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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Engineering

University of Texas Rio Grande Valley

2023

Microneedle

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Full-Text Articles in Medicine and Health Sciences

A 3d Printed Microneedle System For Transdermal Drug Delivery Of Anticancer Drugs, Md Jasim Uddin, Tanvir Ahmed, Dennis Douroumis Sep 2023

A 3d Printed Microneedle System For Transdermal Drug Delivery Of Anticancer Drugs, Md Jasim Uddin, Tanvir Ahmed, Dennis Douroumis

Research Symposium

Background: Transdermal delivery of drugs is an attractive alternative to the conventional route of administration as oral delivery. The hypodermic injections are painful and less patient compliance. Microneedles (MNs) are micron-sized, minimally invasive needles to deliver a wide range of molecules (e.g., small, DNA, vaccines etc.) to the upper portion of the dermis in a sustained and controlled manner, without causing any pain. The introduction of 3D printing technologies in the fabrication of MN will promote one-step manufacturing tools and scale-up for the delivery devices of anticancer drugs.

Methods: The 3D printed MN (3DMN) arrays were fabricated using Stereolithography (SLA), …