Medicine and Health Sciences Commons^™

Synergistic Induction Of Ahr Regulated Genes In Developmental Toxicity From Co-Exposure To Two Model Pahs In Zebrafish, Alicia R. Timme-Laragy, Crystal J. Cockman, Cole W. Matson, Richard T. Di Giulio

Alicia R. Timme-Laragy

Polycyclic aromatic hydrocarbons (PAHs) are pollutants created by the incomplete combustion of carbon, and are increasing in the environment largely due to the burning of fossil fuels. PAHs occur as complex mixtures, and some combinations have been shown to cause synergistic developmental toxicity in fish embryos, characterized by pericardial edema and craniofacial malformations. Previous studies have indicated that in the zebrafish model, this toxicity is mediated by the aryl hydrocarbon receptor 2 (AHR2), and enhanced by inhibition of CYP1A activity. In this study, we further examined this interaction of the model PAH and AHR agonist β-naphthoflavone (BNF) with and without …

Rural Utility Cooperative (Ruc) Final Evaulation Report: Alaska Native Tribal Health Consortium (Anthc), R. Konkel

Steve Konkel

The Rural Utility Cooperative (RUC) Final Evaluation is designed to answer several interrelated

questions:

• Is the RUC working as envisioned?

• Is it making an impact in the RUC Communities?

• Are the RUC Communities better off than the Non-RUC communities?

Strategic Planning For Environmental Stewardship At Eastern Kentucky University, Steven Konkel, Dr. Robert Weise, Dr. Alan Banks, Dr. Danita Lasage, Professor Joseph Beck, James Street, Dr. Charles Elliott, Professor Barbara Szubinska, Dr. Robert Frederick, Dr. Melinda Wilder, Dr. Robert Huston, Rebecca Jones, Dr. Alice Jones, Kyle Moon

Steve Konkel

The 2006-2010 Strategic Plan for Eastern Kentucky University, under Strategic Direction 5.4, mandates the formulation of a plan to guide the University toward greater environmental stewardship. The creation and implementation of that plan is the charge of the Eastern Committee on Responsible Environmental Stewardship (ECRES), which was formed in September of 2005. On October 27th, 2006, ECRES hosted a Strategic Planning Workshop. This workshop brought together a wide range of paticipants, including elected officials, college and university representatives, and interested citizens. The result was a broad consenus in the identification of environmental goals and objectives toward which EKU should strive.

No Evidence For Acid-Catalyzed Secondary Organic Aerosol Formation In Power Plant Plumes Over Metropolitan Atlanta, Georgia, Richard E. Peltier, A. P. Sullivan, R. J. Weber, A. G. Wollny, J. S. Holloway, C. A. Brock, J. A. De Gouw, E. L. Atlas

Richard E. Peltier

Aircraft-based measurements of the water-soluble fraction of fine PM organic carbon (WSOC) and inorganic salt composition in the Atlanta, GA region were conducted in the summer of 2004. Five notable plumes of SO2, apparently from coal-fired power plants, were intercepted, and had NH4 +/SO42 molar ratios ranging from approximately 0.8 to 1.4 compared to molar ratios near 2 outside of the plumes. Sulfate aerosol concentrations increased from a regional background of 5–8 mg m 3 to as high as 19.5 mg m 3 within these plumes. No increase in WSOC concentrations was observed in plumes compared to out-of plumes within …

Determining Client Need In A Multi-State Fetal Alcohol Syndrome Consortium: From Training To Practice, Suzanne Christopher, Tim Dunnagan, George Haynes, Lili Stiff

Tim Dunnagan

Background: A multi-state consortium was developed in the US to conduct baseline data collection and intervention research on fetal alcohol syndrome. Each state employed support specialists whose job it was to reduce or eliminate alcohol consumption in women who were at high risk for drinking alcohol during their pregnancy. The purpose of this paper is to report how support specialists in three primarily rural/frontier states were trained to assess client need and how client need was actually assessed in the field.

Methods: A qualitative process evaluation was conducted using semi-structured interviews. Interviews were conducted with state staff involved in support …