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Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Developing A Virus-Like Particle (Vlp)-Based Vaccine For Neisseria Gonorrhoeae, Ashvini Vaidya
Developing A Virus-Like Particle (Vlp)-Based Vaccine For Neisseria Gonorrhoeae, Ashvini Vaidya
Biomedical Sciences ETDs
Neisseria gonorrhoeae (Ng) is a sexually transmitted bacterium that infects human reproductive mucosal surfaces. Due to the risk of complications in untreated cases and evolving antibiotic resistance, a prophylactic vaccine is critical for preventing infection. There are four Ng outer-membrane proteins that contribute to Ng survival and resistance: PorB, BamA, TbpA, and MtrE. Each protein contains surface-exposed loops that are targets of bactericidal antibodies. Vaccines were developed by displaying Ng epitopes on the surface of bacteriophage virus-like particles (VLP). VLPs are immunogenic, multivalent, self-assembling complexes composed of viral structural proteins. Antigenic peptide sequences can be displayed on the surface …
A Review Of Major Role Of Vitamin D3 In Human Immune System And Its Possible Use For Novel Corona Virus Treatment, Florentin Smarandache, Victor Christianto
A Review Of Major Role Of Vitamin D3 In Human Immune System And Its Possible Use For Novel Corona Virus Treatment, Florentin Smarandache, Victor Christianto
Branch Mathematics and Statistics Faculty and Staff Publications
the evidences showing major role of Vitamin D3 in human immune system and its potential use for novel corona virus treatment. Our argument is based on research finding that corona virus has viral envelope glycoproteins. In this regard, Vitamin D3 proves to offer various beneficial effects, including immunomodulatory effect, in order to break the glycoproteins envelope of the virus. One of the greatest benefit of vitamin D3 is the fact that it is easy to get 10,000 - 20,000 IU of daily intake requirement, by sunbathing for more or less twenty minutes. Such a method is likely applicable in many …
Evolutionary Ecology Of Host-Parasite Relationships: Role Of Host Ecology, Phylogeny, And Demographics In Shaping Parasite Evolution, Erika Taylor Gendron
Evolutionary Ecology Of Host-Parasite Relationships: Role Of Host Ecology, Phylogeny, And Demographics In Shaping Parasite Evolution, Erika Taylor Gendron
Biology ETDs
Host-parasite systems exist across complex and ecologically heterogeneous landscapes, and may occur across taxonomically and ecologically disparate host species. Under these conditions, mechanisms underlying microevolutionary processes (i.e. gene flow, genetic drift) are not always clear, and may be mediated by numerous co-occurring factors specific to individual hosts. Host traits such as host immunology, demographics, phylogeny and ecology may act in concert to shape host-parasite relationships, and ultimately evolutionary processes. The research described herein used phylogeographic, phylogenomic, and population genetic methods to further understanding of how host traits impact the evolutionary ecology of trematode systems, using avian schistosomes (Digenea: Schistosomatidae) as …