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Survey Of Histoplasma Capsulatum In Bat Guano And Status Of Histoplasmosis In Slovenia, Central Europe, Janez Mulec, Saša Simčič, Tadeja Kotar, Romina Kofol, Sanja Stopinšek
Survey Of Histoplasma Capsulatum In Bat Guano And Status Of Histoplasmosis In Slovenia, Central Europe, Janez Mulec, Saša Simčič, Tadeja Kotar, Romina Kofol, Sanja Stopinšek
International Journal of Speleology
There have been increasing reports on the presence of Histoplasma capsulatum in some European countries. The study investigated the presence of Histoplasma in bat guanos, speleologists with records of visiting Histoplasma-endemic regions and patients with histoplasmosis. A commercial ALPHA Histoplasma Antigen enzyme immunoassay was tested as an alternative methodology to detect Histoplasma in environment and compared with polymerase chain reaction (PCR) assays. The presence of Histoplasma antigen in bat guanos was not confirmed by PCR. Among 14 healthy speleologists, two were indicated as having the Histoplasma antigen in urine, but expressed negative PCR-specific results for the Histoplasma antigen. Five …