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Full-Text Articles in Medicine and Health Sciences

The Role Of Serum Histones In Canine Heat Stroke, Jenna Acutt Jan 2019

The Role Of Serum Histones In Canine Heat Stroke, Jenna Acutt

Scripps Senior Theses

Rising temperatures all over the world has correlated with more frequent heat stroke related injuries and death. This statistic not only applies to humans, but to canines as well, who have similar body temperature thresholds. Recent studies have demonstrated that serum histones, released after cell death from heat stroke, play a role in heat stroke related injuries and death. This proposal aims to determine the severity of the effects caused by serum histone release after heat stroke by exposing selected canine cell lines to cell lysate and purified histones H2A, H2B, H3, and H4, which have been found to be …


Two Cases Of Phacoemulsification In The Presence Of A Small Pupil Using An Iris Expander, Ha-Eun Lee, Joon-Young Kim, Da-Eun Lee, Jin-Gu Kang Jan 2019

Two Cases Of Phacoemulsification In The Presence Of A Small Pupil Using An Iris Expander, Ha-Eun Lee, Joon-Young Kim, Da-Eun Lee, Jin-Gu Kang

Turkish Journal of Veterinary & Animal Sciences

A small pupil and poor pupil dilation are well-known risk factors faced by veterinary ophthalmologists during and after cataract surgery. We here describe two cases of phacoemulsification performed using an iris expander (Visitec I-Ring Pupil Expander, Beaver-Visitec International, USA) for treating cataracts in dogs with small pupils. Using this technique, we performed cataract extraction effectively in dogs with insufficiently dilated pupils. This case report provides useful information on the use of an iris expander for phacoemulsification in eyes with a small pupil, which can be applied in veterinary settings.


Proliferation Effects Of Phenylboronic Acid And Boric Acid On Canine Peripheral Blood Mononuclear Cells, Uçkun Sai̇t Uçan, Zafer Sayin Jan 2019

Proliferation Effects Of Phenylboronic Acid And Boric Acid On Canine Peripheral Blood Mononuclear Cells, Uçkun Sai̇t Uçan, Zafer Sayin

Turkish Journal of Veterinary & Animal Sciences

The effects of phenylboronic acid (PBA) and boric acid (BA) on the proliferation of canine peripheral blood mononuclear cells (PBMCs) were investigated. Treatment of PBMCs from mixed breed dogs with PBA or BA (0.05 µg/mL) alone elicited blastogenic responses of 0.478 ± 0.438 and 0.499 ± 0.366, respectively. We observed an additive effect on proliferation when purebred Kangal PBMCs were cultured in a combination of BA (0.001 µg/mL) and the mitogenic lectin concanavalin A (1 µg/mL). However, the effects were not statistically significant. We detected varied IL-2 and IL-4 secretion in response to stimulation with boron-containing compounds. Our findings suggest …