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Endoscopic Evaluation Of The Response To Intrauterine Irrigation With 3.3% N-Acetylcysteine In Mares, Christine T. Kissinger

Honors College

Strangles is a contagious disease caused by the bacteria Streptococcus equi that has continued to affect horses through the development of long-term asymptomatic carriers. Effective identification of horses carrying S. equi and treatment of these horses has proven difficult. The chemical N-acetylcysteine (NAC) has mucolytic properties and has been used in the treatment of carriers; however the reports show controversial and anecdotal evidence regarding the effectiveness and inflammatory side effects. The goal of this study is to observe whether NAC is irritating to mucosal tissue with the interest of determining if NAC could be used to treat the carrier state …