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Full-Text Articles in Medicine and Health Sciences

Evaluating The Toxicity And Formation Of Halobenzoquinones In Point-Of-Use Chlorinated Drinking Water, Stephanie Hung Oct 2018

Evaluating The Toxicity And Formation Of Halobenzoquinones In Point-Of-Use Chlorinated Drinking Water, Stephanie Hung

Masters Theses

Chlorine has effectively reduced the prevalence of waterborne diseases, however there are secondary consequences to this public health advancement. Disinfection byproducts (DBPs) are chemicals formed when chlorine reacts with natural organic matter (NOM) in water. A new class of DBPs, halobenzoquinones (HBQs), has recently been identified and data suggests it could be potentially carcinogenic and up to 1000 times more toxic than some regulated DBPs. So far, in vitro studies have assessed HBQ toxicity without taking into account its transformation in cell media into potentially less toxic compounds. This study evaluated the toxic effects of one HBQ, 2,6-DCBQ, and its …


Role Of Rigidity And Flexibility Of Functional Groups Within The Interior Of Supramolecular Assemblies And Their Implications, Oyuntuya Munkhbat Mar 2018

Role Of Rigidity And Flexibility Of Functional Groups Within The Interior Of Supramolecular Assemblies And Their Implications, Oyuntuya Munkhbat

Doctoral Dissertations

Engineering of supramolecular assemblies at molecular level renders functional nanomaterials that present explicit response to certain environmental changes. Systematic structure-property correlation studies will unravel the fundamental design constraints of these functional nanomaterials that fulfill the emergent need. This dissertation will primarily focus on understanding the role of rigidity and flexibility of functional groups within amphiphilic assemblies and employing this basic concept in drug delivery and diagnostics applications. Supramolecular assemblies formed by amphiphilic dendrimers and polymers are preferred for this study as they exhibit high thermodynamic stability and structural flexibility. The role of aromatic interaction on the unimer-aggregate dynamic equilibrium was …


Syllabus: Drinking Water, Sanitation, And Global Development, Emily Kumpel Jan 2018

Syllabus: Drinking Water, Sanitation, And Global Development, Emily Kumpel

Sustainability Education Resources

Within the past three decades, more than 2.6 billion people have gained access to an improved water source and 2.1 billion have gained access to an improved sanitation facility. However, improved does not always mean people have safe, reliable, accessible, or equitable water and sanitation services. Waterborne diseases continue to cause and estimated 500,000 deaths each year. What causes waterborne diseases, and what is the role of engineered systems in their spread or prevention? How can we evaluate interventions to improve health and well-being? How can research address these challenges?


Brain Science = Biology + Engineering, Jennifer Welborn, Guangyu Xu, Morton Sternheim, Chris Emery Jan 2018

Brain Science = Biology + Engineering, Jennifer Welborn, Guangyu Xu, Morton Sternheim, Chris Emery

Science and Engineering Saturday Seminars

This interdisciplinary (physical and life sciences) seminar exposes participants to cutting edge research at UMASS, Amherst, on cell imaging using a chip which gathers a variety of data on the activities of single cells. Part of the seminar will be a presentation of current research in this area, followed by hands-on activities and a visit to the lab where this research is conducted. Application of this new technology to brain research will be discussed as well as the NGSS standards alignment and classroom applications at various levels and disciplines.