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Full-Text Articles in Medicine and Health Sciences
Association Of Dietary Nitrate Intake With The 15-Year Incidence Of Age-Related Macular Degeneration, Bamini Gopinath, Gerald Liew, Annette Kifley, Joshua R. Lewis, Catherine Bondonno, Nichole Joachim, Jonathan M. Hodgson, Paul Mitchell
Association Of Dietary Nitrate Intake With The 15-Year Incidence Of Age-Related Macular Degeneration, Bamini Gopinath, Gerald Liew, Annette Kifley, Joshua R. Lewis, Catherine Bondonno, Nichole Joachim, Jonathan M. Hodgson, Paul Mitchell
Research outputs 2014 to 2021
Background
Dietary nitrate, found predominantly in green leafy vegetables and beetroot, is a precursor of nitric oxide. Under- or overproduction of nitric oxide is implicated in the etiology of several eye diseases. However, the potential influence of dietary nitrate intake on age-related macular degeneration (AMD) risk has not been assessed.
Objective
To investigate the temporal association between dietary nitrate intake (from both vegetable and nonvegetable sources) and the 15-year incidence of AMD, independent of potential confounders.
Design
A longitudinal cohort study conducted from 1992-1994 to 2007-2009.
Participants/setting
The Blue Mountains Eye Study is a population-based study of adults aged 49+ …