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Heterophil Chemotaxis In Chickens With Natural Staphylococcal Infections, James R. Andreasen Jr., Claire B. Andreasen, Mohammad Anwer, Anita E. Sonn
Heterophil Chemotaxis In Chickens With Natural Staphylococcal Infections, James R. Andreasen Jr., Claire B. Andreasen, Mohammad Anwer, Anita E. Sonn
Claire B. Andreasen
Heterophil chemotaxis using heterophils isolated from the peripheral blood of five commercial broiler chickens naturally infected with staphylococcal bacteria was compared by the modified Boyden-chamber technique with chemotaxis of heterophils from two chickens from the same flock not infected with Staphylococcus (field controls) and from four healthy laboratory control broiler chickens. The infected chickens had gross and histologic lesions of staphylococcal tenosynovitis and osteomyelitis. Staphylococci were isolated from the lesions. Hematologic parameters and histologic lesions of infected chickens also were examined. Compared with field and laboratory controls, Staphylococcus-infected chickens had heterophilic leukocytosis. The heterophils of Staphylococcus-infected chickens had significantly lower …
Chicken Heterophil Chemotaxis Using Staphylococcus-Generated Chemoattractants, James R. Andreasen Jr., Claire B. Andreasen, Mohammad Anwer, Anita E. Sonn
Chicken Heterophil Chemotaxis Using Staphylococcus-Generated Chemoattractants, James R. Andreasen Jr., Claire B. Andreasen, Mohammad Anwer, Anita E. Sonn
Claire B. Andreasen
Heterophil chemotaxis, in response to chemotactic factors generated by three different strains of staphylococcal bacteria, was measured using the modified Boyden-chamber technique. Heterophils were obtained from healthy 6-to-8-week-old broiler chickens. Each bacterial strain generated factors that were chemotactic for chicken heterophils. Factors generated by two pathogenic isolates of Staphylococcus aureus, however, induced significantly greater chemotaxis in chicken heterophils than those generated by a nonpathogenic Staphylococcus isolate.