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Full-Text Articles in Medicine and Health Sciences

Hiv Risk Perception And Distribution Of Hiv Risk Among African, Caribbean And Other Black People: Mixed Methods Results From The Blacch Study, Shamara Baidoobonso, Greta Bauer, Kathy Speechley, Erica Lawson Nov 2012

Hiv Risk Perception And Distribution Of Hiv Risk Among African, Caribbean And Other Black People: Mixed Methods Results From The Blacch Study, Shamara Baidoobonso, Greta Bauer, Kathy Speechley, Erica Lawson

Shamara M Baidoobonso, PhD

Plain Language Summary: African, Caribbean and other Black people are a priority population for HIV prevention. This research found that perceptions about HIV risk in this population do not reflect actual risk. Furthermore, HIV risk behaviours in this population are more common among individuals with higher social standing. Background: African, Caribbean and other Black (ACB) people are a priority group for HIV prevention in Canada, but little is known about the epidemiology of HIV risk in this group. Furthermore, perceptions community members and service providers have about HIV risk may not reflect the overall distribution of risk in this population. …


Special Report: Hiv/Aids Service Needs Assessment, Shamara Baidoobonso, Roxanne Longman Marcellin, Leah Meidinger, Rob Haile, Harina Mokanan, Julius Ehiemua Oct 2012

Special Report: Hiv/Aids Service Needs Assessment, Shamara Baidoobonso, Roxanne Longman Marcellin, Leah Meidinger, Rob Haile, Harina Mokanan, Julius Ehiemua

Shamara M Baidoobonso, PhD

No abstract provided.


Maternal Concentrations Of Polyfluoroalkyl Compounds During Pregnancy And Fetal And Postnatal Growth In British Girls, Mildred Maisonet, Metrecia L. Terrell, Michael A. Mcgeehin, Krista Yorita Christensen, Adrianne Holmes, Antonia M. Calafat, Michele Marcus Sep 2012

Maternal Concentrations Of Polyfluoroalkyl Compounds During Pregnancy And Fetal And Postnatal Growth In British Girls, Mildred Maisonet, Metrecia L. Terrell, Michael A. Mcgeehin, Krista Yorita Christensen, Adrianne Holmes, Antonia M. Calafat, Michele Marcus

Mildred Maisonet

Background: Prenatal exposures to polyfluoroalkyl compounds (PFCs) may be associated with adverse changes in fetal and postnatal growth.
Objective: We explored associations of prenatal serum concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorohexane sulfonate (PFHxS) with fetal and postnatal growth in girls.

Methods: We studied a sample of 447 singleton girls and their mothers participating in the Avon Longitudinal Study of Parents and Children (ALSPAC). Data on weight and length were obtained at birth and at 2, 9, and 20 months. Serum samples were obtained in 1991–1992, from mothers during pregnancy. We explored associations between prenatal PFC concentrations and …


Highlighting Hiv-Related Results From The Black, African And Caribbean Canadian Health (Blacch) Study, Shamara Baidoobonso, Mercy Nleya-Ncube Sep 2012

Highlighting Hiv-Related Results From The Black, African And Caribbean Canadian Health (Blacch) Study, Shamara Baidoobonso, Mercy Nleya-Ncube

Shamara M Baidoobonso, PhD

No abstract provided.


Blacch Study E-Bulletin #2: Definition Of Health, Shamara Baidoobonso, Harina Mokanan Sep 2012

Blacch Study E-Bulletin #2: Definition Of Health, Shamara Baidoobonso, Harina Mokanan

Shamara M Baidoobonso, PhD

No abstract provided.


Big Data And The Future, Sherri Rose Jul 2012

Big Data And The Future, Sherri Rose

Sherri Rose

No abstract provided.


Blacch Study E-Bulletin #1: Executive Summary Of The Black, African And Caribbean Canadian Health (Blacch) Study, Shamara Baidoobonso, Greta Bauer, Mercy Nleya-Ncube Jul 2012

Blacch Study E-Bulletin #1: Executive Summary Of The Black, African And Caribbean Canadian Health (Blacch) Study, Shamara Baidoobonso, Greta Bauer, Mercy Nleya-Ncube

Shamara M Baidoobonso, PhD

No abstract provided.


Mortalidade Materna No Paraná: O Que Mostra A Produção Científica Nos Últimos 10 Anos? / Maternal Mortality In Paraná: Showing The Scientific Production In The Last 10 Years?, Everton Fernando Alves, Thais Abigail Vidoto Jun 2012

Mortalidade Materna No Paraná: O Que Mostra A Produção Científica Nos Últimos 10 Anos? / Maternal Mortality In Paraná: Showing The Scientific Production In The Last 10 Years?, Everton Fernando Alves, Thais Abigail Vidoto

Everton Fernando Alves

A mortalidade materna atrai inúmeras discussões e preocupações no Paraná visto que reflete a qualidade da assistência prestada nos serviços de saúde, bem como a operacionalização das políticas públicas voltadas à saúde da mulher. O objetivo deste trabalho foi conhecer o perfil epidemiológico da mortalidade materna no Estado do Paraná, por meio de revisão de estudos sobre o tema. Trata-se de uma revisão sistemática da literatura, realizada através da busca eletrônica de artigos científicos publicados entre 2000 e 2010, nas bases de dados LILACS e SciELO. Identificaram-se inicialmente 30 artigos. Após aplicação dos critérios de inclusão e exclusão restaram 09 …


Estimating The Impact Of Community-Level Interventions: The Search Trial And Hiv Prevention In Sub-Saharan Africa, Laura Balzer, Maya Petersen, Joshua Schwab, Mark Van Der Laan May 2012

Estimating The Impact Of Community-Level Interventions: The Search Trial And Hiv Prevention In Sub-Saharan Africa, Laura Balzer, Maya Petersen, Joshua Schwab, Mark Van Der Laan

Laura B. Balzer

Evaluation of community level interventions to prevent HIV infection presents significant methodological challenges. Even when it is feasible to randomly assign a treatment versus control level of the intervention to each community in a sample, measurement of incident HIV infection remains difficult. In this talk we describe an experimental design developed for the SEARCH Trial, a large community randomized trial that will evaluate the impact of expanded treatment on incident HIV and other outcomes. Regular community-wide testing campaigns are conducted and a random sample of community members who fail to attend a campaign are tracked. The data generated by this …


Why Match In Individually And Cluster Randomized Trials?, Laura B. Balzer, Maya L. Petersen, Mark J. Van Der Laan May 2012

Why Match In Individually And Cluster Randomized Trials?, Laura B. Balzer, Maya L. Petersen, Mark J. Van Der Laan

Laura B. Balzer

The decision to match individuals or clusters in randomized trials is motivated by both practical and statistical concerns. Matching protects against chance imbalances in baseline covariate distributions and is thought to improve study credibility. Matching is also implemented to increase study power. This article compares the asymptotic efficiency of the pair-matched design, where units are matched on baseline covariates and the treatment randomized within pairs, to the independent design, where units are randomly paired and the treatment randomized within pairs. We focus on estimating the average treatment effect and use the efficient influence curve to understand the information provided by …


Final Report From The Black, African And Caribbean Canadian Health (Blacch) Study, Shamara Baidoobonso, Harina Mokanan, Leah Meidinger, Daniel Pugh, Greta Bauer, Mercy Nleya-Ncube, Julius Ehiemua May 2012

Final Report From The Black, African And Caribbean Canadian Health (Blacch) Study, Shamara Baidoobonso, Harina Mokanan, Leah Meidinger, Daniel Pugh, Greta Bauer, Mercy Nleya-Ncube, Julius Ehiemua

Shamara M Baidoobonso, PhD

Originating in southwestern Ontario, the Black, African and Caribbean Canadian Health (BLACCH) Study began its work in 2009. The BLACCH Study is a mixed-methods community-based research project designed with the goal of improving health care access and the health status of Black people from Canada, Africa, the Caribbean and other parts of the world, who reside in London and Middlesex County, Ontario. The research team includes The University of Western Ontario, the Regional HIV/AIDS Connection, and the London Cross Cultural Learner Centre. The purpose behind this report is to shed light on the findings and outcomes that have emerged from …


Association Between Bilirubin And Cardiovascular Disease Risk Factors: Using Mendelian Randomization To Assess Causal Inference, Patrick F. Mcardle, Brian W. Whitcomb, Keith Tanner, Braxton D. Mitchell, Alan R. Shuldiner, Afshin Parsa Mar 2012

Association Between Bilirubin And Cardiovascular Disease Risk Factors: Using Mendelian Randomization To Assess Causal Inference, Patrick F. Mcardle, Brian W. Whitcomb, Keith Tanner, Braxton D. Mitchell, Alan R. Shuldiner, Afshin Parsa

Brian W. Whitcomb

Background: Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mendelian randomization has been proposed as a method to address challenges to validity from confounding and reverse causality. It utilizes genotype to estimate causal relationships between a gene product and physiological outcomes. In this report, we demonstrate its use in assessing direct causal relations between serum bilirubin levels and CVD risk factors, including obesity, cholesterol, measures of vascular function and blood pressure. Methods: Study subjects included 868 asymptomatic individuals. Study …


Acculturation And Gestational Weight Gain In A Predominantly Puerto Rican Population, Alison Tovar, Lisa Chasan-Taber, Odilia I. Bermudez, Raymond R. Hyatt, Aviva Must Dec 2011

Acculturation And Gestational Weight Gain In A Predominantly Puerto Rican Population, Alison Tovar, Lisa Chasan-Taber, Odilia I. Bermudez, Raymond R. Hyatt, Aviva Must

Lisa Chasan-Taber

Background Identifying risk factors that affect excess weight gain during pregnancy is critical, especially among women who are at a higher risk for obesity. The goal of this study was to determine if acculturation, a possible risk factor, was associated with gestational weight gain in a predominantly Puerto Rican population. Methods We utilized data from Proyecto Buena Salud, a prospective cohort study of Hispanic women in Western Massachusetts, United States. Height, weight and gestational age were abstracted from medical records among participants with full-term pregnancies (n=952). Gestational weight gain was calculated as the difference between delivery and prepregnancy weight. Acculturation …


Acculturation And Gestational Weight Gain In A Predominantly Puerto Rican Population, Alison Tovar, Lisa Chasan-Taber, Odilia I. Bermudez, Raymond R. Hyatt, Aviva Must Dec 2011

Acculturation And Gestational Weight Gain In A Predominantly Puerto Rican Population, Alison Tovar, Lisa Chasan-Taber, Odilia I. Bermudez, Raymond R. Hyatt, Aviva Must

Alison Tovar

Background Identifying risk factors that affect excess weight gain during pregnancy is critical, especially among women who are at a higher risk for obesity. The goal of this study was to determine if acculturation, a possible risk factor, was associated with gestational weight gain in a predominantly Puerto Rican population. Methods We utilized data from Proyecto Buena Salud, a prospective cohort study of Hispanic women in Western Massachusetts, United States. Height, weight and gestational age were abstracted from medical records among participants with full-term pregnancies (n=952). Gestational weight gain was calculated as the difference between delivery and prepregnancy weight. Acculturation …