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Gut Integrity, Microbial Translocation, Immune Activation, Inflammation And Vitamin D In Drug Users Living With Hiv, Jacqueline S. Hernandez
Gut Integrity, Microbial Translocation, Immune Activation, Inflammation And Vitamin D In Drug Users Living With Hiv, Jacqueline S. Hernandez
FIU Electronic Theses and Dissertations
The purpose of this study was to examine associations between MT, immune activation, inflammation, gut integrity and vitamin D status in the context of cocaine use among People Living with HIV (PLWH). One hundred cocaine and non-cocaine users living with HIV were selected from the Miami Adult Studies in HIV cohort. Blood samples were collected to assess MT (LPS), immune activation (sCD163 and sCD27), inflammation (IL-6, TNF-a, hs-CRP, IL-17 and IL-22), gut integrity damage (I-FABP) and vitamin D status. Data on socio-demographic characteristics, anthropometrics, diet and disease progression were collected. Descriptive statistics, independent t-test, multiple linear and logistic regressions were …