Medicine and Health Sciences Commons^™

Reducing Skin Injury And Breakdown In Neonatal Patients, Emily Herring

Symposium of Student Scholars

Abstract

The integumentary system is known for being the body’s largest organ, comprised of water, fats, protein, and minerals, for which composition plays a significant role in protecting the body against thermal, chemical, and microbial agents. However, the skin’s functionality is reduced in neonates as the stratum corneum is thin at birth due to diminished water-holding capacity (Oranges et al., 2015). The skin’s fragility is further stressed among preterm neonates and newborns in neonatal intensive-care units (NICU) due to medical status, procedures, and exposure to skin irritants (Visscher et al., 2009). Reduction in skin injury and breakdown in NICU patients …

Alternative Precautionary Measures Yielding Lower C. Diff Infection Rates In Healthcare Facilities, Matthew Kramer

Symposium of Student Scholars

Background: An international healthcare concern is the persistent spread of Clostridium difficile, a Gram-positive spore forming bacterium that is responsible for the most common hospital-acquired infection, amongst patients.

Objective: A systematic review was performed to summarize evidence that the interventions utilized in healthcare facilities which indicate a patient’s precautionary status are insufficient, outdated, and commonly lead to infection in neighboring patient rooms. Databases such as PubMed, NCBI, Google Scholar, and APHA’s Medical Care were searched, covering the period from 2017-2022. Studies were included if their focus concentrated on C. diff and the precautionary measures taken by employees at healthcare …

Designing And Synthesizing A Warhead-Fragment Inhibitory Ligand For Ivyp1 Through Fragment-Based Drug Discovery, Samuel Moore

Symposium of Student Scholars

Fragment-based drug discovery (FBDD) is a powerful tool for developing anticancer and antimicrobial agents. Within this, magnetic resonance spectroscopy (NMR) provides a comprehensive qualitative and quantitative approach to screening and validating weak and robust binders with targeted proteins, making NMR among the most attractive strategies in FBDD. Inhibitor of vertebrate lysozyme (Ivyp1) of P. aeruginosa serves as an excellent target because of its active cellular location and implications in clinical prognosis for cystic fibrosis and immunocompromised patients. This study uses current NMR and biophysical techniques to develop a covalent, fragment-linked warhead inhibitor for Ivyp1 through synthetic methods, warhead linking, and …

Analyzing The Past Five Years Of Equinox Week* Programs Focused On Sustainable Development Goals Within A Collection Of Local And Global Initiatives To Support A Proposal For The Publication Of A Comprehensive Book, Abdoulaye Idrissa

Symposium of Student Scholars

Many undergraduate students are not familiar with the research process involved in a book publication proposal. Through this multidisciplinary collaborative research, the faculty intends to minimize this gap by engaging the students in such a process from the early phase of proposal preparation. The student will research and review the past five years of EQUINOX Week* programs focused on Sustainable Development Goals within a collection of local and global initiatives to support a proposal for the EQUINOX proceeding publication.

With an extensive set of qualitative and quantitative data gathered over a span of 5 years. The student will be …