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Full-Text Articles in Medicine and Health Sciences
Bayer Ag V. Housey Pharmaceuticals: Protection For Biotechnological Research Tools Under Section 271(G) Found Wanting, Matthew Barthalow
Bayer Ag V. Housey Pharmaceuticals: Protection For Biotechnological Research Tools Under Section 271(G) Found Wanting, Matthew Barthalow
The University of New Hampshire Law Review
[Excerpt] "Research tools, a subset of biotechnological inventions protected by process patents, are “tools that scientists use in the laboratory, including cell lines, monoclonal antibodies, reagents, animal models, growth factors, combinatorial chemistry and DNA libraries, clones and cloning tools (such as PCR), methods, laboratory equipment and machines.” Many companies base their business models on the ability to find pharmaceutical products using their proprietary drug discovery research tools. Research tools used for drug discovery ‘include bioinformatic methods for identifying the interaction of certain proteins and their association with disease, methods for confirming protein targets, screening assays to identify molecules active against …
Isolation Of Arcanobacterium (Actinomyces) Pyogenes From Abscessed Cattle Kidney And Identification By Pcr, Hasan Basri̇ Ertaş, Ayşe Kiliç, Gökben Özbey, Adi̇le Muz
Isolation Of Arcanobacterium (Actinomyces) Pyogenes From Abscessed Cattle Kidney And Identification By Pcr, Hasan Basri̇ Ertaş, Ayşe Kiliç, Gökben Özbey, Adi̇le Muz
Turkish Journal of Veterinary & Animal Sciences
In this study, the presence of Arcanobacterium spp., which causes a variety of purulent infections involving the skin, joints and visceral organs, was investigated in abscessed kidney samples of cattle. A total of 500 cattle were examined at postmortem and 100 samples with abscess were collected. Arcanobacterium pyogenes was isolated in 40 (40%) of the samples examined. DNA extracted from the isolates were amplified by Polymerase Chain Reaction (PCR) using specific primers derived from plo gene of A. pyogenes and all the isolates were determined to be positive by PCR. It was concluded that PCR employed in this study may …
Isolation Of Clostridium Perfringens From Chickens And Detection Of The Alpha Toxin Gene By Polymerase Chain Reaction (Pcr), Hakan Kalender, Hasan Basri̇ Ertaş
Isolation Of Clostridium Perfringens From Chickens And Detection Of The Alpha Toxin Gene By Polymerase Chain Reaction (Pcr), Hakan Kalender, Hasan Basri̇ Ertaş
Turkish Journal of Veterinary & Animal Sciences
This study was carried out to isolate Clostridium perfringens from chickens and to detect the gene encoding the alpha toxin produced by all types of C. perfringens by polymerase chain reaction (PCR). Intestinal contents of 160 slaughtered chickens from 8 different farms in Elazığ province were analyzed. C. perfringens was isolated from 8 (5%) of the samples. DNA samples extracted from suspected isolates grown on selective agar were amplified by PCR using a pair of primers derived from the alpha toxin gene. All of 8 suspected isolates were found to be C. perfringens by conventional methods and PCR. Isolates were …