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Full-Text Articles in Medicine and Health Sciences

Chemotherapy In Neuroendocrine/Merkel Cell Carcinoma Of The Skin: Case Series And Review Of 204 Cases, Patricia Tai, Edward Yu, Eric Winquist, Alex Hammond, Larry Stitt, Jan Tonita, Jim Gilchrist May 2000

Chemotherapy In Neuroendocrine/Merkel Cell Carcinoma Of The Skin: Case Series And Review Of 204 Cases, Patricia Tai, Edward Yu, Eric Winquist, Alex Hammond, Larry Stitt, Jan Tonita, Jim Gilchrist

Edward Yu

Purpose: To study the use of chemotherapy for Merkel cell carcinoma (MCC) of the skin. Patients and methods: Twenty-five cases of MCC were treated at the London Regional Cancer Center between 1987 and 1997. Thirteen cases treated with chemotherapy were reviewed with 191 cases from the literature. Results: At presentation, 24 patients had localized skin lesions (stage I) and one had locoregional involvement (stage II). Among the nine cases with recurrent nodal disease, six had chemotherapy as a component of salvage treatment. They were all free of disease at a median of 19 months (range, 12 to 37 months). In …


Radiation Treatment For Cervical Esophagus: Patterns Of Practice Study In Canada, 1996, Patricia Tai, Jake Van Dyk, Edward Yu, Jerry Battista, Matthew Schmid, Larry Stitt, Jon Tonita, Terry Coad May 2000

Radiation Treatment For Cervical Esophagus: Patterns Of Practice Study In Canada, 1996, Patricia Tai, Jake Van Dyk, Edward Yu, Jerry Battista, Matthew Schmid, Larry Stitt, Jon Tonita, Terry Coad

Edward Yu

PURPOSE: To assess the patterns of practice among Canadian radiation oncologists who treat esophageal cancers, using a trans-Canada survey, completed at the end of 1996. METHODS AND MATERIALS: One of 3 case presentations of different stages of cervical esophageal cancer was randomly assigned and sent to participating radiation oncologists by mail. Respondents were asked to fill in questionnaires regarding treatment techniques and to outline target volumes for the boost phase of radiotherapy. Radiation oncologists from 26 of 27 (96%) of all Canadian centers participated. RESULTS: High-energy X-rays (>/= 10 MV) were employed by 68% of the respondents in part …


How Much Asthma Is Occupationally Related?, David M. Mannino Apr 2000

How Much Asthma Is Occupationally Related?, David M. Mannino

David M. Mannino

Asthma is a chronic respiratory disease that is increasing in both prevalence and mortality in developed countries around the world. Occupational exposures to sensitizers and irritants are causes of both asthma cases and asthma exacerbations in adults. The determination of how many cases of asthma may be caused or worsened by occupational exposures is highly dependent on how asthma is defined, what constitutes work-relatedness, and what specific methodology is employed. Surveillance-based methods generally have found the lowest proportion of work-related asthma, ranging from 1-8% of cases. Other types of studies, using exposed-unexposed methodology or interviews of incident asthma cases, have …


Increasing Obesity In Brazil: Predicting A New Peak Of Cardiovascular Diseases, Paulo A. Lotufo Jan 2000

Increasing Obesity In Brazil: Predicting A New Peak Of Cardiovascular Diseases, Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.


Male Pattern Baldness And Coronary Heart Disease: The Physicians' Health Study, Paulo A. Lotufo Jan 2000

Male Pattern Baldness And Coronary Heart Disease: The Physicians' Health Study, Paulo A. Lotufo

Paulo A Lotufo

Is baldness a risk factor for heart attack? Aim: To examine the association between male pattern baldness and the risk of coronary heart disease (CHD) events. Desing, setting and participants:Retrospective cohort study among 22,071 US male physicians aged 40 to 84 years enrolled in the Physicians' Health Study. Of these, 19,112 were free of CHD at baseline and completed a questionnaire at the 11-year follow-up concerning their pattern of hair loss at age 45 years. Response options included no hair loss, frontal baldness only, or frontal baldness with mild, moderate, or severe vertex baldness. Main outcome measures: Coronary heart disease …


Moratoria Para A Crise Hipertensiva [Portuguese], Paulo A. Lotufo Jan 2000

Moratoria Para A Crise Hipertensiva [Portuguese], Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.


Alcohol Consumption And Risk Of Coronary Heart Disease By Diabetes Status, Paulo A. Lotufo Dec 1999

Alcohol Consumption And Risk Of Coronary Heart Disease By Diabetes Status, Paulo A. Lotufo

Paulo A Lotufo

Background—An inverse association between moderate alcohol consumption and coronary heart disease (CHD) has been observed in several epidemiological studies. To assess whether a similar association exists among diabetics, we examined the relation between light to moderate alcohol consumption and CHD in men with and without diabetes mellitus in a prospective cohort study. Methods and Results—A total of 87 938 US physicians (2790 with diagnosed diabetes mellitus) who were invited to participate in the Physicians’ Health Study and were free of myocardial infarction, stroke, cancer, or liver disease at baseline were followed for an average of 5.5 years for death with …