Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Effects Of Alpha Lipoic Acid And Vitamin C Supplementation On Transforming Growth Factor Alpha (Tgf \Alpha) And Transforming Growth Factor Beta 2 (Tgf \Beta2)Secretion In Testicular Tissue Of Diabetic Rats, Sevda Eli̇ş Yildiz, Buket Bakir, Hami̇t Uslu, Ebru Karadağ Sari, Musa Karaman
Effects Of Alpha Lipoic Acid And Vitamin C Supplementation On Transforming Growth Factor Alpha (Tgf \Alpha) And Transforming Growth Factor Beta 2 (Tgf \Beta2)Secretion In Testicular Tissue Of Diabetic Rats, Sevda Eli̇ş Yildiz, Buket Bakir, Hami̇t Uslu, Ebru Karadağ Sari, Musa Karaman
Turkish Journal of Veterinary & Animal Sciences
The effects of alpha lipoic acid and vitamin C supplementation on TGF \alpha and TGF \beta2 secretion in the testicular tissue of streptozotocin-induced diabetic rats were examined by immunohistochemical methods. Rats were divided into 5 groups; group 1 (control), 2 (diabetic control), 3 (diabetes + alpha lipoic acid), 4 (diabetes + vitamin C), and 5 (diabetes + alpha lipoic acid + vitamin C). Hematoxylin and eosin staining was performed in order to examine testicular tissue histopathologically. The streptavidin-biotin-peroxidase complex method was used for histological examination and determination of TGF \alpha and TGF \beta2 localization in the testicular tissue. Regarding fasting …
Comparison Of Some Kinetic Properties Of Pyruvate Kinase In Liver Tissue Of Normal And Diabetic Rats, Seval Yilmaz
Comparison Of Some Kinetic Properties Of Pyruvate Kinase In Liver Tissue Of Normal And Diabetic Rats, Seval Yilmaz
Turkish Journal of Veterinary & Animal Sciences
Diabetes mellitus was induced in Wistar-Albino type male rats with a single dose of streptozotocin (60 mg/kg intraperitoneally). The kinetic properties of pyruvate kinase were investigated in normal and diabetic rat liver tissue. In normal rat liver tissue, the incubation period of pyruvate kinase was 15 min and the optimum pH was 8. In diabetic rat liver tissue, the incubation period of pyruvate kinase was 10 min and the optimum pH was 7. Activation was found in normal and diabetic rat liver tissues with magnesium chloride and potassium chloride. Phospho(enol)pyruvate is an enzyme substrate; in the absence of the fructose-1,6-diphosphate …