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Articles 1 - 7 of 7
Full-Text Articles in Medicine and Health Sciences
Psychiatric Outcomes In A Resident-Run Multidisciplinary Hepatitis C Clinic, Nicole M. Agostino Do, Edward Norris Md, Fapm, Joseph L. Yozviak Do, Facp, Charles M. Brooks Md, Eric J. Gertner Md, Mph, Michael Kaufmann Md
Psychiatric Outcomes In A Resident-Run Multidisciplinary Hepatitis C Clinic, Nicole M. Agostino Do, Edward Norris Md, Fapm, Joseph L. Yozviak Do, Facp, Charles M. Brooks Md, Eric J. Gertner Md, Mph, Michael Kaufmann Md
Edward R Norris MD, FAPA, FAPM
No abstract provided.
Training Tomorrow’S Providers And Expanding Access To Peginterferon/Ribavirin Combination Therapyfor Chronic Hepatatis C In Underinsured/Uninsured Patients: Final Outcomes Of A Pilot, Resident-Initiated, Multidisciplinary, Hepatitis C Clinic, Nicole M. Agostino Do, Suzanne J. Templer Do, Edward Norris Md, Fapm, Charles M. Brooks Md, Eric J. Gertner Md, Mph, Joseph L. Yozviak Do, Facp
Training Tomorrow’S Providers And Expanding Access To Peginterferon/Ribavirin Combination Therapyfor Chronic Hepatatis C In Underinsured/Uninsured Patients: Final Outcomes Of A Pilot, Resident-Initiated, Multidisciplinary, Hepatitis C Clinic, Nicole M. Agostino Do, Suzanne J. Templer Do, Edward Norris Md, Fapm, Charles M. Brooks Md, Eric J. Gertner Md, Mph, Joseph L. Yozviak Do, Facp
Edward R Norris MD, FAPA, FAPM
No abstract provided.
Effectiveness And Tolerability Of Nevirapine, Stavudine, And Lamivudine In Clinical Practice, Joseph Yozviak, R Doerfler, William Woodward
Effectiveness And Tolerability Of Nevirapine, Stavudine, And Lamivudine In Clinical Practice, Joseph Yozviak, R Doerfler, William Woodward
Joseph L Yozviak DO, FACP
No abstract provided.
Resuppression Of Virus Load After Interruption In Treatment With Nevirapine And 2 Nucleoside Reverse-Transcriptase Inhibitors, Joseph Yozviak, R Doerfler, William Woodward
Resuppression Of Virus Load After Interruption In Treatment With Nevirapine And 2 Nucleoside Reverse-Transcriptase Inhibitors, Joseph Yozviak, R Doerfler, William Woodward
Joseph L Yozviak DO, FACP
No abstract provided.
Structural And Thermodynamic Basis Of Amprenavir/Darunavir And Atazanavir Resistance In Hiv-1 Protease With Mutations At Residue 50, Seema Mittal, Rajintha Bandaranayake, Nancy King, Moses Prabu-Jeyabalan, Madhavi Nalam, Ellen Nalivaika, Nese Yilmaz, Celia Schiffer
Structural And Thermodynamic Basis Of Amprenavir/Darunavir And Atazanavir Resistance In Hiv-1 Protease With Mutations At Residue 50, Seema Mittal, Rajintha Bandaranayake, Nancy King, Moses Prabu-Jeyabalan, Madhavi Nalam, Ellen Nalivaika, Nese Yilmaz, Celia Schiffer
Celia A. Schiffer
Drug resistance occurs through a series of subtle changes that maintain substrate recognition but no longer permit inhibitor binding. In HIV-1 protease, mutations at I50 are associated with such subtle changes that confer differential resistance to specific inhibitors. Residue I50 is located at the protease flap tips, closing the active site upon ligand binding. Under selective drug pressure, I50V/L substitutions emerge in patients, compromising drug susceptibility and leading to treatment failure. The I50V substitution is often associated with amprenavir (APV) and darunavir (DRV) resistance, while the I50L substitution is observed in patients failing atazanavir (ATV) therapy. To explain how APV, …
Tca Cycle Inactivation In Staphylococcus Aureus Alters Nitric Oxide Production In Raw 264.7 Cells, Chandirasegaran Massilamany, Arunakumar Gangaplara, Donald Gardner, James Musser, David Steffen, Greg Somerville, Jay Reddy
Tca Cycle Inactivation In Staphylococcus Aureus Alters Nitric Oxide Production In Raw 264.7 Cells, Chandirasegaran Massilamany, Arunakumar Gangaplara, Donald Gardner, James Musser, David Steffen, Greg Somerville, Jay Reddy
Greg A. Somerville
Inactivation of the Staphylococcus aureus tricarboxylic acid (TCA) cycle delays the resolution of cutaneous ulcers in a mouse soft tissue infection model. In this study, it was observed that cutaneous lesions in mice infected with wild-type or isogenic aconitase mutant S. aureus strains contained comparable inflammatory infiltrates, suggesting the delayed resolution was independent of the recruitment of immune cells. These observations led us to hypothesize that staphylococcal metabolism can modulate the host immune response. Using an in vitro model system involving RAW 264.7 cells, the authors observed that cells cultured with S. aureus aconitase mutant strains produced significantly lower amounts …
Oral And Injectable Contraception Use And Risk Of Hiv Acquisition Among Women In Sub-Saharan Africa, Sandra Mccoy, Wenjing Zheng, Elizabeth Montgomery, Kelly Blanchard, Ariane Van Der Straten, Guy De Bruyn, Nancy Padian
Oral And Injectable Contraception Use And Risk Of Hiv Acquisition Among Women In Sub-Saharan Africa, Sandra Mccoy, Wenjing Zheng, Elizabeth Montgomery, Kelly Blanchard, Ariane Van Der Straten, Guy De Bruyn, Nancy Padian
Wenjing Zheng
OBJECTIVE:: Evaluate the effect of oral and injectable hormonal contraception (HC) on the risk of HIV acquisition among women in South Africa and Zimbabwe. DESIGN:: Secondary data analysis of 4913 sexually active women aged 18-49 years followed for up to 24 months in the MIRA phase III effectiveness trial of the diaphragm and lubricant gel for HIV prevention. METHODS:: Participants were interviewed quarterly about contraception and sexual behavior and were tested for pregnancy, HIV, and other sexually transmitted infections. We used a Cox proportional hazards marginal structural model, weighted by the inverse probability of HC use, to compare the risk …