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Key Players In Reverse Cholesterol Transport: The Plasma Enzyme Lcat, Christopher J. Pechura
Key Players In Reverse Cholesterol Transport: The Plasma Enzyme Lcat, Christopher J. Pechura
Undergraduate Research Posters 2012
Lecithin cholesterol acyltransferase (LCAT) is a plasma enzyme that remodels nascent high density lipoprotein (HDL) into a mature form called spherical HDL. The model will be used in the future to map the amino acid residues from LCAT and the protein component of nascent HDL (apoA1) involved in mutual interaction, and to identify LCAT residues interacting with the lipid phase of nascent HDL.