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Articles 1 - 30 of 148
Full-Text Articles in Medicine and Health Sciences
Final Scholarly Project: Enhanced Recovery After Surgery (Eras) Guidelines For Pancreaticoduodenectomies, Rebecca Wheeler
Final Scholarly Project: Enhanced Recovery After Surgery (Eras) Guidelines For Pancreaticoduodenectomies, Rebecca Wheeler
Doctor of Nursing Practice Scholarly Projects
A pancreaticoduodenectomy, or Whipple procedure, is the only curative option for pancreatic cancer. For those eligible for tumor resection, the Whipple procedure is a difficult surgery for both the patient and provider. Complications following pancreaticoduodenectomy are numerous and include infection, delayed gastric emptying, high hospital costs, and pancreatic fistulas. Enhanced Recovery After Surgery (ERAS) protocols exist to provide evidence supporting standardization of practices that lead to the improvement of these patient outcomes. An ERAS protocol for the pancreaticoduodenectomy, first established in 2012, is inconsistently implemented in healthcare facilities. Researchers collected data involving the use of the Whipple procedure ERAS guidelines …
Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker
Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker
Doctor of Nursing Practice Scholarly Projects
The final scholarly project proposal is to implement oral care education for nurses in an intensive care unit (ICU). The proposal aims to create a guideline for an investigator to implement oral care recommendations for mechanically ventilated patients in order to reduce ventilator-associated pneumonia (VAP). The proposal consists of obtaining VAP data and oral care charting data for the unit studied, steps for providing oral care education, and analysis recommendations. Oral care involves swabbing the patient’s mouth every two hours with a swab and mouthwash. Oral care education would include handouts and direct teaching. The proposal aims to increase oral …
Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker
Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker
Doctor of Nursing Practice Scholarly Projects
The final scholarly project proposal is to implement oral care education for nurses in an intensive care unit (ICU). The proposal aims to create a guideline for an investigator to implement oral care recommendations for mechanically ventilated patients in order to reduce ventilator-associated pneumonia (VAP). The proposal consists of obtaining VAP data and oral care charting data for the unit studied, steps for providing oral care education, and analysis recommendations. Oral care involves swabbing the patient’s mouth every two hours with a swab and mouthwash. Oral care education would include handouts and direct teaching. The proposal aims to increase oral …
Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker
Educating Nurses On Frequent Oral Care For Mechanically Ventilated Patients: An Evidence-Based Practice Project Proposal, Grace Alford, Susan Butz, Ruth Chavez, Joy Shoemaker
Doctor of Nursing Practice Scholarly Projects
The final scholarly project proposal is to implement oral care education for nurses in an intensive care unit (ICU). The proposal aims to create a guideline for an investigator to implement oral care recommendations for mechanically ventilated patients in order to reduce ventilator-associated pneumonia (VAP). The proposal consists of obtaining VAP data and oral care charting data for the unit studied, steps for providing oral care education, and analysis recommendations. Oral care involves swabbing the patient’s mouth every two hours with a swab and mouthwash. Oral care education would include handouts and direct teaching. The proposal aims to increase oral …
Development And Implementation Of An Evidence Based Practice Guideline Related To The Management Of Adult Angioedema, Megan Przybysz
Development And Implementation Of An Evidence Based Practice Guideline Related To The Management Of Adult Angioedema, Megan Przybysz
Doctor of Nursing Practice Scholarly Projects
Angioedema (AE) is a potentially life-threatening medical condition that occurs with a higher frequency than medical providers may expect, with the emergency department (ED) serving as the usual first point of medical contact for patients. Any hesitation in recognizing AE or inconsideration of the disease process in differential diagnoses may lead to a dangerous delay of care. Due to the potential rapid progression of airway obstruction in AE, inexperienced providers should not attempt intubation, instead deferring to providers experienced in alternative airway techniques (i.e., anesthesia providers). The primary goal of this project is to develop an evidencebased practice guideline for …
Prevention Of Obesity-Related Morbidity & Mortality In Adults, Rachelle Virgin
Prevention Of Obesity-Related Morbidity & Mortality In Adults, Rachelle Virgin
Masters Theses/Capstone Projects
Poster presentation on the prevention of obesity related morbidity and mortality in adults.
Hepatitis Screening, Kathryn Bland
Hepatitis Screening, Kathryn Bland
Masters Theses/Capstone Projects
Project on hepatitis screening.
Small Intestinal Bacterial Overgrowth Testing Strategies, Carla Bonczak
Small Intestinal Bacterial Overgrowth Testing Strategies, Carla Bonczak
Doctor of Nursing Practice Scholarly Projects
Small Intestinal Bacterial Overgrowth (SIBO) is an overgrowth of bacteria in the small intestine. Symptoms such as bloating, abdominal pain and discomfort, malabsorption, nausea, constipation, or diarrhea overlap with several common GI complaints. SIBO affects millions of people worldwide. Many providers are not aware of SIBO or the guidelines that standardize testing and diagnosing.
The Final Scholarly Project (FSP) was based on a literature review that discovered evidence-based literature on SIBO testing strategies such as gut aspirate and culture, clinical symptom presentation, breath testing, nutrient challenge test, and scintigraphy with either lactulose or hydrogen breath testing. To implement the project, …
Nutritional Management: Head And Neck Cancer, Christina Eagle
Nutritional Management: Head And Neck Cancer, Christina Eagle
Masters Theses/Capstone Projects
Nutritional management in head and neck cancer patients will help to promote treatment compliance and reduction of treatment-related co-morbidities.
Mir125a As Molecular Target Of Vitamin D Mediated Inhibition Of Cd4+ T Cell Differentiation Into Th17 Cells In Mrl/Lpr Lupus-Prone Mice, Miranda Hilt
Undergraduate Distinction Papers
The dynamic function of vitamin D in an array of immunomodulatory and anti-inflammatory mechanisms and its implication in the pathogenesis of autoimmune diseases has been the topic of much recent scholarship. Here I attempt to elucidate the molecular mechanism of vitamin D-mediated inhibition of the differentiation of CD4+ T cells into pro-inflammatory Th17 cells in MRL/lpr lupus prone mice by investigating how miR-125a expression is affected by dietary modulation of cholecalciferol (vitamin D3). MRL/MpJ and MRL/lpr mice were split into three experimental groups and fed specially formulated diets that varied in their concentrations of vitamin D. …
Ohiohealth Population Health Diabetes Prevention Program, Erica Kick
Ohiohealth Population Health Diabetes Prevention Program, Erica Kick
Masters Theses/Capstone Projects
OhioHealth Population Health works to provide programs for the community in which they are of no cost. This allows for individuals to be provided with the education they need to live a more sustainable life. The following Program "ENGAGE" looks at diabetes education and management in ways that helps the participants better understand their disease and how to handle things going forward.
Heart Failure, Molly Davis
Heart Failure, Molly Davis
Nursing Student Class Projects (Formerly MSN)
Heart Failure is defined as the pathophysiologic condition in which the heart is unable to generate an adequate cardiac output such that perfusion of tissues or increased diastolic filling pressure of the left ventricle, or both occurs (Huether & McCance, 2019).
Myasthenia Gravis, Rebecca Wheeler
Myasthenia Gravis, Rebecca Wheeler
Nursing Student Class Projects (Formerly MSN)
Myasthenia gravis (MG), a neuromuscular and autoimmune disorder, is not completely understood by clinicians and scientists. The primary cause is thought to be anti-Acetylcholine receptor antibodies that attack the neuromuscular junction, causing destruction of post-synaptic junctional folds and blockade of the receptor. This causes frequent weakness and fatigability of voluntary muscles, making activities of daily living difficult for those living with MG. Although it is not an incredibly prevalent disease, the incidence is increasing in the United States due to better testing and diagnosis. Treatments are available, including cholinesterase inhibitors that raise the concentration of Acetylcholine at the neuromuscular junction …
Perioperative Risks Of The Patient With Heart Failure, Gabrielle Metoyer
Perioperative Risks Of The Patient With Heart Failure, Gabrielle Metoyer
Nursing Student Class Projects (Formerly MSN)
Perioperative Risks of the Patient with Heart Failure
Gabrielle Metoyer
Department of Nursing, Otterbein University
NURS 6810 – Advanced Pathophysiology
Dr. Deanna Batross and Dr. Shivani Bhatnagar
August 5, 2022
Abstract
According to the CDC (2020), heart failure occurs when the heart cannot pump enough blood and oxygen to support other organs in your body. Heart failure is an epidemic disease affecting 1-2% of the population worldwide (Schwinger, 2020). It is one of the leading causes of morbidity and mortality worldwide with an estimated 6.5 million adults with heart failure in the United States (Lo et al., 2021). Medical advances …
Pathophysiology Of Aortic Stenosis, Melissa Lee
Pathophysiology Of Aortic Stenosis, Melissa Lee
Nursing Student Class Projects (Formerly MSN)
Pathophysiology of Aortic Stenosis
Melissa J. Lee
Department of Nursing, Otterbein University
NURS 6810: Advanced Pathophysiology for the Advanced Practice Nurse
Dr. Deana Batross & Dr. Shivani Bhatnagar
July 29, 2022
Pathophysiology of Aortic Stenosis
Proper evaluation of co-morbidities is imperative for patient safety and successful outcomes for patients undergoing anesthesia. Aortic stenosis (AS) is one of the most complex diseases encountered in anesthesia, affecting five percent of older adults and ten percent of the 80-89-year-old-cohort (Joseph et al., 2017). The pathophysiological development of AS is the end result of an inflammatory process caused by endothelial damage from mechanical stress, …
Congestive Heart Failure, Ostap Dvorakevych
Congestive Heart Failure, Ostap Dvorakevych
Nursing Student Class Projects (Formerly MSN)
Abstract
Ostap Dvorakevych
Department of Nursing, Otterbein University
NURS 6810 – Advanced Pathophysiology
Dr. Batross & Dr. Bhatnagar
July 29, 2022
Abstract
To provide the highest quality care, multidisciplinary clinical teams in critical care settings must understand the pathophysiology of the patient conditions they encounter. Congestive heart failure (CHF) is an example of such a condition. CHF is “an abnormality of the myocardial function responsible for failure of the heart to pump blood at a rate commensurate with the requirements of the metabolizing tissue...a condition in which the heart fails to maintain an output sufficient for the needs of the …
Safety Measures In The Epilepsy Monitoring Unit: An Organizational Assessment, Tina Yates
Safety Measures In The Epilepsy Monitoring Unit: An Organizational Assessment, Tina Yates
Doctor of Nursing Practice Scholarly Projects
Long-term video-electroencephalography (EEG) monitoring in the epilepsy monitoring unit (EMU) is an elective procedure and generally safe. Clinical experts determined the EMU protocols at a level-4 comprehensive epilepsy center were not followed correctly. The project is a retrospective chart audit incorporating Ray’s Bureaucratic Caring theoretical framework with Donabedian’s conceptual model. The project objective is to evaluate if safety measures protocols are implemented appropriately in the EMU and determine whether a need exists for quality improvements.
The project reviewed patients admitted to the EMU from September 2021 through November 2021 who developed a generalized tonic clonic (GTCs) seizure with electrographic epileptiform …
Osteoporosis Implications For The Aging Adult, Grace Alford
Osteoporosis Implications For The Aging Adult, Grace Alford
Nursing Student Class Projects (Formerly MSN)
This poster describes the pathophysiology, symptoms, implications for care, and treatment of osteoporosis for advanced practice RNs. The research was conducted within health-related databases. The literature review narrowed the search to only include the pathophysiology, interventions, and care for osteoporosis. Literature was restricted to within the past five years. The research showed that osteoporosis reduces mineral density in bones and can be adequately treated within a short amount of time. It is important for nurses and advanced practice providers to be aware of current guidelines, screenings, and treatments for osteoporosis.
Asthma Pathophysiology, Tyler Wolpert
Asthma Pathophysiology, Tyler Wolpert
Nursing Student Class Projects (Formerly MSN)
This poster will examine the pathophysiology of Asthma, explore signs and symptoms of the disease, and review different treatment modalities. The Doctorate of Nursing (DNP) prepared nurse should be able to identify signs and symptoms of the disease and be prepared to manage the disease from a medical standpoint, as well as with behavior modification. The economic burden of asthma on healthcare yearly is over $82 billion. It is pertinent that continued research is done in the field of asthma to reduce the economic impacts of the disease, as well as to help improve patient outcomes on people living with …
Poster: Sars-Cov-2 Neuroinvasion, Heather M. Tatusko
Poster: Sars-Cov-2 Neuroinvasion, Heather M. Tatusko
Nursing Student Class Projects (Formerly MSN)
Over the last century, science and literature has reported neurological manifestations during various disease outbreaks as well as long-term sequelae following epidemics and pandemics. Some of the first neurological symptoms reported with Coronavirus Disease 2019 (COVID-19; caused by severe acute respiratory syndrome coronavirus 2 [SARS-Cov-2]) were anosmia and dysgeusia, suggesting SARS-CoV-2 penetrance of the central nervous system (CNS). To date, the definite clinical and pathological basis of CNS involvement of SARS-CoV-2 remains poorly understood, with the neurovirulence of SARS-CoV-2 and its neuroinvasive potential remaining largely unknown. The author’s poster will explore neurological manifestations of COVID-19 disease, the direct and indirect …
Effects Of Strong Oxidants Present In Acer Spp. On Hemolysis Methemoglobin Production In Equine Erythrocytes, Gabrielle Mcgeorge, Jeffrey Lehman
Effects Of Strong Oxidants Present In Acer Spp. On Hemolysis Methemoglobin Production In Equine Erythrocytes, Gabrielle Mcgeorge, Jeffrey Lehman
Undergraduate Honors Thesis Projects
Maple toxicosis is a deadly condition affecting equines after they have ingested wilted leaves of the genus Acer (i.e., maple species). It is characterized by hemolytic anemia and methemoglobinemia. Although the toxins responsible for causing toxicosis have not been identified, they are thought to be strong oxidants. The objective of this study is to determine the effect of eight compounds (galloyl derivatives) found in Acer spp. on hemolysis and methemoglobin production in bioassays with equine erythrocytes. Seven of the compounds are known constituents of Acer spp. that are commercially available. One of the compounds--acertannin--was isolated and characterized from leaf extracts …
Sepsis Pathophysiology, Samantha Kingsley
Sepsis Pathophysiology, Samantha Kingsley
Nursing Student Class Projects (Formerly MSN)
Sepsis is one of the most common diagnoses in medical intensive care units (MICUs) worldwide. Sepsis is a medical emergency where prompt intervention is vital to promoting positive patient outcomes. Septic shock develops when sepsis has progressed to the point of persistent hypotension despite appropriate fluid resuscitation. It is important to recognize the early signs of sepsis and intervene to prevent further progression. As the understanding of the pathophysiology has developed further over the years, the treatments and outcomes associated with sepsis have also improved. However, prompt recognition and intervention have always been at the forefront of management and should …
Acute Kidney Injury, Mary Boadu
Acute Kidney Injury, Mary Boadu
Nursing Student Class Projects (Formerly MSN)
This poster presents up to date information regarding acute kidney injury (AKI) which often presents in patients in the intensive care unit (ICU). Most patients may not have identifiable symptoms therefore, advanced practice clinicians are charged with a great responsibility to diagnose, treat and follow-up with such patients. It is pertinent that clinicians recognize AKI early in an effort to prevent adverse consequences as seen in the progression of AKI to chronic kidney disease (CKD).
Chronic Thromboembolic Pulmonary Hypertension, Alyssa Curry
Chronic Thromboembolic Pulmonary Hypertension, Alyssa Curry
Nursing Student Class Projects (Formerly MSN)
Chronic pulmonary hypertension (CTEPH) is a rare and underdiagnosed complication of unresolved acute pulmonary embolism (PE). A chronic fibrotic thrombus replaces the unresolved emboli in the pulmonary vascular bed causing pre-capillary pulmonary hypertension (Mahmud et al., 2018). Symptoms rang from mild nonspecific such as exercise intolerance and dyspnea. As the disease progresses, symptoms present similarly to right ventricular heart failure (Gopalan et al., 2016). Although the pathophysiology and etiology of CTEPH is still not fully understood, risk factors include increased size of the PE, right ventricular strain, chronic inflammation, and defects in fibrinolysis among others (Fernandes et al., 2016). Treatment …
Schizophrenia And Genomics, Tiffini Lasch
Schizophrenia And Genomics, Tiffini Lasch
Nursing Student Class Projects (Formerly MSN)
There are several advancements in genomics under specific categories, such as cancer and autism. Mental health is one of the leading diseases to cause a significant debt burden in today's society. However, genomics has not translated well into mental health treatment. One area of focus is schizophrenia. Those with schizophrenia suffer from severe and devastating symptoms. The symptoms can lead to harsh complications. Which can make it impossible to function in everyday life. Many believe it is not just genetics alone, but also environmental factors that contribute to schizophrenia. Through large genome-wide associated studies, discoveries are being made. There have …
Multiple Sclerosis Pathophysiology, Carolyn Ricketts
Multiple Sclerosis Pathophysiology, Carolyn Ricketts
Nursing Student Class Projects (Formerly MSN)
Abstract
Multiple Sclerosis (MS) is a chronic autoimmune disease characterized by inflammation in the central nervous system and demyelination of the white matter in the brain and spinal cord, leading to lesions and axonal damage, possibly followed by relapse. It is a progressively debilitating disease with a variety of symptoms that mimic other diseases, such as blurred vision, nerve pain, fatigue, weakness, paresthesia, and unsteady gait. It occurs more frequently further from the equator. The pathophysiology of MS is unknown. Several new research theories are emerging which include innate and adaptive immunity playing a role (TH1 and TH17 specifically), infection …
Pathophysiology Of Infective Endocarditis (Ie) Associated With Intravenous Drug Use, Kaleigh Cline
Pathophysiology Of Infective Endocarditis (Ie) Associated With Intravenous Drug Use, Kaleigh Cline
Nursing Student Class Projects (Formerly MSN)
Intravenous drug use (IVDU) is an activity that has the potential of devastating outcomes and affects individuals all over the world. One potential outcome a patient using IV drugs may experience is infective endocarditis (IE). This poster details the significance of IE, its underlying pathophysiology, significance of pathophysiology, signs and symptoms, and nursing implications.
Multiple Myeloma, Anne Doup
Multiple Myeloma, Anne Doup
Nursing Student Class Projects (Formerly MSN)
No abstract provided.
Sepsis, Sarah Jones
Sepsis, Sarah Jones
Nursing Student Class Projects (Formerly MSN)
Sepsis is a dysregulation of the inflammatory response, termed systemic inflammatory response syndrome or SIRS, caused by stimulation of an infectious process. Sepsis often leads to organ dysfunction and increased morbidity, mortality and financial burdens. The goal of treatment is to initiate appropriate antimicrobial therapies, target the underlying infection, optimize intravascular volume, provide fluid resuscitation and maintain adequate perfusion and stroke volume (Taeb, Hooper & Marik, 2017).
Timing of treatment and early detection of sepsis is critical to patients with early warning signs. Sharing this information and potentially making a difference in the outcomes of patients presenting with early signs …
Scleroderma, Erika Lawson
Scleroderma, Erika Lawson
Nursing Student Class Projects (Formerly MSN)
Scleroderma, also known as sclerosis, is an autoimmune disease causing fibrosis in connective tissues. Symptoms include: skin tightening, stiffness and swelling of fingers, weight loss, fatigue, and musculoskeletal pain. Limited scleroderma, also known as CREST syndrome, includes calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia. This presentation is to help increase knowledge of scleroderma pathophysiology and nursing implications that will help medical staff better care for those affected.