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Full-Text Articles in Medicine and Health Sciences

Opportunities For Research In Mental Health Emergencies: Executive Summary And Methodology, M. P. Wilson, C. Shenvi, L. Rives, K. Nordstrom, S. Schneider, M. Gerardi Jan 2019

Opportunities For Research In Mental Health Emergencies: Executive Summary And Methodology, M. P. Wilson, C. Shenvi, L. Rives, K. Nordstrom, S. Schneider, M. Gerardi

Journal Articles

© 2019 Wilson et al. Introduction: Despite the ever-increasing numbers of mental health patients presenting to United States emergency departments, there are large gaps in knowledge about acute care of the behavioral health patient. To address this important problem, the Coalition on Psychiatric Emergencies convened a research consensus conference in December 2016 consisting of clinical researchers, clinicians from emergency medicine, psychiatry and psychology, and representatives from governmental agencies and patient advocacy groups. Methods: Participants used a standardized methodology to select and rank research questions in the order of importance to both researchers and patients. Results: Three working groups (geriatrics, substance …


Integration Of Entrustable Professional Activities With The Milestones For Emergency Medicine Residents, D. Hart, D. Franzen, M. Beeson, R. Bhat, M. Kulkarni, L. Thibodeau, M. Weizberg, S. Promes Jan 2019

Integration Of Entrustable Professional Activities With The Milestones For Emergency Medicine Residents, D. Hart, D. Franzen, M. Beeson, R. Bhat, M. Kulkarni, L. Thibodeau, M. Weizberg, S. Promes

Journal Articles

© 2019 Hart et al. Introduction: Medical education is moving toward a competency-based framework with a focus on assessment using the Accreditation Council for Graduate Medical Education Milestones. Assessment of individual competencies through milestones can be challenging. While competencies describe characteristics of the person, the entrustable professional activities (EPAs) concept refers to work-related activities. EPAs would not replace the milestones but would be linked to them, integrating these frameworks. Many core specialties have already defined EPAs for resident trainees, but EPAs have not yet been created for emergency medicine (EM). This paper describes the development of milestone-linked EPAs for EM. …


Standardized Video Interviews Do Not Correlate To United States Medical Licensing Examination Step 1 And Step 2 Scores, D. J. Egan, A. Husain, M. C. Bond, W. Caputo, L. Cygan, J. Van Dermark, J. M. Shoenberger, I. Li, B. Ardolic, M. Weizberg, +7 Additional Authors Jan 2019

Standardized Video Interviews Do Not Correlate To United States Medical Licensing Examination Step 1 And Step 2 Scores, D. J. Egan, A. Husain, M. C. Bond, W. Caputo, L. Cygan, J. Van Dermark, J. M. Shoenberger, I. Li, B. Ardolic, M. Weizberg, +7 Additional Authors

Journal Articles

© 2019 Egan et al. Introduction: In 2017, the Standardized Video Interview (SVI) was required for applicants to emergency medicine (EM). The SVI contains six questions highlighting professionalism and interpersonal communication skills. The responses were scored (6-30). As it is a new metric, no information is available on correlation between SVI scores and other application data. This study was to determine if a correlation exists between applicants' United States Medical Licensing Examination (USMLE) and SVI scores. We hypothesized that numeric USMLE Step 1 and Step 2 Clinical Knowledge (CK) scores would not correlate with the SVI score, but that performance …


Simulation-Based Remediation In Emergency Medicine Residency Training: A Consensus Study, N. A. Nadir, D. Hart, M. Cassara, J. Noelker, T. Moadel, M. Kulkarni, C. S. Sampson, S. Bentley, N. K. Naik, C. Strother, +4 Additional Authors Jan 2019

Simulation-Based Remediation In Emergency Medicine Residency Training: A Consensus Study, N. A. Nadir, D. Hart, M. Cassara, J. Noelker, T. Moadel, M. Kulkarni, C. S. Sampson, S. Bentley, N. K. Naik, C. Strother, +4 Additional Authors

Journal Articles

© 2019 Nadir et al. Introduction: Resident remediation is a pressing topic in emergency medicine (EM) training programs. Simulation has become a prominent educational tool in EM training and been recommended for identification of learning gaps and resident remediation. Despite the ubiquitous need for formalized remediation, there is a dearth of literature regarding best practices for simulation-based remediation (SBR). Methods: We conducted a literature search on SBR practices using the terms "simulation," "remediation," and "simulation based remediation." We identified relevant themes and used them to develop an open-ended questionnaire that was distributed to EM programs with experience in SBR. Thematic …


Enhanced Macrophage Pannexin 1 Expression And Hemichannel Activation Exacerbates Lethal Experimental Sepsis, W. Chen, S. Zhu, Y. Wang, J. Li, X. Qiang, X. Zhao, L. Becker, P. Wang, K. J. Tracey, H. Wang, +2 Additional Authors Jan 2019

Enhanced Macrophage Pannexin 1 Expression And Hemichannel Activation Exacerbates Lethal Experimental Sepsis, W. Chen, S. Zhu, Y. Wang, J. Li, X. Qiang, X. Zhao, L. Becker, P. Wang, K. J. Tracey, H. Wang, +2 Additional Authors

Journal Articles

No abstract provided.


A Research Agenda For Assessment And Management Of Psychosis In Emergency Department Patients, J. Peltzer-Jones, K. Nordstrom, G. Currier, J. S. Berlin, C. Singh, S. Schneider Jan 2019

A Research Agenda For Assessment And Management Of Psychosis In Emergency Department Patients, J. Peltzer-Jones, K. Nordstrom, G. Currier, J. S. Berlin, C. Singh, S. Schneider

Journal Articles

© 2019 Peltzer-Jones et al. Introduction: Emergency departments (ED) manage a wide variety of critical medical presentations. Traumatic, neurologic, and cardiac crises are among the most prevalent types of emergencies treated in an ED setting. The high volume of presentations has led to collaborative partnerships in research and process development between experts in emergency medicine (EM) and other disciplines. While psychosis is a medical emergency frequently treated in the ED, there remains a paucity of evidence-based literature highlighting best practices for management of psychotic presentations in the ED. In the absence of collaborative research, development of best practice guidelines cannot …


Incoming Interns Perceived Preparedness For Core Entrustable Professional Activities, R. E. Pearlman, M. A. Pawelczak, J. B. Bird, A. C. Yacht, G. A. Farina Jan 2019

Incoming Interns Perceived Preparedness For Core Entrustable Professional Activities, R. E. Pearlman, M. A. Pawelczak, J. B. Bird, A. C. Yacht, G. A. Farina

Journal Articles

© 2019, International Association of Medical Science Educators. Introduction: The AAMC described 13 core entrustable professional activities (EPAs) for which every graduating medical student should perform proficiently on day 1 of residency. We studied how prepared starting interns felt in the core EPAs. Methods: Interns from a diverse health system were surveyed on how well medical school prepared them in the 13 core EPAs. Data were collected on type of medical school, participation in an acting/sub-internship (AI/SI), knowledge of EPAs, and participation in an EPA experience. Results: We collected 224 surveys out of 384 (58%) interns. 61.2% attended allopathic, 14.6% …


Free Open Access Medical Education Applications: A Critical Appraisal Of Techniques For Quality Assessment And Content Discovery, A. Zhi, A. Husain Jan 2019

Free Open Access Medical Education Applications: A Critical Appraisal Of Techniques For Quality Assessment And Content Discovery, A. Zhi, A. Husain

Journal Articles

No abstract provided.


Assessment Of Physician Well-Being, Part Two: Beyond Burnout, M. D. Lall, T. J. Gaeta, A. S. Chung, S. A. Chinai, M. Garg, A. Husain, C. Kanter, S. Khandelwal, C. S. Rublee, N. T. Himelfarb, +3 Additional Authors Jan 2019

Assessment Of Physician Well-Being, Part Two: Beyond Burnout, M. D. Lall, T. J. Gaeta, A. S. Chung, S. A. Chinai, M. Garg, A. Husain, C. Kanter, S. Khandelwal, C. S. Rublee, N. T. Himelfarb, +3 Additional Authors

Journal Articles

© 2019 Lall et al. Part One of this two-article series reviews assessment tools to measure burnout and other negative states. Physician well-being goes beyond merely the absence of burnout. Transient episodes of burnout are to be expected. Measuring burnout alone is shortsighted. Well-being includes being challenged, thriving, and achieving success in various aspects of personal and professional life. In this second part of the series, we identify and describe assessment tools related to wellness, quality of life, resilience, coping skills, and other positive states.


Does Training Level Affect The Accuracy Of Visual Assessment Of Capillary Refill Time?, K. Shinozaki, L. S. Jacobson, K. Saeki, N. Kobayashi, S. Weisner, J. M. Falotico, T. Li, J. Kim, J. W. Lampe, L. B. Becker Jan 2019

Does Training Level Affect The Accuracy Of Visual Assessment Of Capillary Refill Time?, K. Shinozaki, L. S. Jacobson, K. Saeki, N. Kobayashi, S. Weisner, J. M. Falotico, T. Li, J. Kim, J. W. Lampe, L. B. Becker

Journal Articles

No abstract provided.


Camp Metabolism Controls Caspase-11 Inflammasome Activation And Pyroptosis In Sepsis, R. Chen, L. Zeng, S. Zhu, J. Liu, H. J. Zeh, G. Kroemer, H. Wang, T. R. Billiar, J. Jiang, R. Kang, +1 Additional Author Jan 2019

Camp Metabolism Controls Caspase-11 Inflammasome Activation And Pyroptosis In Sepsis, R. Chen, L. Zeng, S. Zhu, J. Liu, H. J. Zeh, G. Kroemer, H. Wang, T. R. Billiar, J. Jiang, R. Kang, +1 Additional Author

Journal Articles

No abstract provided.


Recent Advances In Personalizing Cardiac Arrest Resuscitation, C. E. Kuschner, L. B. Becker Jan 2019

Recent Advances In Personalizing Cardiac Arrest Resuscitation, C. E. Kuschner, L. B. Becker

Journal Articles

© 2019 Kuschner CE and Becker LB. Cardiac arrest remains a significant cause of death and disability throughout the world. However, as our understanding of cardiac arrest and resuscitation physiology has developed, new technologies are fundamentally altering our potential to improve survival and neurologic sequela. Some advances are relatively simple, requiring only alterations in current basic life support measures or integration with pre-hospital organization, whereas others, such as extra-corporeal membrane oxygenation, require significant time and resource investments. When combined with consistent rescuer and patient-physiologic monitoring, these innovations allow an unprecedented capacity to personalize cardiac arrest resuscitation to patient-specific pathophysiology. However, …


A Pilot Study Of Respiratory Rate Derived From A Wearable Biosensor Compared With Capnography In Emergency Department Patients, T. Li, S. Divatia, J. Mckittrick, J. Moss, N. M. Hijnen, L. B. Becker Jan 2019

A Pilot Study Of Respiratory Rate Derived From A Wearable Biosensor Compared With Capnography In Emergency Department Patients, T. Li, S. Divatia, J. Mckittrick, J. Moss, N. M. Hijnen, L. B. Becker

Journal Articles

© 2019 Li et al. Purpose: Respiratory rate is assessed less frequently than other vital signs, and documented respiratory rates are often erroneous. This pilot study compared respiratory rates derived from a wearable biosensor to those derived from capnography. Methods: Emergency department patients with respiratory complaints were enrolled and had capnography via nasal cannula and a wireless, wearable biosensor from Philips applied for approximately one hour. Respiratory rates were obtained from both of these methods. We determined the difference between median respiratory rates obtained from the biosensor and capnography and the proportion of biosensor-derived respiratory rates that were within three …


Sexual Dimorphism Of Gut Microbiota Dictates Therapeutics Efficacy Of Radiation Injuries, M. Cui, H. Xiao, Y. Li, S. Zhang, J. Dong, B. Wang, C. Zhu, M. Jiang, H. Wang, S. Fan, +2 Additional Authors Jan 2019

Sexual Dimorphism Of Gut Microbiota Dictates Therapeutics Efficacy Of Radiation Injuries, M. Cui, H. Xiao, Y. Li, S. Zhang, J. Dong, B. Wang, C. Zhu, M. Jiang, H. Wang, S. Fan, +2 Additional Authors

Journal Articles

© 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Accidental or iatrogenic ionizing radiation exposure precipitates acute and chronic radiation injuries. The traditional paradigm of mitigating radiotherapy-associated adverse side effects has ignored the gender-specific dimorphism of patients' divergent responses. Here, the effects of sexual dimorphism on curative efficiencies of therapeutic agents is examined in murine models of irradiation injury. Oral gavage of simvastatin ameliorates radiation-induced hematopoietic injury and gastrointestinal tract dysfunction in male mice, but adversely deteriorates these radiation syndromes in female animals. In a sharp contrast, feeding animals with high-fat diet (HFD) elicites explicitly contrary …


How Well Does The Standardized Video Interview Score Correlate With Traditional Interview Performance?, A. S. Chung, K. H. Shah, M. Bond, B. Ardolic, A. Husain, I. Li, L. Cygan, W. Caputo, J. Shoenberger, M. Weizberg, +2 Additional Authors Jan 2019

How Well Does The Standardized Video Interview Score Correlate With Traditional Interview Performance?, A. S. Chung, K. H. Shah, M. Bond, B. Ardolic, A. Husain, I. Li, L. Cygan, W. Caputo, J. Shoenberger, M. Weizberg, +2 Additional Authors

Journal Articles

© 2019 Chung et al. Introduction: In 2017, all medical students applying for residency in emergency medicine (EM) were required to participate in the Standardized Video Interview (SVI). The SVI is a video-recorded, unidirectional interview consisting of six questions designed to assess interpersonal and communication skills and professionalism. It is unclear whether this simulated interview is an accurate representation of an applicant’s competencies that are often evaluated during the in-person interview. Objective: The goal of this study was to determine whether the SVI score correlates with a traditional in-person interview score. Methods: Six geographically and demographically diverse EM residency programs …


Caspase-11 Signaling Enhances Graft-Versus-Host Disease, Y. Lu, R. Meng, X. Wang, Y. Xu, Y. Tang, J. Wu, Q. Xue, S. Yu, H. Wang, B. Lu Jan 2019

Caspase-11 Signaling Enhances Graft-Versus-Host Disease, Y. Lu, R. Meng, X. Wang, Y. Xu, Y. Tang, J. Wu, Q. Xue, S. Yu, H. Wang, B. Lu

Journal Articles

No abstract provided.