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Effect Of Strong Electrolyte Containing Gelling Aids On The Sol-Gel Transition Temperature Of Hypromellose 2910, Elnaz Sadeghi
Effect Of Strong Electrolyte Containing Gelling Aids On The Sol-Gel Transition Temperature Of Hypromellose 2910, Elnaz Sadeghi
Biomedical Engineering ETDs
Hypromellose, or hydroxypropyl methylcellulose (HPMC) - has been widely used for biomedical and pharmaceutical applications due to its advantages, including that it is modifiable in terms of viscosity, and it has the ability to form thermally reversible hydrogels. The thermal gelation temperature (TGel) of a given HPMC solution strongly depends on its characteristic grade and the solution concentration. Applying certain additives can modify the TGel even further; depending on their nature and concentration. With the addition of said additives, a lower or higher TGel can be obtained. For example, the addition of sodium chloride (NaCl) reduces …