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Full-Text Articles in Medicine and Health Sciences

Physicians' Experiences With Brca1/2 Testing In Community Settings., Nancy L. Keating, Kathryn A. Stoeckert, Meredith M. Regan, Lisa Digianni, Judy E. Garber Dec 2008

Physicians' Experiences With Brca1/2 Testing In Community Settings., Nancy L. Keating, Kathryn A. Stoeckert, Meredith M. Regan, Lisa Digianni, Judy E. Garber

Kathryn Sabella

PURPOSE: We surveyed a national sample of nonacademic physicians who ordered BRCA1/2 testing to understand their implementation of genetic testing and to assess recommendations for surveillance and cancer risk management of women with positive test results.

PATIENTS AND METHODS: We surveyed physicians (N = 611 of 1,050; response rate, 58.2%) practicing in nonacademic settings who ordered BRCA1/2 testing during 2004 to 2005. We described physicians' experiences with testing and used multivariable regression models to identify factors associated with more complete counseling and with recommendations for cancer risk management for a BRCA1 mutation carrier.

RESULTS: Most physicians (68.2%) usually or always …


Influenza Genetic Sequence Patents: Where Intellectual Property Clashes With Public Health Needs, Lori B. Andrews, Laura A. Shackelton Apr 2008

Influenza Genetic Sequence Patents: Where Intellectual Property Clashes With Public Health Needs, Lori B. Andrews, Laura A. Shackelton

Lori B. Andrews

A number of advances have recently taken place in influenza virus genomics research, due largely to an extensive genome sequencing project and widespread access to these sequences. If a pandemic virus emerges, whether it is a reassorted A/H5N1 strain or another zoonosis, it is essential that access to information about its genetic sequence is not restricted through intellectual property claims. Products of nature are not patentable inventions, according to US code and the US Supreme Court, and naturally occurring genetic sequences should not be eligible for patenting. Viral genetic sequences represent natural information upon which diagnostics and preventions are necessarily …


Myocardial Infarction And Heart Failure Hospitalization Rates In Maine, Usa – Variability Along The Urban-Rural Continuum, David E. Harris, A. M. Aboueissa, David Hartley Mar 2008

Myocardial Infarction And Heart Failure Hospitalization Rates In Maine, Usa – Variability Along The Urban-Rural Continuum, David E. Harris, A. M. Aboueissa, David Hartley

David Hartley

Cardiovascular disease, including myocardial infarction (MI) and heart failure (HF), remains the leading cause of death in wealthy countries and is of increasing concern in low- and middle-income countries as risk factors such as smoking and obesity become more common around the globe. Within each country the health burden of MI and HF generally falls more heavily on those who live in rural areas and on those who live in communities with lower average socioeconomic status (SES). Hospitalization rates are an important measure of community health because high rates may indicate a high burden of poor health, while inappropriately low …


Myocardial Infarction And Heart Failure Hospitalization Rates In Maine, Usa – Variability Along The Urban-Rural Continuum, David E. Harris, A. M. Aboueissa, David Hartley Mar 2008

Myocardial Infarction And Heart Failure Hospitalization Rates In Maine, Usa – Variability Along The Urban-Rural Continuum, David E. Harris, A. M. Aboueissa, David Hartley

David Hartley

Cardiovascular disease, including myocardial infarction (MI) and heart failure (HF), remains the leading cause of death in wealthy countries and is of increasing concern in low- and middle-income countries as risk factors such as smoking and obesity become more common around the globe. Within each country the health burden of MI and HF generally falls more heavily on those who live in rural areas and on those who live in communities with lower average socioeconomic status (SES). Hospitalization rates are an important measure of community health because high rates may indicate a high burden of poor health, while inappropriately low …


Sampling-Based Approach To Determining Outcomes Of Patients Lost To Follow-Up In Antiretroviral Therapy Scale-Up Programs In Africa, Elvin H. Geng Dec 2007

Sampling-Based Approach To Determining Outcomes Of Patients Lost To Follow-Up In Antiretroviral Therapy Scale-Up Programs In Africa, Elvin H. Geng

Elvin H Geng

No abstract provided.


Childhood Sexual Abuse In Black Men Who Have Sex With Men: Results From Three Qualitative Studies, Sheldon D. Fields, David J. Malebranche, Sonja Feist-Price Dec 2007

Childhood Sexual Abuse In Black Men Who Have Sex With Men: Results From Three Qualitative Studies, Sheldon D. Fields, David J. Malebranche, Sonja Feist-Price

David J Malebranche

This report describes the high prevalence and context of childhood sexual abuse (CSA) among Black men who have sex with men (MSM) across 3 independent qualitative studies. Semistructured one-on-one interviews were conducted with 87 Black MSM across 3 cities (Rochester, NY, n=28; Lexington, KY/Atlanta, GA, n=30; and Atlanta, GA, n =29). A combined CSA prevalence of 32% (28/87) was found among the 3 samples, despite variation in geographic location, mean age, and sexual identification. Common themes emerging across the 3 samples included prolonged and repeated abuse by a close male relative; blaming of same-sex desire on CSA; and descriptions of …


Bisexually Active Black Men In The United States And Hiv: Acknowledging More Than The "Down Low", David J. Malebranche Dec 2007

Bisexually Active Black Men In The United States And Hiv: Acknowledging More Than The "Down Low", David J. Malebranche

David J Malebranche

HIV is disproportionately impacting Black men who have sex with men and heterosexual women in theUnited States. Current speculation posits a ‘‘bisexual bridge’’ of HIV transmission connecting these two subpopulations of the Black community. Specifically, bisexually active Black men who identify as heterosexual but do not disclose their same-sex behavior, or ‘‘down low’’ (DL) men, have received the most attention and blame as the primary group fueling this epidemic. This essay explores the current knowledge and limitations of public health research on bisexually active Black men. Implications for future research initiatives are discussed.


Escalating Levels Of Access To In-Hospital Care And Stroke Mortality., Gustavo Saposnik Dec 2007

Escalating Levels Of Access To In-Hospital Care And Stroke Mortality., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.


Stroke Outcome In Those Over 80: A Multicenter Cohort Study Across Canada., Gustavo Saposnik Dec 2007

Stroke Outcome In Those Over 80: A Multicenter Cohort Study Across Canada., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.


Unusual Burials And Necrophobia: An Insight Into The Burial Archaeology Of Fear, Anastasia Tsaliki Dec 2007

Unusual Burials And Necrophobia: An Insight Into The Burial Archaeology Of Fear, Anastasia Tsaliki

Dr Anastasia Tsaliki, PhD

No abstract provided.