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Full-Text Articles in Medicine and Health Sciences
The Gut Microbiome Modulates Associations Between Adherence To A Mediterranean-Style Diet, Abdominal Adiposity, And C-Reactive Protein In Population-Level Analysis, Amy Jennings, Tilman Kühn, Nicola P. Bondonno, Sabina Waniek, Corinna Bang, Andre Franke, Jan Kassubek, Hans-Peter Müller, Marcus Both, Katharina S. Weber, Wolfgang Lieb, Aedín Cassidy
The Gut Microbiome Modulates Associations Between Adherence To A Mediterranean-Style Diet, Abdominal Adiposity, And C-Reactive Protein In Population-Level Analysis, Amy Jennings, Tilman Kühn, Nicola P. Bondonno, Sabina Waniek, Corinna Bang, Andre Franke, Jan Kassubek, Hans-Peter Müller, Marcus Both, Katharina S. Weber, Wolfgang Lieb, Aedín Cassidy
Research outputs 2022 to 2026
Background: Adherence to a Mediterranean-style dietary pattern is likely to have variable effects on body composition, but the impact of gut microbiome on this relationship is unknown. Objectives: To examine the potential mediating effect of the gut microbiome on the associations between Alternate Mediterranean Diet (aMed) scores, abdominal adiposity, and inflammation in population-level analysis. Design: In a community-based sample aged 25 to 83 y (n = 620; 41% female) from Northern Germany, we assessed the role of the gut microbiome, sequenced from 16S rRNA genes, on the associations between aMed scores, estimated using validated food-frequency questionnaires, magnetic resonance imaging-determined visceral …
Altered Dietary Behaviour During Pregnancy Impacts Systemic Metabolic Phenotypes, Charlotte E. Rowley, Samantha Lodge, Siobhon Egan, Catherine Itsiopoulos, Claus T. Christophersen, Desiree Silva, Elizabeth Kicic-Starcevich, Therese A. O’Sullivan, Julien Wist, Jeremy Nicholson, Gary Frost, Elaine Holmes, Nina D’Vaz
Altered Dietary Behaviour During Pregnancy Impacts Systemic Metabolic Phenotypes, Charlotte E. Rowley, Samantha Lodge, Siobhon Egan, Catherine Itsiopoulos, Claus T. Christophersen, Desiree Silva, Elizabeth Kicic-Starcevich, Therese A. O’Sullivan, Julien Wist, Jeremy Nicholson, Gary Frost, Elaine Holmes, Nina D’Vaz
Research outputs 2022 to 2026
Rationale: Evidence suggests consumption of a Mediterranean diet (MD) can positively impact both maternal and offspring health, potentially mediated by a beneficial effect on inflammatory pathways. We aimed to apply metabolic profiling of serum and urine samples to assess differences between women who were stratified into high and low alignment to a MD throughout pregnancy and investigate the relationship of the diet to inflammatory markers. Methods: From the ORIGINS cohort, 51 pregnant women were stratified for persistent high and low alignment to a MD, based on validated MD questionnaires. 1H Nuclear Magnetic Resonance (NMR) spectroscopy was used to investigate the …
A Randomised Controlled Crossover Trial Investigating The Short-Term Effects Of Different Types Of Vegetables On Vascular And Metabolic Function In Middle-Aged And Older Adults With Mildly Elevated Blood Pressure: The Vegetables For Vascular Health (Vessel) Study Protocol, Emma Connolly, Catherine P. Bondonno, Marc Sim, Simone Radavelli-Bagatini, Kevin D. Croft, Mary C. Boyce, Anthony P. James, Karin Clark, Reindolf Anokye, Nicola P. Bondonno, Richard Woodman, Amanda Devine, Seng Khee Gan, Carl J. Schultz, Richard F. Mithen, Joshua Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst
A Randomised Controlled Crossover Trial Investigating The Short-Term Effects Of Different Types Of Vegetables On Vascular And Metabolic Function In Middle-Aged And Older Adults With Mildly Elevated Blood Pressure: The Vegetables For Vascular Health (Vessel) Study Protocol, Emma Connolly, Catherine P. Bondonno, Marc Sim, Simone Radavelli-Bagatini, Kevin D. Croft, Mary C. Boyce, Anthony P. James, Karin Clark, Reindolf Anokye, Nicola P. Bondonno, Richard Woodman, Amanda Devine, Seng Khee Gan, Carl J. Schultz, Richard F. Mithen, Joshua Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst
Research outputs 2014 to 2021
A diet rich in fruits and vegetables is recommended for cardiovascular health. However, the majority of Australians do not consume the recommended number of vegetable servings each day. Furthermore, intakes of vegetables considered to have the greatest cardiovascular benefit are often very low. Results from prospective observational studies indicate that a higher consumption of cruciferous vegetables (e.g. broccoli, cabbage, cauliflower) is associated with lower cardiovascular disease risk. This may be due to the presence of specific nutrients and bioactive compounds found almost exclusively, or at relatively high levels, in cruciferous vegetables. Therefore, the aim of this randomised controlled crossover trial …