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Full-Text Articles in Medicine and Health Sciences
Case Report: Tocilizumab For The Treatment Of Sars-Cov-2 Infection In A Patient With Aplastic Anemia, Gina Keiffer, Zach French, Lindsay Wilde, Joanne Filicko-O'Hara, Usama Gergis, Adam Binder
Case Report: Tocilizumab For The Treatment Of Sars-Cov-2 Infection In A Patient With Aplastic Anemia, Gina Keiffer, Zach French, Lindsay Wilde, Joanne Filicko-O'Hara, Usama Gergis, Adam Binder
Department of Medicine Faculty Papers
While cytokine storm develops in a minority of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, novel treatment approaches are desperately needed for those in whom it does. Tocilizumab, an interleukin-6 receptor antibody, has been utilized for the treatment of cytokine storm in a number of severe inflammatory conditions, including in patients with severe coronavirus disease 2019 (COVID-19). Here, we present the first published case utilizing this therapy in a patient with underlying immunodeficiency. Our patient with aplastic anemia developed cytokine storm due to COVID-19 manifested by fever, severe hypoxia, pulmonary infiltrates, and elevated inflammatory markers. Following treatment …
Efficacy And Safety Of Bempedoic Acid For Prevention Of Cardiovascular Events And Diabetes: A Systematic Review And Meta-Analysis., Xing Wang, Yu Zhang, Huiwen Tan, Peng Wang, Xi Zha, Weelic Chong, Liangxue Zhou, Fang Fang
Efficacy And Safety Of Bempedoic Acid For Prevention Of Cardiovascular Events And Diabetes: A Systematic Review And Meta-Analysis., Xing Wang, Yu Zhang, Huiwen Tan, Peng Wang, Xi Zha, Weelic Chong, Liangxue Zhou, Fang Fang
Department of Medicine Faculty Papers
BACKGROUND: Bempedoic acid is an oral, once-daily, first-in-class drug being developed for the treatment of hyperlipidemia. However, evidence of bempedoic acid use for the prevention of cardiovascular events and diabetes is lacking. Thus, we aim to evaluate the benefit and safety of bempedoic acid use for the prevention of cardiovascular events and diabetes.
METHODS: We searched Medline, Embase, and the Cochrane Central Register of Controlled Trials with no language restriction from inception until March 3, 2020. Pairs of reviewers independently identified randomized controlled trials comparing the use of bempedoic acid with placebo or no treatment for primary prevention of cardiovascular …
Diabetes Prevention: Your Role As A Healthcare Professional (July 15, 2020), Alexis Skoufalos, Edd, Mitch Kaminski, Md, Mba, Neha Sachdev, Md, Susanne Trexler, Ches, Gina Trignani, Ms, Rd, Ldn, Neva White, Dnp, Crnp-Bc, Cde
Diabetes Prevention: Your Role As A Healthcare Professional (July 15, 2020), Alexis Skoufalos, Edd, Mitch Kaminski, Md, Mba, Neha Sachdev, Md, Susanne Trexler, Ches, Gina Trignani, Ms, Rd, Ldn, Neva White, Dnp, Crnp-Bc, Cde
The Philadelphia Diabetes Prevention Collaborative invites you to learn about the latest in screening, testing and how to easily refer your patients to a National Diabetes Prevention (DPP) lifestyle change program within the greater Philadelphia five-county area.
Featuring Health Promotion Council of Southeastern Pennsylvania, the American Medical Association, and the Center for Urban Health and College of Population Health at Jefferson