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Full-Text Articles in Medicine and Health Sciences

Stem Cell Matching For Patients Of Mixed Race, Ted C. Bergstrom Dec 2009

Stem Cell Matching For Patients Of Mixed Race, Ted C. Bergstrom

Ted C Bergstrom

Patients with leukemia and other blood diseases stand a good chance of recovery and a return to normal life if they receive a stem cell transplant from a living donor. In the absence of a transplant, their survival prospects are grim. For a transplant to be successful, the human leukocyte antigens (HLA) of the donor and recipient must be a close genetic match. To facilitate non-sibling matches, the developed nations of the world have set up national volunteer registries. The larges such registry is the NMDP (National Marrow Donor Program). We estimate the distribution of HLA types for individuals of …


Community Demographics And Access To Care Among Us Hispanics, Carole Gresenz, J. Rogowski, Jose Escarce Sep 2009

Community Demographics And Access To Care Among Us Hispanics, Carole Gresenz, J. Rogowski, Jose Escarce

Carole Roan Gresenz

No abstract provided.


One Chance In A Million: Altruism And The Bone Marrow Registry, Ted Bergstrom, Rod Garratt, Damien Sheehan-Connor Aug 2009

One Chance In A Million: Altruism And The Bone Marrow Registry, Ted Bergstrom, Rod Garratt, Damien Sheehan-Connor

Ted C Bergstrom

Transplants of donated stem cells save the lives of many patients with blood diseases. Donation is somewhat painful, butrarely has lasting adverse effects. Patients can accept transplants only from donors with compatible immune systems. Those lacking a sibling match must seek donations from the population at large. The probability that two persons of the same race are compatible is less than 1/10,000. Health authorities maintain a registry of several million genetically-tested potential donors who have agreed to donate if asked. We study the peculiar structure of voluntary public good provision represented by the registry, and compare the marginal benefits and …


Public Health H1n1 Response Research Protocol, Glen Mays Jul 2009

Public Health H1n1 Response Research Protocol, Glen Mays

Glen Mays

This research protocol was developed to analyze local variation in the public health response to the 2009 H1N1 influenza outbreak in the United States. The protocol was fielded in North Carolina and Kentucky through practice-based research networks (PBRNs) operating in these states.


Opportunities For Comparative Research In Public Health Pbrns: A Baseline Analysis Of Local Practice Settings, Glen P. Mays, Sharla A. Smith Jun 2009

Opportunities For Comparative Research In Public Health Pbrns: A Baseline Analysis Of Local Practice Settings, Glen P. Mays, Sharla A. Smith

Glen Mays

This anaysis describes the organizational and operational characteristics of local public health agencies participating in an initial cohort of five (5) public health PBRNs in the U.S. We examine variation in practice settings within and between PBRNs; compare practice settings to state and national norms; and identify opportunities for comparative research that can be conducted through PBRNs


Initial Research And Evaluation Concepts For Public Health Pbrns, Glen Mays Feb 2009

Initial Research And Evaluation Concepts For Public Health Pbrns, Glen Mays

Glen Mays

Initial research and evaluation activities of the Public Health PBRN Program are intended to provide a descriptive characterization of networks during their early stages of development. This descriptive ‘network analysis’ will provide a baseline for tracking changes in network structure and function over time. The information generated through these activities is intended to be useful for a variety of audiences, including current grantees and others interested in developing or expanding public health PBRNs, as well as policy and practice stakeholders interested in using the evidence and insight to be produced through PBRNs.


The Benefits Of Risk Factor Prevention In Americans Aged 51 Years And Older, Dana P. Goldman, Yuhui Zheng, Federico Girosi, Pierre-Carl Michaud, S. Jay Olshansky, David Cutler, John W. Rowe Jan 2009

The Benefits Of Risk Factor Prevention In Americans Aged 51 Years And Older, Dana P. Goldman, Yuhui Zheng, Federico Girosi, Pierre-Carl Michaud, S. Jay Olshansky, David Cutler, John W. Rowe

Yuhui Zheng

Objectives. We assessed the potential health and economic benefits of reducing common risk factors in older Americans.

Methods. A dynamic simulation model tracked a national cohort of persons 51 and 52 years of age to project their health and medical spending in prevention scenarios for diabetes, hypertension, obesity, and smoking.

Results. The gain in life span from successful treatment of a person aged 51 or 52 years for obesity would be 0.85 years; for hypertension, 2.05 years; and for diabetes, 3.17 years. A 51- or 52-year-old person who quit smoking would gain 3.44 years. Despite living longer, those successfully treated …


Understanding The Economic Consequences Of Shifting Trends In Population Health, Pierre-Carl Michaud, Dana P. Goldman, Darius N. Lakdawalla, Yuhui Zheng, Adam Gailey Jan 2009

Understanding The Economic Consequences Of Shifting Trends In Population Health, Pierre-Carl Michaud, Dana P. Goldman, Darius N. Lakdawalla, Yuhui Zheng, Adam Gailey

Yuhui Zheng

No abstract provided.


International Differences In Longevity And Health And Their Economic Consequences, Pierre-Carl Michaud, Dana P. Goldman, Darius N. Lakdawalla, Adam Gailey, Yuhui Zheng Jan 2009

International Differences In Longevity And Health And Their Economic Consequences, Pierre-Carl Michaud, Dana P. Goldman, Darius N. Lakdawalla, Adam Gailey, Yuhui Zheng

Yuhui Zheng

No abstract provided.


Start-Up Activities For Public Health Pbrns, Glen Mays Jan 2009

Start-Up Activities For Public Health Pbrns, Glen Mays

Glen Mays

Launching a successful public health practice-based research network requires a planned approach to developing the necessary infrastructure, relationships, and scientific direction.


Anemia In Low-Income Countries Is Unlikely To Be Addressed By Economic Development Without Additional Programs, Sebastian Linnemayr, Harold Alderman Dec 2008

Anemia In Low-Income Countries Is Unlikely To Be Addressed By Economic Development Without Additional Programs, Sebastian Linnemayr, Harold Alderman

Sebastian Linnemayr

Although governments may decline to invest in iron fortification or supplementation influenced by the view that income growth will address the problem, the data do not support this view. Looking at the rates of anemia among children and adult women across 40 Demographic and Health Surveys from 32 countries, this study found that although anemia rates do decrease as income increases, the decrease is modest. Indeed, overall anemia rates decline roughly a quarter as fast as income increases and at only half the speed at which rates of underweight decline.


Zoning For Health? The Year-Old Ban On New Fast-Food Restaurants In South La, Roland Sturm, Deborah Cohen Dec 2008

Zoning For Health? The Year-Old Ban On New Fast-Food Restaurants In South La, Roland Sturm, Deborah Cohen

Roland Sturm

No abstract provided.


Affordability And Obesity: Issues In The Multifunctionality Of Agricultural/Food Systems, Roland Sturm Dec 2008

Affordability And Obesity: Issues In The Multifunctionality Of Agricultural/Food Systems, Roland Sturm

Roland Sturm

No abstract provided.