Medicine and Health Sciences Commons^™

Aging: The Impact Of Diet And Inflammation, Morgan Wiland-Gress

Nursing Student Class Projects (Formerly MSN)

The immune system is a complex cohesive network. It requires every cell to work efficiently at maintaining homeostasis. It also prevents and repairs damage from internal and external pathogens. Recent research has focused on the concept of inflammaging, which is defined as age-related changes that occur in the immune system leading to dysfunction. The current understanding is that inflammaging contributes to the development of chronic diseases including; Type II Diabetes, Cardiovascular disease, Cancer, autoimmune disorders, neurological disorders, Alzheimer and Parkinson’s disease. The underlying pathophysiology of inflammaging is chronic inflammation and the imbalance of pro-inflammatory and anti-inflammatory mediators. This imbalance leads …

The Influence Of Stressful Life Events On The Development Of Type 2 Diabetes, Joshua Minks

Dissertations

This study examined the relationship between distress and the development of Type 2 diabetes mellitus (T2DM) in the presence of established risk factors. Distress secondary to mental health disparities, stressful life events, and work conditions has been shown to promote insulin resistance and the development of T2DM.

Subjects (N=79) diagnosed with T2DM within the previous six months were recruited from SSM Health Centers and VA Medical Centers in the greater St. Louis area. They completed the Recent Life Changes Questionnaire, ENRICHD Social Support Instrument, and a demographic survey and analyses were conducted to determine differences between the veteran …