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Molecular Characterization Of Fecundity-Related Gene Regions In Some Of Türkiye’S Native Sheep Breeds, Ramazan Aymaz, Fulya Özdi̇l, Yalçın Yaman
Molecular Characterization Of Fecundity-Related Gene Regions In Some Of Türkiye’S Native Sheep Breeds, Ramazan Aymaz, Fulya Özdi̇l, Yalçın Yaman
Turkish Journal of Veterinary & Animal Sciences
In this study, the BMP15 and GDF9 gene regions were examined through DNA sequencing in some native sheep breeds of Türkiye (Kıvırcık, Karacabey Merino, Chios, Gökçeada, Çine Çaparı, Awassi, and Karakacan). In the BMP15 exon 2 region, two single nucleotide polymorphisms (SNPs) were identified: one synonymous SNP, P248P (proline/proline), and one nonsynonymous SNP, L251P (leucine/proline), resulting in a missense mutation. In the GDF9 exon 1 region, only a nonsynonymous SNP, R87H (histidine/ arginine), was found. In the GDF9 exon 2 region, four SNPs were identified: two nonsynonymous SNPs, E241K (glutamate/lysine) and V332I (valine/isoleucine), and two synonymous SNPs, L159L (leucine/leucine) and …