of ROS exposure may have been missed. HyPer7, a genetically encoded sensor, measures hydrogen peroxide emissions precisely and sensitively, even at sublethal levels, during …

A Mathematical Modeling Study On Hdv Rna, Alt, And Hbsag Dynamics Reveals Dual Mechanisms Of Peginterferon-Lambda., Adquate Mhlanga, Ohad Etzion, Harel Dahari

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling Of Intracellular Compartmentalized Gpcr Signaling, Léo Darrigade

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Model Of Oocyte Population Dynamics For Fish Oogenesis, Louis Fostier, Frédérique Clément, Romain Yvinec, Violette Thermes

Biology and Medicine Through Mathematics Conference

No abstract provided.

Time-Dependent Antibody Kinetics For Infected And Vaccinated Individuals Via Graph-Theoretic Modeling, Rayanne Luke, Prajakta P. Bedekar, Anthony Kearsley

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Histological Data-Driven Analysis Of The Hypoxic Microenvironment Of Preclinical Murine Bladder Tumors, Awino Maureiq E. Ojwang'

Biology and Medicine Through Mathematics Conference

No abstract provided.

Astrocyte Spatial Distribution Affects Growth Dynamics Of Breast Cancer Brain Metastases: An Agent-Based Modeling Study, Rupleen Kaur

Biology and Medicine Through Mathematics Conference

No abstract provided.

Reaction-Diffusions System Simulated On Irregular Shapes And Surfaces Model Petal Spot Patterns In Monkeyflower Hybrids, Emily Simmons, Arielle M. Cooley, Joshua R. Puzey, Gregory D. Conradi Smith

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling And Control Of Drug Resistance In Cancer Dynamics, James Greene

Biology and Medicine Through Mathematics Conference

No abstract provided.

On The Effect Of Liquid Crystal Orientation In The Lipid Layer On Tear Film Thinning And Breakup, Mary Taranchuk

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Model Of Shell Structure And Pattern In Mollusks, Rahnuma Islam, Bard Ermentrout, Sabrina Streipert

Biology and Medicine Through Mathematics Conference

No abstract provided.

Exploring The Evolution Of Altruistic Punishment Using A Pde Model For Multilevel Selection, Daniel Cooney

Biology and Medicine Through Mathematics Conference

No abstract provided.

Using Splines To Investigate The Effects Of Temperature On The Within-Mosquito Malaria Parasite Forms, Alexander J. Diefes, Miranda I. Teboh-Ewungkem

Biology and Medicine Through Mathematics Conference

No abstract provided.

Identifiability Analysis And Model Reduction For Soft Tissue Models, Mansoor A. Haider

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling Mechanisms Of Microtubule Dynamics And Polarity In Neurons, Anna Nelson, Veronica Ciocanel, Scott Mckinley, Hannah Scanlon

Biology and Medicine Through Mathematics Conference

No abstract provided.